Curated Information
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Home > Curated Information Page > PubMed Id: 16097034
Gevaert K, et al. (2005) Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. Proteomics 5, 3589-99 16097034
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T7083-p - ACF7 (human)
Modsite: PTTKLEMtAVADIFD SwissProt Entrez-Gene
Orthologous residues
ACF7 (human): T7083‑p, ACF7 iso2 (human): T5125‑p, ACF7 iso3 (human): T5069‑p, ACF7 iso6 (human): T107‑p, ACF7 (mouse): T7043‑p, ACF7 iso4 (mouse): T5167‑p, ACF7 iso7 (mouse): T5028‑p, ACF7 (rat): T7040‑p, ACF7 iso2 (rat): T5125‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T50-p - ACTN1 (human)
Modsite: SHLRKAGtQIENIEE SwissProt Entrez-Gene
Orthologous residues
ACTN1 (human): T50‑p, ACTN1 iso2 (human): T50‑p, ACTN1 (mouse): T50‑p, ACTN1 iso3 (mouse): T50‑p, ACTN1 (rat): T50‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T65-p - ALDOA (human)
Modsite: FYRQLLLtADDrVNP SwissProt Entrez-Gene
Orthologous residues
ALDOA (human): T65‑p, ALDOA (mouse): T65‑p, ALDOA (rat): T65‑p, ALDOA (rabbit): T65‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S115-p - COTL1 (human)
Modsite: FAkEFVIsDrKELEE SwissProt Entrez-Gene
Orthologous residues
COTL1 (human): S115‑p, COTL1 (mouse): S115‑p, COTL1 (rat): S115‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S571-p - CTPS (human)
Modsite: RDtysDrsGsssPDs SwissProt Entrez-Gene
Orthologous residues
CTPS (human): S571‑p, CTPS (mouse): S571‑p, CTPS (rat): S571‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S573-p - CTPS (human)
Modsite: tysDrsGsssPDsEI SwissProt Entrez-Gene
Orthologous residues
CTPS (human): S573‑p, CTPS (mouse): S573‑p, CTPS (rat): S573‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S574-p - CTPS (human)
Modsite: ysDrsGsssPDsEIt SwissProt Entrez-Gene
Orthologous residues
CTPS (human): S574‑p, CTPS (mouse): S574‑p, CTPS (rat): S574‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y321-p - DDX17 (human)
Modsite: TNLRRCTyLVLDEAD SwissProt Entrez-Gene
Orthologous residues
DDX17 (human): Y321‑p, DDX17 iso1 (human): Y242‑p, DDX17 iso3 (human): Y242‑p, DDX17 (mouse): Y242‑p, DDX17 iso4 (mouse): Y242‑p, DDX17 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y343-p - DDX3 (human)
Modsite: IGLDFCkyLVLDEAD SwissProt Entrez-Gene
Orthologous residues
DDX3 (human): Y343‑p, DDX3 iso2 (human): Y327‑p, DDX3 (mouse): Y343‑p, DDX3 (rat): Y343‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y341-p - DDX3Y (human)
Modsite: IGLDFCkyLVLDEAD SwissProt Entrez-Gene
Orthologous residues
DDX3Y (human): Y341‑p, DDX3Y iso2 (human): Y338‑p, DDX3Y (mouse): Y342‑p, DDX3Y (rat): Y336‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y244-p - DDX5 (human)
Modsite: TNLRRTtyLVLDEAD SwissProt Entrez-Gene
Orthologous residues
DDX5 (human): Y244‑p, DDX5 (mouse): Y244‑p, DDX5 (rat): Y244‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T425-p - DPP3 (human)
Modsite: ATQREKLtFLEEDDK SwissProt Entrez-Gene
Orthologous residues
DPP3 (human): T425‑p, DPP3 (mouse): T425‑p, DPP3 (rat): T425‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S162-p - EEF1D (human)
Modsite: DDIDLFGsDNEEEDK SwissProt Entrez-Gene
Orthologous residues
EEF1D (human): S162‑p, EEF1D iso2 (human): S528‑p, EEF1D iso4 (human): S143‑p, EEF1D iso5 (human): S431‑p, EEF1D iso6 (human): , EEF1D (mouse): S162‑p, EEF1D iso2 (mouse): S138‑p, EEF1D iso3 (mouse): S541‑p, EEF1D iso4 (mouse): S157‑p, EEF1D (rat): S531‑p, EEF1D (rabbit): S162‑p, EEF1D (cow): S519‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y978-p - EGFR (human)
Modsite: MARDPQRyLVIQGDE SwissProt Entrez-Gene
Orthologous residues
EGFR (human): Y978‑p, EGFR iso2 (human): , EGFR iso5 (human): Y978‑p, EGFR (mouse): Y980‑p, EGFR (rat): Y979‑p, EGFR (pig): Y978‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S544-p - eIF2B-epsilon (human)
Modsite: EPDsRGGsPQMDDIK SwissProt Entrez-Gene
Orthologous residues
