Curated Information
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Home > Curated Information Page > PubMed Id: 19272359
Palminiello S, et al. (2009) Upregulation of phosphorylated alphaB-crystallin in the brain of children and young adults with Down syndrome. Brain Res 1268, 162-73 19272359
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S45-p - CRYAB (human)
Modsite: FPTSTsLsPFYLrPP SwissProt Entrez-Gene
Orthologous residues
CRYAB (human): S45‑p, CRYAB (mouse): S45‑p, CRYAB (rat): S45‑p, CRYAB (rabbit): S45‑p, CRYAB (pig): S45‑p, CRYAB (cow): S45‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Disease tissue studied:  Down syndrome
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  human
Associated Diseases
Diseases Alterations Comments
Down syndrome increased in the brain tissues isolated from children and young adults

S59-p - CRYAB (human)
Modsite: PsFLRAPsWFDTGLS SwissProt Entrez-Gene
Orthologous residues
CRYAB (human): S59‑p, CRYAB (mouse): S59‑p, CRYAB (rat): S59‑p, CRYAB (rabbit): S59‑p, CRYAB (pig): S59‑p, CRYAB (cow): S59‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Disease tissue studied:  Down syndrome
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  human
Associated Diseases
Diseases Alterations Comments
Down syndrome increased in the brain tissues isolated from children and young adults