Curated Information
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Home > Curated Information Page > Cst Curation Set #6435
Tucker M (2009) CST Curation Set: 6435; Year: 2009; Biosample/Treatment: tissue, skin/untreated; Disease: melanoma skin cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y24-p - ANXA2 (human)
Modsite: HstPPsAyGsVkAyt SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y24‑p, ANXA2 iso2 (human): Y42‑p, ANXA2 (mouse): Y24‑p, ANXA2 (rat): Y24‑p, ANXA2 (dog): Y24‑p, ANXA2 (cow): Y24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y792-p - ARHGAP42 (human)
Modsite: DtAssNGyQRPGsVV SwissProt Entrez-Gene
Orthologous residues
ARHGAP42 (human): Y792‑p, ARHGAP42 (mouse): Y759‑p, ARHGAP42 (rat): Y793‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y447-p - Brk (human)
Modsite: RLSSFtsyENPT___ SwissProt Entrez-Gene
Orthologous residues
Brk (human): Y447‑p, Brk (mouse): Y447‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y899-p - CLTC (human)
Modsite: RFLRENPyyDsrVVG SwissProt Entrez-Gene
Orthologous residues
CLTC (human): Y899‑p, CLTC iso2 (human): Y899‑p, CLTC (mouse): Y899‑p, CLTC iso3 (mouse): , CLTC (rat): Y899‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y900-p - CLTC (human)
Modsite: FLRENPyyDsrVVGk SwissProt Entrez-Gene
Orthologous residues
CLTC (human): Y900‑p, CLTC iso2 (human): Y900‑p, CLTC (mouse): Y900‑p, CLTC iso3 (mouse): , CLTC (rat): Y900‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T292-p - CNKSR2 (human)
Modsite: DPSGVILtLKKRPQS SwissProt Entrez-Gene
Orthologous residues
CNKSR2 (human): T292‑p, CNKSR2 iso2 (human): T292‑p, CNKSR2 iso4 (human): , CNKSR2 iso5 (human): T292‑p, CNKSR2 (mouse): T292‑p, CNKSR2 (rat): T292‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S218-p - DERL1 (human)
Modsite: PSRrGGVsGFGVPPA SwissProt Entrez-Gene
Orthologous residues
DERL1 (human): S218‑p, DERL1 iso2 (human): S198‑p, DERL1 (mouse): S218‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y449-p - DOK1 (human)
Modsite: KsHNsALysQVQKSG SwissProt Entrez-Gene
Orthologous residues
DOK1 (human): Y449‑p, DOK1 iso3 (human): Y310‑p, DOK1 (mouse): Y450‑p, DOK1 (rat): Y448‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T202-p - ERK1 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): T202‑p, ERK1 iso2 (human): T202‑p, ERK1 iso3 (human): T202‑p, ERK1 (mouse): T203‑p, ERK1 (rat): T203‑p, ERK1 (hamster): T192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T185-p - ERK2 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): T185‑p, ERK2 (mouse): T183‑p, ERK2 (rat): T183‑p, ERK2 (chicken): T193‑p, ERK2 (cow): T185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y19-p - Exportin-7 (human)
Modsite: ENLCKQLyETTDTTT SwissProt Entrez-Gene
Orthologous residues
Exportin‑7 (human): Y19‑p, Exportin‑7 (mouse): Y19‑p, Exportin‑7 (rat): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y261-p - Fes (human)
Modsite: RIQPEAEyQGFLRQY SwissProt Entrez-Gene
Orthologous residues
Fes (human): Y261‑p, Fes (mouse): Y261‑p, Fes (rat): Y261‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S138-p - FETUA (human)
Modsite: kCDssPDsAEDVrkV SwissProt Entrez-Gene
Orthologous residues
FETUA (human): S138‑p, FETUA (mouse): S138‑p, FETUA (rat): S138‑p, FETUA (cow): S138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y401-p - G6PD (human)
Modsite: VQPNEAVytkMMTKk SwissProt Entrez-Gene
Orthologous residues
G6PD (human): Y401‑p, G6PD iso2 (human): Y447‑p, G6PD iso3 (human): Y431‑p, G6PD (mouse): Y401‑p, G6PD (rat): Y401‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y507-p - G6PD (human)
