Curated Information
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Home > Curated Information Page > PubMed Id: 17332413
Tenoever BR, et al. (2007) Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science 315, 1274-8 17332413
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S708-p - STAT1 (mouse)
Modsite: yIkTELIsVSEVHPS SwissProt Entrez-Gene
Orthologous residues
STAT1 (human): S708‑p, STAT1 iso2 (human): S708‑p, STAT1 (mouse): S708‑p, STAT1 (rat): S708‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  fibroblast-embryo
Cellular systems studied:  primary cultured cells
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE IKKE (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
IFN-beta increase

S744-p - STAT1 (mouse)
Modsite: IVGPEFDsMMsTV__ SwissProt Entrez-Gene
Orthologous residues
STAT1 (human): S745‑p, STAT1 iso2 (human): , STAT1 (mouse): S744‑p, STAT1 (rat): S744‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  fibroblast-embryo
Cellular systems studied:  primary cultured cells
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE IKKE (human)

S747-p - STAT1 (mouse)
Modsite: PEFDsMMsTV_____ SwissProt Entrez-Gene
Orthologous residues
STAT1 (human): N748‑p, STAT1 iso2 (human): , STAT1 (mouse): S747‑p, STAT1 (rat): S747‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  fibroblast-embryo
Cellular systems studied:  primary cultured cells
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE IKKE (human)