Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 12221079
Lin D, et al. (2002) Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels. J Biol Chem 277, 44278-84 12221079
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S4-p - ROMK (human)
Modsite: ____MNAsSRNVFDT SwissProt Entrez-Gene
Orthologous residues
ROMK (human): S4‑p, ROMK (mouse): , ROMK (rat): S4‑p, ROMK iso2 (rat):
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial), COS (fibroblast), oocyte
Cellular systems studied:  cell lines, primary cells
Species studied:  frog, green monkey, human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKCA (human)
Downstream Regulation
Effect of modification (function):  activity, induced, intracellular localization

S183-p - ROMK (human)
Modsite: GAILAKIsRPKKRAK SwissProt Entrez-Gene
Orthologous residues
ROMK (human): S183‑p, ROMK (mouse): S164‑p, ROMK (rat): S183‑p, ROMK iso2 (rat): S164‑p
Downstream Regulation
Effect of modification (function):  activity, induced, intracellular localization

S201-p - ROMK (human)
Modsite: FSKNAVIskRGGKLC SwissProt Entrez-Gene
Orthologous residues
ROMK (human): S201‑p, ROMK (mouse): S182‑p, ROMK (rat): S201‑p, ROMK iso2 (rat): S182‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial), COS (fibroblast), oocyte
Cellular systems studied:  cell lines, primary cells
Species studied:  frog, green monkey, human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKCA (human)
Downstream Regulation
Effect of modification (function):  activity, induced, intracellular localization