Curated Information
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Home > Curated Information Page > PubMed Id: 15980066
Harada Y, et al. (2005) Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta. J Biol Chem 280, 31714-21 15980066
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S553-p - CRY2 (mouse)
Modsite: TGPRALSsGPAsPKR SwissProt Entrez-Gene
Orthologous residues
CRY2 (human): S554‑p, CRY2 (mouse): S553‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody
Relevant cell lines - cell types - tissues:  liver
Cellular systems studied:  tissue
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE GSK3B (mouse)
Downstream Regulation
Effect of modification (function):  protein degradation

S557-p - CRY2 (mouse)
Modsite: ALSsGPAsPKRKLEA SwissProt Entrez-Gene
Orthologous residues
CRY2 (human): S558‑p, CRY2 (mouse): S557‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody
Relevant cell lines - cell types - tissues:  liver
Cellular systems studied:  tissue
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE GSK3B (mouse)
Downstream Regulation
Effect of modification (function):  protein degradation

S9-p - GSK3B (mouse)
Modsite: SGRPRttsFAEsCKP SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): S9‑p, GSK3B iso2 (human): S9‑p, GSK3B (mouse): S9‑p, GSK3B (rat): S9‑p, GSK3B (rabbit): S9‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  liver
Cellular systems studied:  tissue
Species studied:  mouse