Modsite: GFQyEGtykWVNPHk SwissProt Entrez-Gene
Orthologous residues
G6PD (human): Y507‑p, G6PD iso2 (human): Y553‑p, G6PD iso3 (human): Y537‑p, G6PD (mouse): Y507‑p, G6PD (rat): Y507‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y411-p - Hck (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S102-p - HMGA1 (human)
Modsite: EEGIsQEssEEEQ__ SwissProt Entrez-Gene
Orthologous residues
HMGA1 (human): S102‑p, HMGA1 iso2 (human): S91‑p, HMGA1 (mouse): S102‑p, HMGA1 iso2 (mouse): S91‑p, HMGA1 iso3 (mouse): S101‑p, HMGA1 (rat): S102‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S103-p - HMGA1 (human)
Modsite: EGIsQEssEEEQ___ SwissProt Entrez-Gene
Orthologous residues
HMGA1 (human): S103‑p, HMGA1 iso2 (human): S92‑p, HMGA1 (mouse): S103‑p, HMGA1 iso2 (mouse): S92‑p, HMGA1 iso3 (mouse): S102‑p, HMGA1 (rat): S103‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y180-p - hnRNP A0 (human)
Modsite: AVPkEDIysGGGGGG SwissProt Entrez-Gene
Orthologous residues
hnRNP A0 (human): Y180‑p, hnRNP A0 (mouse): H180‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y185-p - JNK2 (human)
Modsite: tNFMMtPyVVtRYYR SwissProt Entrez-Gene
Orthologous residues
JNK2 (human): Y185‑p, JNK2 iso2 (human): Y185‑p, JNK2 iso3 (human): Y185‑p, JNK2 (mouse): Y185‑p, JNK2 (rat): Y185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y46-p - K14 (human)
Modsite: sCRAPstyGGGLSVs SwissProt Entrez-Gene
Orthologous residues
K14 (human): Y46‑p, K14 (mouse): Y42‑p, K14 (rat): Y42‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S435-p - K14 (human)
Modsite: SsQFssGsQssRDVT SwissProt Entrez-Gene
Orthologous residues
K14 (human): S435‑p, K14 (mouse): S447‑p, K14 (rat): S448‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y66-p - K5 (human)
Modsite: GyGsRsLyNLGGskR SwissProt Entrez-Gene
Orthologous residues
K5 (human): Y66‑p, K5 (mouse): Y63‑p, K5 (rat): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y62-p - K6a (human)
Modsite: GFGsrsLyGLGGsKR SwissProt Entrez-Gene
Orthologous residues
K6a (human): Y62‑p, K6a (mouse): Y60‑p, K6a (rat): C60‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y62-p - K6c (human)
Modsite: GFGsrsLyGLGGsKR SwissProt Entrez-Gene
Orthologous residues
K6c (human): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y504-p - kindlin-3 (human)
Modsite: SAEGLNPyGLVAPRF SwissProt Entrez-Gene
Orthologous residues
kindlin‑3 (human): Y504‑p, kindlin‑3 iso2 (human): Y500‑p, kindlin‑3 (mouse): Y502‑p, kindlin‑3 (rat): Y502‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y62-p - KRT6B (human)
Modsite: GFGsrsLyGLGGsKR SwissProt Entrez-Gene
Orthologous residues
KRT6B (human): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y397-p - LYN (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y397‑p, LYN iso2 (human): Y376‑p, LYN (mouse): Y397‑p, LYN iso2 (mouse): Y376‑p, LYN (rat): Y397‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S1943-p - MYH9 (human)
Modsite: RKGAGDGsDEEVDGK SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): S1943‑p, MYH9 iso2 (human): S1365‑p, MYH9 (mouse): S1943‑p, MYH9 (rat): S1944‑p, MYH9 (cow): S1942‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T366-p - NDRG1 (human)
Modsite: GtRsRsHtsEGAHLD SwissProt Entrez-Gene
Orthologous residues
NDRG1 (human): T366‑p, NDRG1 iso2 (human): T300‑p, NDRG1 iso3 (human): T285‑p, NDRG1 (mouse): T366‑p, NDRG1 (rat): T366‑p, NDRG1 (cow): T356‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

T180-p - P38A (human)
Modsite: RHtDDEMtGyVAtRW SwissProt Entrez-Gene
Orthologous residues
P38A (human): T180‑p, P38A iso2 (human): T180‑p, P38A (mouse): T180‑p, P38A iso3 (mouse): T180‑p, P38A (rat): T180‑p, P38A (salmonid): T181‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38B (human)
