Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 16301179
Gao J, et al. (2005) Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 48, 635-46 16301179
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

S476-p - ASIC1 (rat)
Modsite: CQKEAKRssADKGVA SwissProt Entrez-Gene
Orthologous residues
ASIC1 (human): S478‑p, ASIC1 iso1 (human): S524‑p, ASIC1 iso3 (human): S512‑p, ASIC1 (mouse): N476‑p, ASIC1 (rat): S476‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'neuron, hippocampal'-brain
Cellular systems studied:  primary cells
Species studied:  rat
Enzymes shown to modify site in vitro
Type Enzyme
KINASE CAMK2A (rat)
Downstream Regulation
Effect of modification (function):  activity, inhibited
Effect of modification (process):  apoptosis, altered

S477-p - ASIC1 (rat)
Modsite: QKEAKRssADKGVAL SwissProt Entrez-Gene
Orthologous residues
ASIC1 (human): S479‑p, ASIC1 iso1 (human): S525‑p, ASIC1 iso3 (human): S513‑p, ASIC1 (mouse): S477‑p, ASIC1 (rat): S477‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'neuron, hippocampal'-brain
Cellular systems studied:  primary cells
Species studied:  rat
Enzymes shown to modify site in vitro
Type Enzyme
KINASE CAMK2A (rat)
Downstream Regulation
Effect of modification (function):  activity, inhibited
Effect of modification (process):  apoptosis, altered