Curated Information
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Home > Curated Information Page > PubMed Id: 16096638
Peinado H, et al. (2005) A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression. EMBO J 24, 3446-58 16096638
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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K98-ub - Snail1 (mouse)
Modsite: LSDEDSGkSSQPPSP SwissProt Entrez-Gene
Orthologous residues
Snail1 (human): K98‑ub, Snail1 (mouse): K98‑ub
Downstream Regulation
Effect of modification (function):  molecular association, regulation, protein stabilization
Effect of modification (process):  carcinogenesis, inhibited, transcription, inhibited
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
GSK3B (mouse) Induces co-immunoprecipitation
Comments:  induces EMT

K137-ub - Snail1 (mouse)
Modsite: PGLGQLPkQLARLSV SwissProt Entrez-Gene
Orthologous residues
Snail1 (human): K137‑ub, Snail1 (mouse): K137‑ub
Downstream Regulation
Effect of modification (function):  molecular association, regulation, protein stabilization
Effect of modification (process):  carcinogenesis, inhibited, transcription, inhibited
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
GSK3B (mouse) Induces co-immunoprecipitation
Comments:  induces EMT