Curated Information
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Home > Curated Information Page > PubMed Id: 16130142
Dakshinamurti S, Mellow L, Stephens NL (2005) Regulation of pulmonary arterial myosin phosphatase activity in neonatal circulatory transition and in hypoxic pulmonary hypertension: a role for CPI-17. Pediatr Pulmonol 40, 398-407 16130142
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T853-p - MYPT1 (human)
Modsite: PREKRRstGVsFWtQ SwissProt Entrez-Gene
Orthologous residues
MYPT1 (human): T853‑p, MYPT1 iso2 (human): T853‑p, MYPT1 iso3 (human): T797‑p, MYPT1 iso4 (human): T794‑p, MYPT1 (mouse): T852‑p, MYPT1 (rat): T855‑p, MYPT1 (pig): , MYPT1 (chicken): T850‑p, MYPT1 (cow): T851‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  'muscle, smooth'-'heart, artery'
Cellular systems studied:  tissue
Species studied:  pig
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia no change compared to control
development no change compared to control aging after birth

T696-p - MYPT1 (pig)
Modsite: ARQSRRStQGVTLTD SwissProt Entrez-Gene
Orthologous residues
MYPT1 (human): T696‑p, MYPT1 iso2 (human): T696‑p, MYPT1 iso3 (human): T640‑p, MYPT1 iso4 (human): T637‑p, MYPT1 (mouse): T694‑p, MYPT1 (rat): T697‑p, MYPT1 (pig): T696‑p, MYPT1 (chicken): T695‑p, MYPT1 (cow): T696‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  'muscle, smooth'-'heart, artery'
Cellular systems studied:  tissue
Species studied:  pig
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia no change compared to control
development increase aging after birth

T38-p - PPP1R14A (pig)
Modsite: QKRHARVtVKYDRRE SwissProt Entrez-Gene
Orthologous residues
PPP1R14A (human): T38‑p, PPP1R14A iso2 (human): T38‑p, PPP1R14A (mouse): T38‑p, PPP1R14A (rat): T38‑p, PPP1R14A (pig): T38‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  'muscle, smooth'-'heart, artery'
Cellular systems studied:  tissue
Species studied:  pig
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
hypoxia increase
development decrease aging after birth