Maslyar DJ, Aoki M, Vogt PK (2001) The growth-promoting activity of the Bad protein in chicken embryo fibroblasts requires binding to protein 14-3-3. Oncogene 20, 5087-92 11526496

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S473-p - Akt1 (mouse) ▲

Modsite: RPHFPQFsysAsGtA SwissProt Entrez-Gene Orthologous residues Akt1 (human): S473‑p, Akt1 iso2 (human): S411‑p, Akt1 (mouse): S473‑p, Akt1 (rat): S473‑p, Akt1 (fruit fly): S586‑p, Akt1 (cow): S473‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody Relevant cell lines - cell types - tissues:  CEF Cellular systems studied:  cell lines Species studied:  chicken

S112-p - BAD (mouse) ▲
Modsite: ETRsRHssyPAGtEE SwissProt Entrez-Gene Orthologous residues BAD (human): S75‑p, BAD (mouse): S112‑p, BAD (rat): S113‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody Relevant cell lines - cell types - tissues:  CEF Cellular systems studied:  cell lines Species studied:  chicken

S136-p - BAD (mouse) ▲

Modsite: PFRGRsRsAPPNLWA SwissProt Entrez-Gene Orthologous residues BAD (human): S99‑p, BAD (mouse): S136‑p, BAD (rat): S137‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody Relevant cell lines - cell types - tissues:  CEF Cellular systems studied:  cell lines Species studied:  chicken Downstream Regulation Effect of modification (function):  molecular association, regulation Effect of modification (process):  apoptosis, inhibited, cell growth, altered Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays 14-3-3 beta (mouse) Induces co-immunoprecipitation