Curated Information
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Home > Curated Information Page > PubMed Id: 15087422
Quinn KV, Giblin JP, Tinker A (2004) Multisite phosphorylation mechanism for protein kinase A activation of the smooth muscle ATP-sensitive K+ channel. Circ Res 94, 1359-66 15087422
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T633-p - ABCC9 (mouse)
Modsite: FESCKKHtGVQSKPI SwissProt Entrez-Gene
Orthologous residues
ABCC9 (human): T635‑p, ABCC9 iso2 (human): T635‑p, ABCC9 (mouse): T633‑p, ABCC9 (rat): T632‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
Downstream Regulation
Effect of modification (function):  activity, induced

S1465-p - ABCC9 (mouse)
Modsite: RAFVRKSsILIMDEA SwissProt Entrez-Gene
Orthologous residues
ABCC9 (human): S1468‑p, ABCC9 iso2 (human): S1468‑p, ABCC9 (mouse): S1465‑p, ABCC9 (rat): S1464‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
Downstream Regulation
Effect of modification (function):  activity, induced

T234-p - KCNJ8 (rat)
Modsite: IQVVKKTtTPEGEVV SwissProt Entrez-Gene
Orthologous residues
KCNJ8 (human): T234‑p, KCNJ8 (mouse): T234‑p, KCNJ8 (rat): T234‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)

S385-p - KCNJ8 (rat)
Modsite: NsLRKRNsMRRNNsM SwissProt Entrez-Gene
Orthologous residues
KCNJ8 (human): S385‑p, KCNJ8 (mouse): S385‑p, KCNJ8 (rat): S385‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
Downstream Regulation
Effect of modification (function):  activity, induced