Curated Information
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Home > Curated Information Page > PubMed Id: 19238206
Ande SR, Moulik S, Mishra S (2009) Interaction between O-GlcNAc Modification and Tyrosine Phosphorylation of Prohibitin: Implication for a Novel Binary Switch. PLoS One 4, e4586 19238206
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y114-p - PHB (human)
Modsite: FtsIGEDyDERVLPs SwissProt Entrez-Gene
Orthologous residues
PHB (human): Y114‑p, PHB (mouse): Y114‑p, PHB (rat): Y114‑p, PHB (pig): Y114‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase
Downstream Regulation
Effect of modification (function):  O-GlcNAc glycosylation

S121-gl - PHB (human)
Modsite: yDERVLPsItTEILk SwissProt Entrez-Gene
Orthologous residues
PHB (human): S121‑gl, PHB (mouse): S121‑gl, PHB (rat): S121‑gl, PHB (pig): S121‑gl
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase
Downstream Regulation
Effect of modification (function):  phosphorylation

T258-gl - PHB (human)
Modsite: LSRSRNItyLPAGQs SwissProt Entrez-Gene
Orthologous residues
PHB (human): T258‑gl, PHB (mouse): T258‑gl, PHB (rat): T258‑gl, PHB (pig): T258‑gl
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase
Downstream Regulation
Effect of modification (function):  phosphorylation

Y259-p - PHB (human)
Modsite: SRSRNItyLPAGQsV SwissProt Entrez-Gene
Orthologous residues
PHB (human): Y259‑p, PHB (mouse): Y259‑p, PHB (rat): Y259‑p, PHB (pig): Y259‑p
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
insulin increase
Downstream Regulation
Effect of modification (function):  O-GlcNAc glycosylation