Fu Z, et al. (2006) Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol 26, 8639-54 16954377

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S973-p - BAT3 (human) ▲

Modsite: EPQRENAsPAPGttA SwissProt Entrez-Gene Orthologous residues BAT3 (human): S973‑p, BAT3 iso2 (human): S967‑p, BAT3 iso3 (human): S1003‑p, BAT3 iso5 (human): ‑, BAT3 (mouse): S995‑p, BAT3 (rat): S987‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  HEK293T (epithelial) Cellular systems studied:  cell lines Species studied:  human

T1080-p - BAT3 (human) ▲

Modsite: AAGARPLtsPEsLSR SwissProt Entrez-Gene Orthologous residues BAT3 (human): T1080‑p, BAT3 iso2 (human): T1074‑p, BAT3 iso3 (human): T1110‑p, BAT3 iso5 (human): ‑, BAT3 (mouse): T1102‑p, BAT3 (rat): T1094‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  HEK293T (epithelial) Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE ICK (human)

T157-p - ICK (human) ▲

Modsite: IRSKPPytDyVsTRW SwissProt Entrez-Gene Orthologous residues ICK (human): T157‑p, ICK iso2 (human): T157‑p, ICK (mouse): T157‑p, ICK (rat): T157‑p Characterization Methods used to characterize site in vivo:  phospho-antibody Relevant cell lines - cell types - tissues:  HEK293T (epithelial) Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE CDK20 (human) PHOSPHATASE PPP5C (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes PHOSPHATASE PPP5C (human) pharmacological activator of upstream enzyme, transfection of inactive enzyme KINASE CDK20 (human) antisense inhibition of upstream enzyme, transfection of inactive enzyme, phospho-motif antibody Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes H2O2 decrease causes activation of PPP5C and dephosphorylation of T157