Curated Information
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Home > Curated Information Page > PubMed Id: 16254239
Webb DJ, et al. (2005) Paxillin phosphorylation sites mapped by mass spectrometry. J Cell Sci 118, 4925-9 16254239
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T29-p - PXN (chicken)
Modsite: PVFLTEEtPySYPTG SwissProt Entrez-Gene
Orthologous residues
PXN (human): T29‑p, PXN iso2 (human): T29‑p, PXN iso3 (human): T29‑p, PXN (mouse): P29‑p, PXN iso2 (mouse): P29‑p, PXN (rat): P29‑p, PXN (chicken): T29‑p, PXN (cow): T24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y31-p - PXN (chicken)
Modsite: FLTEEtPySYPTGNH SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y31‑p, PXN iso2 (human): Y31‑p, PXN iso3 (human): Y31‑p, PXN (mouse): Y31‑p, PXN iso2 (mouse): Y31‑p, PXN (rat): Y31‑p, PXN (chicken): Y31‑p, PXN (cow): Y26‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y40-p - PXN (chicken)
Modsite: YPTGNHTyQEIAVPP SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y40‑p, PXN iso2 (human): Y40‑p, PXN iso3 (human): Y40‑p, PXN (mouse): Y40‑p, PXN iso2 (mouse): Y40‑p, PXN (rat): Y40‑p, PXN (chicken): Y40‑p, PXN (cow): Y35‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y76-p - PXN (chicken)
Modsite: WQPSVSRyGHQQPQs SwissProt Entrez-Gene
Orthologous residues
PXN (human): F76‑p, PXN iso2 (human): F76‑p, PXN iso3 (human): F76‑p, PXN (mouse): Y76‑p, PXN iso2 (mouse): Y76‑p, PXN (rat): Y76‑p, PXN (chicken): Y76‑p, PXN (cow): F70‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S83-p - PXN (chicken)
Modsite: yGHQQPQsQsPIyss SwissProt Entrez-Gene
Orthologous residues
PXN (human): S83‑p, PXN iso2 (human): S83‑p, PXN iso3 (human): S83‑p, PXN (mouse): S83‑p, PXN iso2 (mouse): S83‑p, PXN (rat): S83‑p, PXN (chicken): S83‑p, PXN (cow): S77‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S85-p - PXN (chicken)
Modsite: HQQPQsQsPIysssA SwissProt Entrez-Gene
Orthologous residues
PXN (human): S85‑p, PXN iso2 (human): S85‑p, PXN iso3 (human): S85‑p, PXN (mouse): L85‑p, PXN iso2 (mouse): L85‑p, PXN (rat): S85‑p, PXN (chicken): S85‑p, PXN (cow): S79‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y88-p - PXN (chicken)
Modsite: PQsQsPIysssAKss SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y88‑p, PXN iso2 (human): Y88‑p, PXN iso3 (human): Y88‑p, PXN (mouse): Y88‑p, PXN iso2 (mouse): Y88‑p, PXN (rat): Y88‑p, PXN (chicken): Y88‑p, PXN (cow): Y82‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S89-p - PXN (chicken)
Modsite: QsQsPIysssAKsss SwissProt Entrez-Gene
Orthologous residues
PXN (human): G89‑p, PXN iso2 (human): G89‑p, PXN iso3 (human): G89‑p, PXN (mouse): S89‑p, PXN iso2 (mouse): S89‑p, PXN (rat): S89‑p, PXN (chicken): S89‑p, PXN (cow): G83‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S90-p - PXN (chicken)
Modsite: sQsPIysssAKsssA SwissProt Entrez-Gene
Orthologous residues
PXN (human): S90‑p, PXN iso2 (human): S90‑p, PXN iso3 (human): S90‑p, PXN (mouse): S90‑p, PXN iso2 (mouse): S90‑p, PXN (rat): S90‑p, PXN (chicken): S90‑p, PXN (cow): S84‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S91-p - PXN (chicken)
Modsite: QsPIysssAKsssAs SwissProt Entrez-Gene
Orthologous residues
