Moritz A (2003) CST Curation Set: 86; Year: 2003; Biosample/Treatment: cell line, K562/pervanadate; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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Y223-p - Btk (human) ▲

Modsite: LKKVVALyDyMPMNA SwissProt Entrez-Gene Orthologous residues Btk (human): Y223‑p, Btk iso2 (human): Y257‑p, Btk (mouse): Y223‑p, Btk (rat): Y224‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y225-p - Btk (human) ▲

Modsite: KVVALyDyMPMNAND SwissProt Entrez-Gene Orthologous residues Btk (human): Y225‑p, Btk iso2 (human): Y259‑p, Btk (mouse): Y225‑p, Btk (rat): Y226‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y296-p - DOK1 (human) ▲

Modsite: LDsPPALyAEPLDSL SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y296‑p, DOK1 iso3 (human): Y157‑p, DOK1 (mouse): Y295‑p, DOK1 (rat): Y295‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y362-p - DOK1 (human) ▲

Modsite: DPKEDPIyDEPEGLA SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y362‑p, DOK1 iso3 (human): Y223‑p, DOK1 (mouse): Y361‑p, DOK1 (rat): Y361‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y377-p - DOK1 (human) ▲

Modsite: PVPPQGLyDLPREPK SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y377‑p, DOK1 iso3 (human): Y238‑p, DOK1 (mouse): Y376‑p, DOK1 (rat): Y376‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y251-p - EIF2A (human) ▲

Modsite: DKTGAsyyGEQTLHy SwissProt Entrez-Gene Orthologous residues EIF2A (human): Y251‑p, EIF2A iso2 (human): Y37‑p, EIF2A (mouse): Y251‑p, EIF2A (rat): Y211‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y545-p - GIT1 (human) ▲

Modsite: ELEDDAIysVHVPAG SwissProt Entrez-Gene Orthologous residues GIT1 (human): Y545‑p, GIT1 iso3 (human): Y554‑p, GIT1 (mouse): Y554‑p, GIT1 (rat): Y554‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y611-p - HSP70 (human) ▲

Modsite: NPIIsGLyQGAGGPG SwissProt Entrez-Gene Orthologous residues HSP70 (human): Y611‑p, HSP70 iso2 (human): Y556‑p, HSP70 (mouse): Y611‑p, HSP70 (rat): Y611‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y835-p - NICE-4 (human) ▲

Modsite: TrFPLDyysIPFPtP SwissProt Entrez-Gene Orthologous residues NICE‑4 (human): Y835‑p, NICE‑4 iso2 (human): Y835‑p, NICE‑4 iso5 (human): Y835‑p, NICE‑4 (mouse): Y855‑p, NICE‑4 iso2 (mouse): Y866‑p, NICE‑4 iso3 (mouse): Y835‑p, NICE‑4 (rat): Y855‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y835-p - NICE-4 iso2 (human) ▲

Modsite: TRFPLDyySIPFPTP SwissProt Entrez-Gene Orthologous residues NICE‑4 (human): Y835‑p, NICE‑4 iso2 (human): Y835‑p, NICE‑4 iso5 (human): Y835‑p, NICE‑4 (mouse): Y855‑p, NICE‑4 iso2 (mouse): Y866‑p, NICE‑4 iso3 (mouse): Y835‑p, NICE‑4 (rat): Y855‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y1774-p - NuMA-1 (human) ▲

Modsite: VEsLEsLyFtPIPAR SwissProt Entrez-Gene Orthologous residues NuMA‑1 (human): Y1774‑p, NuMA‑1 iso2 (human): Y1760‑p, NuMA‑1 iso4 (human): ‑, NuMA‑1 (mouse): Y1756‑p, NuMA‑1 (rat): Y1740‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y986-p - SHIP-2 (human) ▲

Modsite: NsFNNPAyyVLEGVP SwissProt Entrez-Gene Orthologous residues SHIP‑2 (human): Y986‑p, SHIP‑2 iso2 (human): Y744‑p, SHIP‑2 (mouse): Y987‑p, SHIP‑2 (rat): Y987‑p, SHIP‑2 iso2 (rat): Y987‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y20-p - TfR (human) ▲
Modsite: FGGEPLsytRFsLAR SwissProt Entrez-Gene Orthologous residues TfR (human): Y20‑p, TfR (mouse): Y20‑p, TfR (rat): Y20‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y280-p - TSAd (human) ▲

Modsite: PKPSNPIyNEPDEPI SwissProt Entrez-Gene Orthologous residues TSAd (human): Y280‑p, TSAd iso4 (human): Y262‑p, TSAd (mouse): Y300‑p, TSAd (rat): Y302‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y290-p - TSAd (human) ▲

Modsite: PDEPIAFyAMGrGsP SwissProt Entrez-Gene Orthologous residues TSAd (human): Y290‑p, TSAd iso4 (human): Y272‑p, TSAd (mouse): Y310‑p, TSAd (rat): Y312‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human

Y840-p - UBAP2 (human) ▲

Modsite: SRLPVDyyGIPFAAP SwissProt Entrez-Gene Orthologous residues UBAP2 (human): Y840‑p, UBAP2 (mouse): Y854‑p, UBAP2 (rat): Y849‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, chronic myelogenous leukemia Relevant cell lines - cell types - tissues:  K562 (erythroid) Cellular systems studied:  cell lines Species studied:  human