eIF2B‑epsilon (human): S544‑p, eIF2B‑epsilon (mouse): S540‑p, eIF2B‑epsilon (rat): S539‑p, eIF2B‑epsilon (rabbit): S544‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S39-p - EIF3C (human)
Modsite: GKQPLLLsEDEEDtK SwissProt Entrez-Gene
Orthologous residues
EIF3C (human): S39‑p, EIF3C (mouse): S39‑p, EIF3C (rat): S39‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S135-p - EIF5B (human)
Modsite: KPKVEMysGsDDDDD SwissProt Entrez-Gene
Orthologous residues
EIF5B (human): S135‑p, EIF5B (mouse): S137‑p, EIF5B (rat): S137‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S137-p - EIF5B (human)
Modsite: KVEMysGsDDDDDFN SwissProt Entrez-Gene
Orthologous residues
EIF5B (human): S137‑p, EIF5B (mouse): S139‑p, EIF5B (rat): S139‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S20-p - GM130 (human)
Modsite: MSEETRQsKLAAAKK SwissProt Entrez-Gene
Orthologous residues
GM130 (human): S20‑p, GM130 iso3 (human): S20‑p, GM130 (mouse): S20‑p, GM130 iso2 (mouse): S20‑p, GM130 iso3 (mouse): S20‑p, GM130 (rat): S20‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S217-p - GTF2F1 (human)
Modsite: LEDDLEMssDAsDAs SwissProt Entrez-Gene
Orthologous residues
GTF2F1 (human): S217‑p, GTF2F1 (mouse): S217‑p, GTF2F1 (rat): S217‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S218-p - GTF2F1 (human)
Modsite: EDDLEMssDAsDAsG SwissProt Entrez-Gene
Orthologous residues
GTF2F1 (human): S218‑p, GTF2F1 (mouse): S218‑p, GTF2F1 (rat): S218‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S221-p - GTF2F1 (human)
Modsite: LEMssDAsDAsGEEG SwissProt Entrez-Gene
Orthologous residues
GTF2F1 (human): S221‑p, GTF2F1 (mouse): S221‑p, GTF2F1 (rat): S221‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S224-p - GTF2F1 (human)
Modsite: ssDAsDAsGEEGGRV SwissProt Entrez-Gene
Orthologous residues
GTF2F1 (human): S224‑p, GTF2F1 (mouse): S224‑p, GTF2F1 (rat): S224‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y83-p - HLAC (human)
Modsite: VEQEGPEyWDRETQK SwissProt Entrez-Gene
Orthologous residues
HLAC (human): Y83‑p, HLAC iso2 (human): Y83‑p, HLAC iso5 (human): Y83‑p, HLAC iso6 (human): Y83‑p, HLAC iso7 (human): Y83‑p, HLAC iso14 (human): Y83‑p, HLAC (mouse): Y83‑p, HLAC iso8 (mouse): Y80‑p, HLAC iso25 (mouse): Y80‑p, HLAC iso27 (mouse): Y80‑p, HLAC (rat): Y59‑p, HLAC iso1 (rat): Y83‑p, HLAC iso3 (rat): Y80‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T138-p - hnRNP A1 (human)
Modsite: IEVIEIMtDrGsGkk SwissProt Entrez-Gene
Orthologous residues
hnRNP A1 (human): T138‑p, hnRNP A1 iso2 (human): T138‑p, hnRNP A1 (mouse): T138‑p, hnRNP A1 iso2 (mouse): T138‑p, hnRNP A1 (rat): T138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S82-p - HSP27 (human)
Modsite: RALsRQLssGVsEIr SwissProt Entrez-Gene
Orthologous residues
HSP27 (human): S82‑p, HSP27 (mouse): S86‑p, HSP27 (rat): S86‑p, HSP27 (pig): S84‑p, HSP27 (hamster): S90‑p, HSP27 (chicken): S80‑p, HSP27 (dog): S86‑p, HSP27 (cow): S78‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S222-p - Ku70 (human)
Modsite: LFYRDIIsIAEDEDL SwissProt Entrez-Gene
Orthologous residues
Ku70 (human): S222‑p, Ku70 (mouse): T220‑p, Ku70 (rat): S220‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S1213-p - MYO5A (human)
Modsite: LkRQELEsENKKLKN SwissProt Entrez-Gene
Orthologous residues
MYO5A (human): S1213‑p, MYO5A iso2 (human): S1213‑p, MYO5A iso3 (human): S1213‑p, MYO5A (mouse): S1213‑p, MYO5A (rat): S1213‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S149-p - NKAP (human)
Modsite: APEVWGLsPkNPEPD SwissProt Entrez-Gene
Orthologous residues
NKAP (human): S149‑p, NKAP (mouse): S147‑p, NKAP (rat): S147‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S113-p - NUCKS (human)
Modsite: MLMEDVGsEEEQEEE SwissProt Entrez-Gene
Orthologous residues
NUCKS (human): S113‑p, NUCKS (mouse): S113‑p, NUCKS (rat): S113‑p, NUCKS (cow): S113‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S63-p - OBTP (human)
Modsite: VWLARNLsDIDLMAP SwissProt Entrez-Gene
Orthologous residues