PXN (human): S91‑p, PXN iso2 (human): S91‑p, PXN iso3 (human): S91‑p, PXN (mouse): S91‑p, PXN iso2 (mouse): S91‑p, PXN (rat): S91‑p, PXN (chicken): S91‑p, PXN (cow): S85‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S94-p - PXN (chicken)
Modsite: IysssAKsssAsVPR SwissProt Entrez-Gene
Orthologous residues
PXN (human): T94‑p, PXN iso2 (human): T94‑p, PXN iso3 (human): T94‑p, PXN (mouse): N94‑p, PXN iso2 (mouse): N94‑p, PXN (rat): N94‑p, PXN (chicken): S94‑p, PXN (cow): T88‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S96-p - PXN (chicken)
Modsite: sssAKsssAsVPRDG SwissProt Entrez-Gene
Orthologous residues
PXN (human): S96‑p, PXN iso2 (human): S96‑p, PXN iso3 (human): S96‑p, PXN (mouse): S96‑p, PXN iso2 (mouse): S96‑p, PXN (rat): S96‑p, PXN (chicken): S96‑p, PXN (cow): S90‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S98-p - PXN (chicken)
Modsite: sAKsssAsVPRDGLS SwissProt Entrez-Gene
Orthologous residues
PXN (human): S98‑p, PXN iso2 (human): S98‑p, PXN iso3 (human): S98‑p, PXN (mouse): S98‑p, PXN iso2 (mouse): S98‑p, PXN (rat): S98‑p, PXN (chicken): S98‑p, PXN (cow): S92‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S106-p - PXN (chicken)
Modsite: VPRDGLSsPsPRAsE SwissProt Entrez-Gene
Orthologous residues
PXN (human): S106‑p, PXN iso2 (human): S106‑p, PXN iso3 (human): S106‑p, PXN (mouse): S106‑p, PXN iso2 (mouse): S106‑p, PXN (rat): S106‑p, PXN (chicken): S106‑p, PXN (cow): P100‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S108-p - PXN (chicken)
Modsite: RDGLSsPsPRAsEEE SwissProt Entrez-Gene
Orthologous residues
PXN (human): C108‑p, PXN iso2 (human): C108‑p, PXN iso3 (human): C108‑p, PXN (mouse): C108‑p, PXN iso2 (mouse): C108‑p, PXN (rat): C108‑p, PXN (chicken): S108‑p, PXN (cow): C102‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S112-p - PXN (chicken)
Modsite: SsPsPRAsEEEHVys SwissProt Entrez-Gene
Orthologous residues
PXN (human): G112‑p, PXN iso2 (human): G112‑p, PXN iso3 (human): G112‑p, PXN (mouse): G112‑p, PXN iso2 (mouse): G112‑p, PXN (rat): G112‑p, PXN (chicken): S112‑p, PXN (cow): G106‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y118-p - PXN (chicken)
Modsite: AsEEEHVysFPNKQK SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S119-p - PXN (chicken)
Modsite: sEEEHVysFPNKQKs SwissProt Entrez-Gene
Orthologous residues
PXN (human): S119‑p, PXN iso2 (human): S119‑p, PXN iso3 (human): S119‑p, PXN (mouse): S119‑p, PXN iso2 (mouse): S119‑p, PXN (rat): S119‑p, PXN (chicken): S119‑p, PXN (cow): S113‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S126-p - PXN (chicken)
Modsite: sFPNKQKsAEPsPTM SwissProt Entrez-Gene
Orthologous residues
PXN (human): S126‑p, PXN iso2 (human): S126‑p, PXN iso3 (human): S126‑p, PXN (mouse): S126‑p, PXN iso2 (mouse): S126‑p, PXN (rat): S126‑p, PXN (chicken): S126‑p, PXN (cow): S120‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S130-p - PXN (chicken)
Modsite: KQKsAEPsPTMTSTs SwissProt Entrez-Gene
Orthologous residues
PXN (human): S130‑p, PXN iso2 (human): S130‑p, PXN iso3 (human): S130‑p, PXN (mouse): S130‑p, PXN iso2 (mouse): S130‑p, PXN (rat): S130‑p, PXN (chicken): S130‑p, PXN (cow): S124‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S137-p - PXN (chicken)
Modsite: sPTMTSTsLGSNLsE SwissProt Entrez-Gene
Orthologous residues