Modsite: ADEEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38B (human): Y182‑p, P38B (mouse): Y182‑p, P38B (rat): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S116-p - PEA-15 (human)
Modsite: kDIIRQPsEEEIIKL SwissProt Entrez-Gene
Orthologous residues
PEA‑15 (human): S116‑p, PEA‑15 (mouse): S116‑p, PEA‑15 (rat): S116‑p, PEA‑15 (hamster): S116‑p, PEA‑15 (cow): S116‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y753-p - PLCG2 (human)
Modsite: ERDINSLyDVsRMyV SwissProt Entrez-Gene
Orthologous residues
PLCG2 (human): Y753‑p, PLCG2 (mouse): Y753‑p, PLCG2 (rat): Y753‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y759-p - PLCG2 (human)
Modsite: LyDVsRMyVDPsEIN SwissProt Entrez-Gene
Orthologous residues
PLCG2 (human): Y759‑p, PLCG2 (mouse): Y759‑p, PLCG2 (rat): Y759‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S250-p - PSMA3 (human)
Modsite: sLkEEDEsDDDNM__ SwissProt Entrez-Gene
Orthologous residues
PSMA3 (human): S250‑p, PSMA3 iso2 (human): S243‑p, PSMA3 (mouse): S250‑p, PSMA3 (rat): S250‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y1165-p - PTPN23 (human)
Modsite: RLIERDPyEHPERLR SwissProt Entrez-Gene
Orthologous residues
PTPN23 (human): Y1165‑p, PTPN23 (mouse): Y1221‑p, PTPN23 (rat): Y1028‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y118-p - PXN (human)
Modsite: VGEEEHVysFPNkQk SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN iso6 (human): Y125‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S119-p - PXN (human)
Modsite: GEEEHVysFPNkQks SwissProt Entrez-Gene
Orthologous residues
PXN (human): S119‑p, PXN iso2 (human): S119‑p, PXN iso3 (human): S119‑p, PXN iso6 (human): S126‑p, PXN (mouse): S119‑p, PXN iso2 (mouse): S119‑p, PXN (rat): S119‑p, PXN (chicken): S119‑p, PXN (cow): S113‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y579-p - Pyk2 (human)
Modsite: RyIEDEDyykAsVTR SwissProt Entrez-Gene
Orthologous residues
Pyk2 (human): Y579‑p, Pyk2 iso2 (human): Y579‑p, Pyk2 (mouse): Y579‑p, Pyk2 (rat): Y579‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y580-p - Pyk2 (human)
Modsite: yIEDEDyykAsVTRL SwissProt Entrez-Gene
Orthologous residues
Pyk2 (human): Y580‑p, Pyk2 iso2 (human): Y580‑p, Pyk2 (mouse): Y580‑p, Pyk2 (rat): Y580‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y36-p - Rin1 (human)
Modsite: kPAQDPLyDVPNAsG SwissProt Entrez-Gene
Orthologous residues
Rin1 (human): Y36‑p, Rin1 iso2 (human): Y36‑p, Rin1 (mouse): Y35‑p, Rin1 (rat): Y35‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S101-p - RPLP1 (human)
Modsite: VEAKKEEsEEsDDDM SwissProt Entrez-Gene
Orthologous residues
RPLP1 (human): S101‑p, RPLP1 (mouse): S101‑p, RPLP1 (rat): S101‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S104-p - RPLP1 (human)
Modsite: KKEEsEEsDDDMGFG SwissProt Entrez-Gene
Orthologous residues
RPLP1 (human): S104‑p, RPLP1 (mouse): S104‑p, RPLP1 (rat): S104‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S102-p - RPLP2 (human)
Modsite: kDEkKEEsEEsDDDM SwissProt Entrez-Gene
Orthologous residues
RPLP2 (human): S102‑p, RPLP2 (mouse): S102‑p, RPLP2 (rat): S102‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S105-p - RPLP2 (human)
Modsite: kKEEsEEsDDDMGFG SwissProt Entrez-Gene
Orthologous residues
RPLP2 (human): S105‑p, RPLP2 (mouse): S105‑p, RPLP2 (rat): S105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S378-p - SH3D19 (human)
Modsite: MDLQKKQsNLATGLs SwissProt Entrez-Gene
Orthologous residues
SH3D19 (human): S378‑p, SH3D19 iso2 (human): S378‑p, SH3D19 (mouse): S377‑p, SH3D19 (rat): C377‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y704-p - STAT3 iso2 (human)
