Zenke FT, King CC, Bohl BP, Bokoch GM (1999) Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. J Biol Chem 274, 32565-73 10551809

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T423-p - PAK1 (human) ▲

Modsite: PEQSkRstMVGtPYW SwissProt Entrez-Gene Orthologous residues PAK1 (human): T423‑p, PAK1 (mouse): T423‑p, PAK1 (rat): T422‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE PAK1 (human) Comments:  autophosphorylation Downstream Regulation Effect of modification (function):  enzymatic activity, induced Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays CDC42 iso1 (human) Induces in vitro