OBTP (human): S63‑p, OBTP (mouse): S63‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T188-p - peptidase D (human)
Modsite: VECRVFKtDMELEVL SwissProt Entrez-Gene
Orthologous residues
peptidase D (human): T188‑p, peptidase D iso3 (human): T124‑p, peptidase D (mouse): T188‑p, peptidase D (rat): T188‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S782-p - Plectin-1 (human)
Modsite: EEVGFDWsDRNTNMT SwissProt Entrez-Gene
Orthologous residues
Plectin‑1 (human): S782‑p, Plectin‑1 iso2 (human): S672‑p, Plectin‑1 iso4 (human): S645‑p, Plectin‑1 iso6 (human): S649‑p, Plectin‑1 iso9 (human): S631‑p, Plectin‑1 (mouse): S790‑p, Plectin‑1 iso3 (mouse): S642‑p, Plectin‑1 iso6 (mouse): S671‑p, Plectin‑1 (rat): S785‑p, Plectin‑1 iso2 (rat): S642‑p, Plectin‑1 (cow): S772‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T157-p - PPIA (human)
Modsite: GkTSKkItIADCGQL SwissProt Entrez-Gene
Orthologous residues
PPIA (human): T157‑p, PPIA (mouse): T157‑p, PPIA (rat): T157‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y49-p - PSMD1 (human)
Modsite: VDKIEVLyEDEGFRS SwissProt Entrez-Gene
Orthologous residues
PSMD1 (human): Y49‑p, PSMD1 iso2 (human): Y49‑p, PSMD1 (mouse): Y49‑p, PSMD1 (rat): Y49‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S104-p - RPLP1 (human)
Modsite: KKEEsEEsDDDMGFG SwissProt Entrez-Gene
Orthologous residues
RPLP1 (human): S104‑p, RPLP1 (mouse): S104‑p, RPLP1 (rat): S104‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T838-p - SETDB1 (human)
Modsite: IYAGKILtDDFADKE SwissProt Entrez-Gene
Orthologous residues
SETDB1 (human): T838‑p, SETDB1 iso3 (human): T838‑p, SETDB1 (mouse): T855‑p, SETDB1 (rat): T850‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T507-p - SLC7A5 (human)
Modsite: MQVVPQEt_______ SwissProt Entrez-Gene
Orthologous residues
SLC7A5 (human): T507‑p, SLC7A5 (mouse): T512‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S1568-p - SMARCA2 (human)
Modsite: GKAKPVVsDFDsDEE SwissProt Entrez-Gene
Orthologous residues
SMARCA2 (human): S1568‑p, SMARCA2 iso2 (human): S1550‑p, SMARCA2 (mouse): S1555‑p, SMARCA2 (rat): S1575‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S1572-p - SMARCA2 (human)
Modsite: PVVsDFDsDEEQDER SwissProt Entrez-Gene
Orthologous residues
SMARCA2 (human): S1572‑p, SMARCA2 iso2 (human): S1554‑p, SMARCA2 (mouse): S1559‑p, SMARCA2 (rat): S1579‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S2-p - TRA2A (human)
Modsite: ______MsDVEENNF SwissProt Entrez-Gene
Orthologous residues
TRA2A (human): S2‑p, TRA2A (mouse): S2‑p, TRA2A (rat): S2‑p, TRA2A (cow): S2‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T100-p - TXN (human)
Modsite: NkEkLEAtINELV__ SwissProt Entrez-Gene
Orthologous residues
TXN (human): T100‑p, TXN (mouse): S100‑p, TXN (rat): T100‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

S2-p - U2AF2 (human)
Modsite: ______MsDFDEFER SwissProt Entrez-Gene
Orthologous residues
U2AF2 (human): S2‑p, U2AF2 iso2 (human): S2‑p, U2AF2 (mouse): S2‑p, U2AF2 (rat): S2‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T508-p - Vinculin (human)
Modsite: QRWIDNPtVDDrGVG SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): T508‑p, Vinculin iso2 (human): T508‑p, Vinculin (mouse): T508‑p, Vinculin (rat): T508‑p, Vinculin (chicken): T508‑p, Vinculin (dog): T508‑p, Vinculin (cow): T508‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

T508-p - Vinculin iso2 (human)
Modsite: QRWIDNPtVDDRGVG SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): T508‑p, Vinculin iso2 (human): T508‑p, Vinculin (mouse): T508‑p, Vinculin (rat): T508‑p, Vinculin (chicken): T508‑p, Vinculin (dog): T508‑p, Vinculin (cow): T508‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  human

Y264-p - EEF2 (rabbit)
Modsite: KKLWGDRyFDPANGK SwissProt
Orthologous residues
EEF2 (human): Y265‑p, EEF2 (mouse): Y265‑p, EEF2 (rat): Y265‑p, EEF2 (rabbit): Y264‑p, EEF2 (cow): Y265‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
Cellular systems studied:  cell lines
Species studied:  rabbit