Brandon NJ, et al. (2000) GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway. J Biol Chem 275, 38856-62 10978327

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S432-p - GABRB3 (mouse) ▲

Modsite: KTHLRRRssQLKIKI SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S432‑p, GABRB3 iso2 (human): S432‑p, GABRB3 (mouse): S432‑p, GABRB3 (rat): S432‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  A293 ('renal, embryonic'), neuron-'brain, cerebral cortex' Cellular systems studied:  cell lines, primary cells Species studied:  human, rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes colforsin increase

S433-p - GABRB3 (mouse) ▲

Modsite: THLRRRssQLKIKIP SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S433‑p, GABRB3 iso2 (human): S433‑p, GABRB3 (mouse): S433‑p, GABRB3 (rat): S433‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  A293 ('renal, embryonic'), neuron-'brain, cerebral cortex' Cellular systems studied:  cell lines, primary cells Species studied:  human, rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes colforsin increase

S432-p - GABRB3 (rat) ▲

Modsite: KTHLRRRssQLKIKI SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S432‑p, GABRB3 iso2 (human): S432‑p, GABRB3 (mouse): S432‑p, GABRB3 (rat): S432‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  A293 ('renal, embryonic'), neuron-'brain, cerebral cortex' Cellular systems studied:  cell lines, primary cells Species studied:  human, rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase colforsin no change compared to control colforsin, calphostin_C increase

S433-p - GABRB3 (rat) ▲

Modsite: THLRRRssQLKIKIP SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S433‑p, GABRB3 iso2 (human): S433‑p, GABRB3 (mouse): S433‑p, GABRB3 (rat): S433‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  A293 ('renal, embryonic'), neuron-'brain, cerebral cortex' Cellular systems studied:  cell lines, primary cells Species studied:  human, rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase colforsin no change compared to control colforsin, calphostin_C increase