Curated Information
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Home > Curated Information Page > PubMed Id: 16270749
Klinz FJ, et al. (2005) Phospho-eNOS Ser-114 in human mesenchymal stem cells: constitutive phosphorylation, nuclear localization and upregulation during mitosis. Eur J Cell Biol 84, 809-18 16270749
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S114-p - eNOS (human)
Modsite: RKLQGRPsPGPPAPE SwissProt Entrez-Gene
Orthologous residues
eNOS (human): S114‑p, eNOS (mouse): T113‑p, eNOS (rat): T113‑p, eNOS (rabbit): T120‑p, eNOS (pig): S116‑p, eNOS (cow): S116‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  stromal
Cellular systems studied:  primary cells
Species studied:  human
Comments:  bone marrow-derived stromal cells
Downstream Regulation
Effect of modification (function):  intracellular localization
Comments:  Phosphorylated S113 is enriched in the nucleus and is increased during mitosis. It is colocalized with 8-hydroxyguanisine.

S1177-p - eNOS (human)
Modsite: TSRIRtQsFsLQERQ SwissProt Entrez-Gene
Orthologous residues
eNOS (human): S1177‑p, eNOS (mouse): S1176‑p, eNOS (rat): S1176‑p, eNOS (rabbit): S1183‑p, eNOS (pig): S1179‑p, eNOS (cow): S1179‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  stromal
Cellular systems studied:  primary cells
Species studied:  human
Comments:  bone marrow-derived stromal cells
Downstream Regulation
Effect of modification (function):  intracellular localization
Comments:  Phosphorylated S114 is localized at perinuclear filamentous structures in the cytosol.