Curated Information
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Home > Curated Information Page > PubMed Id: 12835205
Yang T, Kanki H, Roden DM (2003) Phosphorylation of the IKs channel complex inhibits drug block: novel mechanism underlying variable antiarrhythmic drug actions. Circulation 108, 132-4 12835205
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S27-p - Kv7.1 (human)
Modsite: LPGARRGsAGLAKKC SwissProt Entrez-Gene
Orthologous residues
Kv7.1 (human): S27‑p, Kv7.1 (mouse): S27‑p, Kv7.1 (rat): S27‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  CHO (fibroblast)
Cellular systems studied:  cell lines
Species studied:  hamster
Downstream Regulation
Effect of modification (function):  activity, induced

S468-p - Kv7.1 (human)
Modsite: yDSsVRKsPtLLEVs SwissProt Entrez-Gene
Orthologous residues
Kv7.1 (human): S468‑p, Kv7.1 (mouse): S467‑p, Kv7.1 (rat): S468‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  CHO (fibroblast)
Cellular systems studied:  cell lines
Species studied:  hamster
Downstream Regulation
Effect of modification (function):  activity, induced

T470-p - Kv7.1 (human)
Modsite: SsVRKsPtLLEVsMP SwissProt Entrez-Gene
Orthologous residues
Kv7.1 (human): T470‑p, Kv7.1 (mouse): T469‑p, Kv7.1 (rat): T470‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  CHO (fibroblast)
Cellular systems studied:  cell lines
Species studied:  hamster
Downstream Regulation
Effect of modification (function):  activity, induced