PXN (human): S137‑p, PXN iso2 (human): S137‑p, PXN iso3 (human): S137‑p, PXN (mouse): S137‑p, PXN iso2 (mouse): S137‑p, PXN (rat): S137‑p, PXN (chicken): S137‑p, PXN (cow): S131‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S143-p - PXN (chicken)
Modsite: TsLGSNLsELDRLLL SwissProt Entrez-Gene
Orthologous residues
PXN (human): S143‑p, PXN iso2 (human): S143‑p, PXN iso3 (human): S143‑p, PXN (mouse): S143‑p, PXN iso2 (mouse): S143‑p, PXN (rat): S143‑p, PXN (chicken): S143‑p, PXN (cow): S137‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S164-p - PXN (chicken)
Modsite: HNPPSGFsADEVSRs SwissProt Entrez-Gene
Orthologous residues
PXN (human): , PXN iso2 (human): , PXN iso3 (human): , PXN (mouse): , PXN iso2 (mouse): , PXN (rat): S163‑p, PXN (chicken): S164‑p, PXN (cow):
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S171-p - PXN (chicken)
Modsite: sADEVSRsPsLPNVT SwissProt Entrez-Gene
Orthologous residues
PXN (human): S170‑p, PXN iso2 (human): S170‑p, PXN iso3 (human): S170‑p, PXN (mouse): S170‑p, PXN iso2 (mouse): S170‑p, PXN (rat): S199‑p, PXN (chicken): S171‑p, PXN (cow): S164‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S173-p - PXN (chicken)
Modsite: DEVSRsPsLPNVTGP SwissProt Entrez-Gene
Orthologous residues
PXN (human): P172‑p, PXN iso2 (human): P172‑p, PXN iso3 (human): P172‑p, PXN (mouse): P172‑p, PXN iso2 (mouse): P172‑p, PXN (rat): P201‑p, PXN (chicken): S173‑p, PXN (cow): P166‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y182-p - PXN (chicken)
Modsite: PNVTGPHyVIPEsss SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y181‑p, PXN iso2 (human): Y181‑p, PXN iso3 (human): Y181‑p, PXN (mouse): Y181‑p, PXN iso2 (mouse): Y181‑p, PXN (rat): Y210‑p, PXN (chicken): Y182‑p, PXN (cow): Y175‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

T199-p - PXN (chicken)
Modsite: GGKAAPPtKEKPKRN SwissProt Entrez-Gene
Orthologous residues
PXN (human): T198‑p, PXN iso2 (human): T198‑p, PXN iso3 (human): T198‑p, PXN (mouse): V198‑p, PXN iso2 (mouse): V198‑p, PXN (rat): M227‑p, PXN (chicken): T199‑p, PXN (cow): T192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S217-p - PXN (chicken)
Modsite: GIEDVRPsVEsLLDE SwissProt Entrez-Gene
Orthologous residues
PXN (human): S216‑p, PXN iso2 (human): S216‑p, PXN iso3 (human): S216‑p, PXN (mouse): S216‑p, PXN iso2 (mouse): S216‑p, PXN (rat): S245‑p, PXN (chicken): S217‑p, PXN (cow): S210‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  or S220
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S220-p - PXN (chicken)
Modsite: DVRPsVEsLLDELEs SwissProt Entrez-Gene
Orthologous residues
PXN (human): S219‑p, PXN iso2 (human): S219‑p, PXN iso3 (human): S219‑p, PXN (mouse): S219‑p, PXN iso2 (mouse): S219‑p, PXN (rat): S248‑p, PXN (chicken): S220‑p, PXN (cow): N213‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  or S217
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S227-p - PXN (chicken)
Modsite: sLLDELEssVPsPVP SwissProt Entrez-Gene
Orthologous residues
PXN (human): S226‑p, PXN iso2 (human): S226‑p, PXN iso3 (human): S226‑p, PXN (mouse): S226‑p, PXN iso2 (mouse): S226‑p, PXN (rat): N255‑p, PXN (chicken): S227‑p, PXN (cow): S220‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  or S228
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S228-p - PXN (chicken)
