Curated Information
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Home > Curated Information Page > Cst Curation Set #35
Goss V (2003) CST Curation Set: 35; Year: 2003; Biosample/Treatment: cell line, BaF3/pervanadate &'||' Flt3 ligand; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y76-p - BAD (mouse)
Modsite: TEDQPGPyLAPGLLG SwissProt Entrez-Gene
Orthologous residues
BAD (human): H37‑p, BAD (mouse): Y76‑p, BAD (rat): Y76‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y223-p - Btk (mouse)
Modsite: LKKVVALyDyMPMNA SwissProt Entrez-Gene
Orthologous residues
Btk (human): Y223‑p, Btk iso2 (human): Y257‑p, Btk (mouse): Y223‑p, Btk (rat): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y225-p - Btk (mouse)
Modsite: KVVALyDyMPMNAND SwissProt Entrez-Gene
Orthologous residues
Btk (human): Y225‑p, Btk iso2 (human): Y259‑p, Btk (mouse): Y225‑p, Btk (rat): Y226‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y213-p - CDV-3 (mouse)
Modsite: PQGPPEIysDTQFPs SwissProt Entrez-Gene
Orthologous residues
CDV‑3 (human): Y190‑p, CDV‑3 iso2 (human): Y190‑p, CDV‑3 (mouse): Y213‑p, CDV‑3 (rat): Y213‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y295-p - DOK1 (mouse)
Modsite: LGsPPALyAEPLDSL SwissProt Entrez-Gene
Orthologous residues
DOK1 (human): Y296‑p, DOK1 iso3 (human): Y157‑p, DOK1 (mouse): Y295‑p, DOK1 (rat): Y295‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y855-p - NICE-4 (mouse)
Modsite: TRFPLDyysIPFPtP SwissProt Entrez-Gene
Orthologous residues
NICE‑4 (human): Y835‑p, NICE‑4 iso2 (human): Y835‑p, NICE‑4 iso5 (human): Y835‑p, NICE‑4 (mouse): Y855‑p, NICE‑4 iso2 (mouse): Y866‑p, NICE‑4 iso3 (mouse): Y835‑p, NICE‑4 (rat): Y855‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y632-p - PEAK1 (mouse)
Modsite: IVINPNAyDNLAIyK SwissProt Entrez-Gene
Orthologous residues
PEAK1 (human): Y635‑p, PEAK1 (mouse): Y632‑p, PEAK1 (rat): Y631‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y638-p - PEAK1 (mouse)
Modsite: AyDNLAIyKSFLGts SwissProt Entrez-Gene
Orthologous residues
PEAK1 (human): Y641‑p, PEAK1 (mouse): Y638‑p, PEAK1 (rat): Y637‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y323-p - PSTPIP2 (mouse)
Modsite: RIPDDPDysVVEDyS SwissProt Entrez-Gene
Orthologous residues
PSTPIP2 (human): Y323‑p, PSTPIP2 iso2 (human): , PSTPIP2 (mouse): Y323‑p, PSTPIP2 (rat): Y323‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y333-p - PSTPIP2 (mouse)
Modsite: VEDySLLyQ______ SwissProt Entrez-Gene
Orthologous residues
PSTPIP2 (human): Y333‑p, PSTPIP2 iso2 (human): , PSTPIP2 (mouse): Y333‑p, PSTPIP2 (rat): Y333‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y17-p - SEPT2 (mouse)
Modsite: INPEtPGyVGFANLP SwissProt Entrez-Gene
Orthologous residues
SEPT2 (human): Y17‑p, SEPT2 iso2 (human): Y52‑p, SEPT2 iso3 (human): Y17‑p, SEPT2 (mouse): Y17‑p, SEPT2 (rat): Y17‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y260-p - SKAP2 (mouse)
Modsite: QPIDDEIyEELPEEE SwissProt Entrez-Gene
Orthologous residues
SKAP2 (human): Y261‑p, SKAP2 (mouse): Y260‑p, SKAP2 (rat): Y260‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y342-p - Syk (mouse)
Modsite: LPMDTEVyESPyADP SwissProt Entrez-Gene
Orthologous residues
Syk (human): Y348‑p, Syk iso2 (human): Y325‑p, Syk (mouse): Y342‑p, Syk (rat): Y342‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y346-p - Syk (mouse)
Modsite: TEVyESPyADPEEIR SwissProt Entrez-Gene
Orthologous residues
Syk (human): Y352‑p, Syk iso2 (human): Y329‑p, Syk (mouse): Y346‑p, Syk (rat): Y346‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y931-p - TBC1D8B (mouse)
Modsite: LSTEELLyFSQLQVS SwissProt Entrez-Gene
Orthologous residues
TBC1D8B (human): Y932‑p, TBC1D8B (mouse): Y931‑p, TBC1D8B (rat): Y931‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y854-p - UBAP2 (mouse)
Modsite: SRLPMDyyGIPFAAP SwissProt Entrez-Gene
Orthologous residues
UBAP2 (human): Y840‑p, UBAP2 (mouse): Y854‑p, UBAP2 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse

Y293-p - WASP (mouse)
Modsite: AETsKLIyDFIEDQG SwissProt Entrez-Gene
Orthologous residues
WASP (human): Y291‑p, WASP (mouse): Y293‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  BaF3 ('B lymphocyte, precursor')
Cellular systems studied:  cell lines
Species studied:  mouse