Curated Information
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Home > Curated Information Page > PubMed Id: 19091960
Bashari E, et al. (2009) Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function. Am J Physiol Cell Physiol 296, C372-84 19091960
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S40-p - ASIC1 (human)
Modsite: IFSYERLsLKRALWA SwissProt Entrez-Gene
Orthologous residues
ASIC1 (human): S40‑p, ASIC1 iso1 (human): S40‑p, ASIC1 iso3 (human): G86‑p, ASIC1 (mouse): S40‑p, ASIC1 (rat): S40‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase
chelerythrine phorbol_ester inhibit treatment-induced increase
Downstream Regulation
Effect of modification (function):  activity, inhibited

S499-p - ASIC1 (human)
Modsite: kRHNPCEsLRGHPAG SwissProt Entrez-Gene
Orthologous residues
ASIC1 (human): S499‑p, ASIC1 iso1 (human): S545‑p, ASIC1 iso3 (human): S533‑p, ASIC1 (mouse): S497‑p, ASIC1 (rat): S497‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  oocyte
Cellular systems studied:  primary cells
Species studied:  frog
Downstream Regulation
Effect of modification (function):  activity, inhibited