Curated Information
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Home > Curated Information Page > PubMed Id: 21952047
Zhu J, Coyne CB, Sarkar SN (2011) PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin. EMBO J 30, 4838-49 21952047
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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K49-ac - CTNNB1 (human)
Modsite: TAPsLsGkGNPEEED SwissProt Entrez-Gene
Orthologous residues
CTNNB1 (human): K49‑ac, CTNNB1 (mouse): K49‑ac, CTNNB1 (rat): K49‑ac, CTNNB1 (rabbit): K49‑ac
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
DEACETYLASE HDAC6 (human) pharmacological inhibitor of upstream enzyme, activation of upstream enzyme, transfection of wild-type enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
increase HDAC6 inhibitor CAY10603
virus infection decrease
PKCA (human) decrease siRNA increases
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  transcription, inhibited