Curated Information
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Home > Curated Information Page > Cst Curation Set #6614
Rikova K (2009) CST Curation Set: 6614; Year: 2009; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S19-p - ABCC5 (human)
Modsite: IPsPGyRsVRERTST SwissProt Entrez-Gene
Orthologous residues
ABCC5 (human): S19‑p, ABCC5 iso2 (human): S19‑p, ABCC5 (mouse): S19‑p, ABCC5 (rat): S19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y413-p - AFAP1L2 (human)
Modsite: DPsPDHLysFRILHK SwissProt Entrez-Gene
Orthologous residues
AFAP1L2 (human): Y413‑p, AFAP1L2 iso2 (human): Y413‑p, AFAP1L2 iso4 (human): Y441‑p, AFAP1L2 (mouse): Y413‑p, AFAP1L2 (rat): Y414‑p, AFAP1L2 (cow): Y413‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S577-p - AKAP1 (human)
Modsite: SGGsDRNsMDsVDsC SwissProt Entrez-Gene
Orthologous residues
AKAP1 (human): S577‑p, AKAP1 (mouse): S531‑p, AKAP1 (rat): S528‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S580-p - AKAP1 (human)
Modsite: sDRNsMDsVDsCCsL SwissProt Entrez-Gene
Orthologous residues
AKAP1 (human): S580‑p, AKAP1 (mouse): S534‑p, AKAP1 (rat): S531‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S583-p - AKAP1 (human)
Modsite: NsMDsVDsCCsLKkt SwissProt Entrez-Gene
Orthologous residues
AKAP1 (human): S583‑p, AKAP1 (mouse): S537‑p, AKAP1 (rat): S534‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S586-p - AKAP1 (human)
Modsite: DsVDsCCsLKktEsF SwissProt Entrez-Gene
Orthologous residues
AKAP1 (human): S586‑p, AKAP1 (mouse): G540‑p, AKAP1 (rat): G537‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S273-p - BTBD1 (human)
Modsite: kVLGkALsLIRFPLM SwissProt Entrez-Gene
Orthologous residues
BTBD1 (human): S273‑p, BTBD1 iso2 (human): S273‑p, BTBD1 (mouse): S279‑p, BTBD1 (rat): S279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T66-p - CDH1 (human)
Modsite: DCTGRQRtAyFsLDT SwissProt Entrez-Gene
Orthologous residues
CDH1 (human): T66‑p, CDH1 (mouse): T68‑p, CDH1 (rat): T70‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y68-p - CDH1 (human)
Modsite: TGRQRtAyFsLDTRF SwissProt Entrez-Gene
Orthologous residues
CDH1 (human): Y68‑p, CDH1 (mouse): F70‑p, CDH1 (rat): F72‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S70-p - CDH1 (human)
Modsite: RQRtAyFsLDTRFKV SwissProt Entrez-Gene
Orthologous residues
CDH1 (human): S70‑p, CDH1 (mouse): S72‑p, CDH1 (rat): S74‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y207-p - CRKL (human)
Modsite: IPEPAHAyAQPQttt SwissProt Entrez-Gene
Orthologous residues
CRKL (human): Y207‑p, CRKL (mouse): Y207‑p, CRKL (rat): Y207‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y382-p - DYRK2 (human)
Modsite: EHQRVytyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK2 (human): Y382‑p, DYRK2 iso2 (human): Y309‑p, DYRK2 (mouse): Y380‑p, DYRK2 (rat): Y308‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y264-p - DYRK4 (human)
Modsite: EHQKVytyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK4 (human): Y264‑p, DYRK4 (mouse): Y379‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y202-p - E2F8 (human)
Modsite: SIGEENKyAEQIMMI SwissProt Entrez-Gene
Orthologous residues
E2F8 (human): Y202‑p, E2F8 (mouse): Y202‑p, E2F8 (rat): Y201‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T421-p - Fes (human)
Modsite: QEREGGRtPtLEILK SwissProt Entrez-Gene
Orthologous residues
Fes (human): T421‑p, Fes (mouse): T421‑p, Fes (rat): T421‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S138-p - FETUA (human)
Modsite: kCDssPDsAEDVrkV SwissProt Entrez-Gene
Orthologous residues
FETUA (human): S138‑p, FETUA (mouse): S138‑p, FETUA (rat): S138‑p, FETUA (cow): S138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S278-p - GSK3A (human)
Modsite: VRGEPNVsyICsRyy SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): S278‑p, GSK3A (mouse): S278‑p, GSK3A (rat): S278‑p, GSK3A (cow): S278‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S215-p - GSK3B (human)
Modsite: VRGEPNVsyICsRyy SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): S215‑p, GSK3B iso2 (human): S215‑p, GSK3B (mouse): S215‑p, GSK3B (rat): S215‑p, GSK3B (rabbit): S215‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y88-p - H4G (human)
Modsite: VTAMAVVyVLKRQGR SwissProt Entrez-Gene
Orthologous residues
H4G (human): Y88‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y25-p - HBA1 (human)
Modsite: VGAHAGEyGAEALER SwissProt Entrez-Gene
Orthologous residues
HBA1 (human): Y25‑p, HBA1 (mouse): Y25‑p, HBA1 (rat): Y25‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S255-p - HSP90B (human)
Modsite: PKIEDVGsDEEDDsG SwissProt Entrez-Gene
Orthologous residues
HSP90B (human): S255‑p, HSP90B (mouse): S255‑p, HSP90B (rat): S255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S892-p - iNOS (human)
Modsite: EFPSLRVsAGFLLsQ SwissProt Entrez-Gene
Orthologous residues
iNOS (human): S892‑p, iNOS (mouse): P886‑p, iNOS (rat): P889‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S898-p - iNOS (human)
Modsite: VsAGFLLsQLPILKP SwissProt Entrez-Gene
Orthologous residues
iNOS (human): S898‑p, iNOS (mouse): S892‑p, iNOS (rat): S895‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S1943-p - MYH9 (human)
Modsite: RKGAGDGsDEEVDGK SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): S1943‑p, MYH9 iso2 (human): S1365‑p, MYH9 (mouse): S1943‑p, MYH9 (rat): S1944‑p, MYH9 (cow): S1942‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T1088-p - ODZ2 (human)
Modsite: SLLKItMtQstVPLN SwissProt Entrez-Gene
Orthologous residues
ODZ2 (human): T1088‑p, ODZ2 (mouse): T1078‑p, ODZ2 (rat): T1088‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

