Curated Information
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Home > Curated Information Page > PubMed Id: 16622009
Potter RM, Maestas DC, Cimino DF, Prossnitz ER (2006) Regulation of N-formyl peptide receptor signaling and trafficking by individual carboxyl-terminal serine and threonine residues. J Immunol 176, 5418-25 16622009
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S328-p - FPR1 (human)
Modsite: ERALtEDstQtsDtA SwissProt Entrez-Gene
Orthologous residues
FPR1 (human): S328‑p, FPR1 (mouse): S339‑p, FPR1 (rat): S332‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  U-937 (myeloid)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  molecular association, regulation, receptor desensitization, altered, receptor internalization, altered
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
ARRB2 (human) Induces co-immunoprecipitation

S332-p - FPR1 (human)
Modsite: tEDstQtsDtAtNst SwissProt Entrez-Gene
Orthologous residues
FPR1 (human): S332‑p, FPR1 (mouse): S343‑p, FPR1 (rat): S336‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  U-937 (myeloid)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  molecular association, regulation, receptor desensitization, altered, receptor internalization, altered
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
ARRB2 (human) Induces co-immunoprecipitation

S338-p - FPR1 (human)
Modsite: tsDtAtNstLPsAEV SwissProt Entrez-Gene
Orthologous residues
FPR1 (human): S338‑p, FPR1 (mouse): L349‑p, FPR1 (rat): L342‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  U-937 (myeloid)
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  molecular association, regulation, receptor desensitization, altered, receptor internalization, altered
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
ARRB2 (human) Induces co-immunoprecipitation