Modsite: LLDELEssVPsPVPA SwissProt Entrez-Gene
Orthologous residues
PXN (human): S227‑p, PXN iso2 (human): S227‑p, PXN iso3 (human): S227‑p, PXN (mouse): S227‑p, PXN iso2 (mouse): S227‑p, PXN (rat): S256‑p, PXN (chicken): S228‑p, PXN (cow): S221‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  or S227
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S231-p - PXN (chicken)
Modsite: ELEssVPsPVPAITV SwissProt Entrez-Gene
Orthologous residues
PXN (human): S230‑p, PXN iso2 (human): S230‑p, PXN iso3 (human): S230‑p, PXN (mouse): S230‑p, PXN iso2 (mouse): S230‑p, PXN (rat): S259‑p, PXN (chicken): S231‑p, PXN (cow): S224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S239-p - PXN (chicken)
Modsite: PVPAITVsQGEVSsP SwissProt Entrez-Gene
Orthologous residues
PXN (human): N238‑p, PXN iso2 (human): N238‑p, PXN iso3 (human): N238‑p, PXN (mouse): N238‑p, PXN iso2 (mouse): N238‑p, PXN (rat): N267‑p, PXN (chicken): S239‑p, PXN (cow): N232‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S245-p - PXN (chicken)
Modsite: VsQGEVSsPQRVNAS SwissProt Entrez-Gene
Orthologous residues
PXN (human): S244‑p, PXN iso2 (human): S244‑p, PXN iso3 (human): S244‑p, PXN (mouse): S244‑p, PXN iso2 (mouse): S244‑p, PXN (rat): S273‑p, PXN (chicken): S245‑p, PXN (cow): S238‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S259-p - PXN (chicken)
Modsite: SQQQTRIsASsATRE SwissProt Entrez-Gene
Orthologous residues
PXN (human): S258‑p, PXN iso2 (human): S258‑p, PXN iso3 (human): S258‑p, PXN (mouse): S258‑p, PXN iso2 (mouse): S258‑p, PXN (rat): S287‑p, PXN (chicken): S259‑p, PXN (cow): S252‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S262-p - PXN (chicken)
Modsite: QTRIsASsATRELDE SwissProt Entrez-Gene
Orthologous residues
PXN (human): S261‑p, PXN iso2 (human): S261‑p, PXN iso3 (human): S261‑p, PXN (mouse): S261‑p, PXN iso2 (mouse): S261‑p, PXN (rat): S290‑p, PXN (chicken): S262‑p, PXN (cow): S255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S273-p - PXN (chicken)
Modsite: ELDELMAsLsDFKFM SwissProt Entrez-Gene
Orthologous residues
PXN (human): S272‑p, PXN iso2 (human): S272‑p, PXN iso3 (human): S272‑p, PXN (mouse): S272‑p, PXN iso2 (mouse): S272‑p, PXN (rat): S301‑p, PXN (chicken): S273‑p, PXN (cow): S266‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S275-p - PXN (chicken)
Modsite: DELMAsLsDFKFMAQ SwissProt Entrez-Gene
Orthologous residues
PXN (human): S274‑p, PXN iso2 (human): S274‑p, PXN iso3 (human): S274‑p, PXN (mouse): S274‑p, PXN iso2 (mouse): S274‑p, PXN (rat): S303‑p, PXN (chicken): S275‑p, PXN (cow): S268‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S290-p - PXN (chicken)
Modsite: GKAGGSSsPPSTtPK SwissProt Entrez-Gene
Orthologous residues
PXN (human): S322‑p, PXN iso2 (human): S288‑p, PXN iso3 (human): S336‑p, PXN (mouse): S322‑p, PXN iso2 (mouse): S288‑p, PXN (rat): S317‑p, PXN (chicken): S290‑p, PXN (cow): S317‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

T295-p - PXN (chicken)
Modsite: SSsPPSTtPKPGSQL SwissProt Entrez-Gene
Orthologous residues
PXN (human): P327‑p, PXN iso2 (human): P293‑p, PXN iso3 (human): P341‑p, PXN (mouse): L327‑p, PXN iso2 (mouse): L293‑p, PXN (rat): L322‑p, PXN (chicken): T295‑p, PXN (cow): P322‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S308-p - PXN (chicken)
