Deng HB, et al. (2000) Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization. Biochemistry 39, 5492-9 10820022

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

T394-p - MOR-1 (rat) ▲

Modsite: LENLEAEtAPLP___ SwissProt Entrez-Gene Orthologous residues MOR‑1 (human): T396‑p, MOR‑1 iso5 (human): M395‑p, MOR‑1 (mouse): T394‑p, MOR‑1 (rat): T394‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, western blotting Relevant cell lines - cell types - tissues:  CHO (fibroblast) Cellular systems studied:  cell lines Species studied:  hamster Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes DAMGO increase wild-type DAMGO inhibit treatment-induced increase T394A mutant Downstream Regulation Effect of modification (function):  receptor desensitization, altered Comments:  in vitro adenylyl cyclase inhibition