Curated Information
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Home > Curated Information Page > PubMed Id: 28515316
Tomimatsu N, et al. (2017) DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair. J Biol Chem 292, 10779-10790 28515316
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S714-p - EXO1 (human)
Modsite: CNIKLLDsQSDQTSK SwissProt Entrez-Gene
Orthologous residues
EXO1 (human): S714‑p, EXO1 (mouse): N705‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
camptothecin increase
VE822 camptothecin inhibit treatment-induced increase