Modsite: ADPGAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y694-p - STAT5A (human)
Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): Y711‑p, STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y699-p - STAT5B (human)
Modsite: tAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5B (human): Y699‑p, STAT5B (mouse): Y699‑p, STAT5B (rat): Y699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y74-p - Syk (human)
Modsite: ERELNGtyAIAGGRT SwissProt Entrez-Gene
Orthologous residues
Syk (human): Y74‑p, Syk iso2 (human): Y74‑p, Syk (mouse): Y73‑p, Syk (rat): Y73‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y352-p - Syk (human)
Modsite: tEVyEsPyADPEEIR SwissProt Entrez-Gene
Orthologous residues
Syk (human): Y352‑p, Syk iso2 (human): Y329‑p, Syk (mouse): Y346‑p, Syk (rat): Y346‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y436-p - talin 1 (human)
Modsite: sTVLQQQyNRVGkVE SwissProt Entrez-Gene
Orthologous residues
talin 1 (human): Y436‑p, talin 1 (mouse): Y436‑p, talin 1 (rat): Y436‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y483-p - tensin 2 (human)
Modsite: GPLDGsPyAQVQRPP SwissProt Entrez-Gene
Orthologous residues
tensin 2 (human): Y483‑p, tensin 2 iso2 (human): Y483‑p, tensin 2 iso4 (human): Y493‑p, tensin 2 (mouse): Y483‑p, tensin 2 (rat): Y483‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA1A (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA1A (human): Y224‑p, TUBA1A (mouse): Y224‑p, TUBA1A (rat): Y224‑p, TUBA1A (cow): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA1B (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA1B (human): Y224‑p, TUBA1B (mouse): Y224‑p, TUBA1B (rat): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA1C (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA1C (human): Y224‑p, TUBA1C (mouse): Y224‑p, TUBA1C (rat): Y224‑p, TUBA1C (cow): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA3C (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA3C (human): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA3E (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA3E (human): Y224‑p, TUBA3E (mouse): Y224‑p, TUBA3E (rat): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA4A (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA4A (human): Y224‑p, TUBA4A (mouse): Y224‑p, TUBA4A (rat): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y224-p - TUBA8 (human)
Modsite: LDIERPtytNLNRLI SwissProt Entrez-Gene
Orthologous residues
TUBA8 (human): Y224‑p, TUBA8 (mouse): Y224‑p, TUBA8 (rat): Y224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

S247-p - TXNDC1 (human)
Modsite: EADEEDVsEEEAEsK SwissProt Entrez-Gene
Orthologous residues
TXNDC1 (human): S247‑p, TXNDC1 (mouse): S245‑p, TXNDC1 (rat): S245‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y61-p - Vimentin (human)
Modsite: AssPGGVyAtrssAV SwissProt Entrez-Gene
Orthologous residues
Vimentin (human): Y61‑p, Vimentin (mouse): Y61‑p, Vimentin (rat): Y61‑p, Vimentin (rabbit): Y61‑p, Vimentin (hamster): Y60‑p, Vimentin (cow): Y61‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y822-p - Vinculin (human)
Modsite: ksFLDsGyRILGAVA SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): Y822‑p, Vinculin iso2 (human): Y822‑p, Vinculin (mouse): Y822‑p, Vinculin (rat): Y822‑p, Vinculin (chicken): Y822‑p, Vinculin (dog): Y822‑p, Vinculin (cow): Y822‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  melanoma skin cancer
Relevant cell lines - cell types - tissues:  skin
Cellular systems studied:  tissue
Species studied:  human