Curated Information
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Home > Curated Information Page > Cst Curation Set #6620
Rikova K (2009) CST Curation Set: 6620; Year: 2009; Biosample/Treatment: tissue, lung/untreated; Disease: lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S1497-p - ABCA12 (human)
Modsite: SIALIGGsRVVILDE SwissProt Entrez-Gene
Orthologous residues
ABCA12 (human): S1497‑p, ABCA12 (mouse): S1497‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y24-p - ANXA2 (human)
Modsite: HstPPsAyGsVkAyt SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y24‑p, ANXA2 iso2 (human): Y42‑p, ANXA2 (mouse): Y24‑p, ANXA2 (rat): Y24‑p, ANXA2 (dog): Y24‑p, ANXA2 (cow): Y24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y449-p - CPT1B (human)
Modsite: ALLHGNCyNRWFDKS SwissProt Entrez-Gene
Orthologous residues
CPT1B (human): Y449‑p, CPT1B iso4 (human): Y368‑p, CPT1B (mouse): Y449‑p, CPT1B (rat): Y449‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y221-p - CRK (human)
Modsite: GGPEPGPyAQPsVNt SwissProt Entrez-Gene
Orthologous residues
CRK (human): Y221‑p, CRK iso2 (human): , CRK (mouse): Y221‑p, CRK iso3 (mouse): , CRK (rat): Y221‑p, CRK (chicken): Y222‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y207-p - CRKL (human)
Modsite: IPEPAHAyAQPQttt SwissProt Entrez-Gene
Orthologous residues
CRKL (human): Y207‑p, CRKL (mouse): Y207‑p, CRKL (rat): Y207‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

T185-p - ERK2 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): T185‑p, ERK2 (mouse): T183‑p, ERK2 (rat): T183‑p, ERK2 (chicken): T193‑p, ERK2 (cow): T185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y576-p - FAK (human)
Modsite: RyMEDstyyKAsKGK SwissProt Entrez-Gene
Orthologous residues
FAK (human): Y576‑p, FAK iso2 (human): Y424‑p, FAK iso5 (human): Y576‑p, FAK (mouse): Y576‑p, FAK iso2 (mouse): Y607‑p, FAK iso4 (mouse): Y576‑p, FAK iso9 (mouse): , FAK (rat): Y576‑p, FAK (chicken): Y576‑p, FAK iso5 (chicken):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y577-p - FAK (human)
Modsite: yMEDstyyKAsKGKL SwissProt Entrez-Gene
Orthologous residues
FAK (human): Y577‑p, FAK iso2 (human): Y425‑p, FAK iso5 (human): Y577‑p, FAK (mouse): Y577‑p, FAK iso2 (mouse): Y608‑p, FAK iso4 (mouse): Y577‑p, FAK iso9 (mouse): , FAK (rat): Y577‑p, FAK (chicken): Y577‑p, FAK iso5 (chicken):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

T1410-p - FAT2 (human)
Modsite: VIARPLDtRRRSNYN SwissProt Entrez-Gene
Orthologous residues
FAT2 (human): T1410‑p, FAT2 (mouse): T1410‑p, FAT2 (rat): T1410‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

S138-p - FETUA (human)
Modsite: kCDssPDsAEDVrkV SwissProt Entrez-Gene
Orthologous residues
FETUA (human): S138‑p, FETUA (mouse): S138‑p, FETUA (rat): S138‑p, FETUA (cow): S138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

S950-p - FREM1 (human)
Modsite: GVTVDQFsQRDVISE SwissProt Entrez-Gene
Orthologous residues
FREM1 (human): S950‑p, FREM1 (mouse): S975‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

T155-p - JMJD2A (human)
Modsite: WNIGRLRtILDLVEK SwissProt Entrez-Gene
Orthologous residues
JMJD2A (human): T155‑p, JMJD2A (mouse): T155‑p, JMJD2A (rat): T155‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

S98-p - JRKL (human)
Modsite: RAkGNPIsGPICAKR SwissProt Entrez-Gene
Orthologous residues
JRKL (human): S98‑p, JRKL (mouse): S98‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

S1943-p - MYH9 (human)
Modsite: RKGAGDGsDEEVDGK SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): S1943‑p, MYH9 iso2 (human): S1365‑p, MYH9 (mouse): S1943‑p, MYH9 (rat): S1944‑p, MYH9 (cow): S1942‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

T366-p - NDRG1 (human)
Modsite: GtRsRsHtsEGAHLD SwissProt Entrez-Gene
Orthologous residues
NDRG1 (human): T366‑p, NDRG1 iso2 (human): T300‑p, NDRG1 iso3 (human): T285‑p, NDRG1 (mouse): T366‑p, NDRG1 (rat): T366‑p, NDRG1 (cow):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y118-p - PXN (human)
Modsite: VGEEEHVysFPNkQk SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y418‑p, Src iso1 (mouse): Y424‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y530-p - Src (human)
Modsite: FTstEPQyQPGENL_ SwissProt Entrez-Gene
Orthologous residues
Src (human): Y530‑p, Src iso2 (human): Y536‑p, Src (mouse): Y529‑p, Src iso1 (mouse): Y535‑p, Src (rat): Y530‑p, Src (chicken): Y527‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y704-p - STAT3 iso2 (human)
Modsite: ADPGAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y694-p - STAT5A (human)
Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): , STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y699-p - STAT5B (human)
Modsite: tAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5B (human): Y699‑p, STAT5B (mouse): Y699‑p, STAT5B (rat): Y699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y366-p - tensin 1 iso1 (human)
Modsite: GPLDGsLyAKVKKKD SwissProt Entrez-Gene
Orthologous residues
tensin 1 (human): Y491‑p, tensin 1 iso1 (human): Y366‑p, tensin 1 iso2 (human): , tensin 1 (mouse): Y537‑p, tensin 1 (rat): Y539‑p, tensin 1 (cow): Y366‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y483-p - tensin 2 (human)
Modsite: GPLDGsPyAQVQRPP SwissProt Entrez-Gene
Orthologous residues
tensin 2 (human): Y483‑p, tensin 2 iso2 (human): Y483‑p, tensin 2 iso4 (human): Y493‑p, tensin 2 (mouse): Y483‑p, tensin 2 (rat): Y483‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

T445-p - TNFRSF8 (human)
Modsite: sRPRRsstQLRsGAs SwissProt Entrez-Gene
Orthologous residues
TNFRSF8 (human): T445‑p, TNFRSF8 (mouse): T346‑p, TNFRSF8 (rat): T341‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for lung cancer sample