Koch T, et al. (2000) Allelic variation S268P of the human mu-opioid receptor affects both desensitization and G protein coupling. Mol Pharmacol 58, 328-34 10908300

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S268-p - MOR-1 (human) ▲

Modsite: LKsVRMLsGsKEKDR SwissProt Entrez-Gene Orthologous residues MOR‑1 (human): S268‑p, MOR‑1 iso5 (human): S268‑p, MOR‑1 (mouse): S266‑p, MOR‑1 (rat): S266‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  293 (epithelial), oocyte Cellular systems studied:  cell lines, primary cells Species studied:  frog, human Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CAMK2A (human) modification site within consensus motif, transfection of wild-type enzyme microinjection of kinase protein Downstream Regulation Effect of modification (function):  receptor desensitization, altered

S266-p - MOR-1 (rat) ▲

Modsite: LKsVRMLsGSKEKDR SwissProt Entrez-Gene Orthologous residues MOR‑1 (human): S268‑p, MOR‑1 iso5 (human): S268‑p, MOR‑1 (mouse): S266‑p, MOR‑1 (rat): S266‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  293 (epithelial), oocyte Cellular systems studied:  cell lines, primary cells Species studied:  frog, human Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE CAMK2A (human) modification site within consensus motif, transfection of wild-type enzyme microinjection of kinase protein Downstream Regulation Effect of modification (function):  receptor desensitization, altered