S459-p - RBM28 (human)
Modsite: TKAAEGVsAADMAKR SwissProt Entrez-Gene
Orthologous residues
RBM28 (human): S459‑p, RBM28 (mouse): S449‑p, RBM28 (rat): S453‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y62-p - SHP-2 (human)
Modsite: KIQNtGDyyDLyGGE SwissProt Entrez-Gene
Orthologous residues
SHP‑2 (human): Y62‑p, SHP‑2 iso1 (human): Y62‑p, SHP‑2 (mouse): Y62‑p, SHP‑2 (rat): Y62‑p, SHP‑2 iso1 (rat): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

T726-p - SMARCC2 (human)
Modsite: VEEAAkVtGkADPAF SwissProt Entrez-Gene
Orthologous residues
SMARCC2 (human): T726‑p, SMARCC2 iso2 (human): T757‑p, SMARCC2 iso3 (human): T757‑p, SMARCC2 (mouse): T726‑p, SMARCC2 (rat): T757‑p, SMARCC2 (cow): T757‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human

Y275-p - TKT (human)
Modsite: EQIIQEIysQIQskk SwissProt Entrez-Gene
Orthologous residues
TKT (human): Y275‑p, TKT iso2 (human): Y283‑p, TKT (mouse): Y275‑p, TKT (rat): Y275‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  human