Modsite: QLDTMLGsLQSDLNK SwissProt Entrez-Gene
Orthologous residues
PXN (human): S340‑p, PXN iso2 (human): S306‑p, PXN iso3 (human): S354‑p, PXN (mouse): S340‑p, PXN iso2 (mouse): S306‑p, PXN (rat): S335‑p, PXN (chicken): S308‑p, PXN (cow): S335‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

T344-p - PXN (chicken)
Modsite: VVTAMGKtWHPEHFV SwissProt Entrez-Gene
Orthologous residues
PXN (human): T376‑p, PXN iso2 (human): T342‑p, PXN iso3 (human): T390‑p, PXN (mouse): T376‑p, PXN iso2 (mouse): T342‑p, PXN (rat): T371‑p, PXN (chicken): T344‑p, PXN (cow): T371‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S361-p - PXN (chicken)
Modsite: HCQEEIGsRNFFERD SwissProt Entrez-Gene
Orthologous residues
PXN (human): S393‑p, PXN iso2 (human): S359‑p, PXN iso3 (human): S407‑p, PXN (mouse): S393‑p, PXN iso2 (mouse): S359‑p, PXN (rat): S388‑p, PXN (chicken): S361‑p, PXN (cow): S388‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y377-p - PXN (chicken)
Modsite: QPYCEKDyHNLFsPR SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y409‑p, PXN iso2 (human): Y375‑p, PXN iso3 (human): Y423‑p, PXN (mouse): Y409‑p, PXN iso2 (mouse): Y375‑p, PXN (rat): Y404‑p, PXN (chicken): Y377‑p, PXN (cow): Y404‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S382-p - PXN (chicken)
Modsite: KDyHNLFsPRCYYCN SwissProt Entrez-Gene
Orthologous residues
PXN (human): S414‑p, PXN iso2 (human): S380‑p, PXN iso3 (human): S428‑p, PXN (mouse): S414‑p, PXN iso2 (mouse): S380‑p, PXN (rat): S409‑p, PXN (chicken): S382‑p, PXN (cow): S409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

T403-p - PXN (chicken)
Modsite: VVtALDRtWHPEHFF SwissProt Entrez-Gene
Orthologous residues
PXN (human): T435‑p, PXN iso2 (human): T401‑p, PXN iso3 (human): T449‑p, PXN (mouse): T435‑p, PXN iso2 (mouse): T401‑p, PXN (rat): T430‑p, PXN (chicken): T403‑p, PXN (cow): T430‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

Y436-p - PXN (chicken)
Modsite: KAYCRKDyFDMFAPK SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y468‑p, PXN iso2 (human): Y434‑p, PXN iso3 (human): Y482‑p, PXN (mouse): Y468‑p, PXN iso2 (mouse): Y434‑p, PXN (rat): Y463‑p, PXN (chicken): Y436‑p, PXN (cow): Y463‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S501-p - PXN (chicken)
Modsite: HYHERRGsLCsGCQK SwissProt Entrez-Gene
Orthologous residues
PXN (human): S533‑p, PXN iso2 (human): S499‑p, PXN iso3 (human): S547‑p, PXN (mouse): S533‑p, PXN iso2 (mouse): S499‑p, PXN (rat): S528‑p, PXN (chicken): S501‑p, PXN (cow): S528‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

S504-p - PXN (chicken)
Modsite: ERRGsLCsGCQKPIT SwissProt Entrez-Gene
Orthologous residues
PXN (human): S536‑p, PXN iso2 (human): S502‑p, PXN iso3 (human): S550‑p, PXN (mouse): S536‑p, PXN iso2 (mouse): S502‑p, PXN (rat): S531‑p, PXN (chicken): S504‑p, PXN (cow): S531‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase

T540-p - PXN (chicken)
Modsite: LKQLNKGtFKEQNDK SwissProt Entrez-Gene
Orthologous residues
PXN (human): T572‑p, PXN iso2 (human): T538‑p, PXN iso3 (human): T586‑p, PXN (mouse): T572‑p, PXN iso2 (mouse): T538‑p, PXN (rat): T567‑p, PXN (chicken): T540‑p, PXN (cow): T567‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
calyculin_A, vanadate increase