Ren J, Li Y, Kufe D (2002) Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling. J Biol Chem 277, 17616-22 11877440

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T1224-p - MUC1 (human) ▲

Modsite: RyVPPsstDRsPyEK SwissProt Entrez-Gene Orthologous residues MUC1 (human): T1224‑p, MUC1 iso2 (human): T1233‑p, MUC1 iso6 (human): T199‑p, MUC1 iso10 (human): T172‑p, MUC1 (mouse): T599‑p, MUC1 (rat): T43‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  293 (epithelial), HCT116 (intestinal) Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE PKCD (human) Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE PKCD (human) co-immunoprecipitation Downstream Regulation Effect of modification (function):  molecular association, regulation Effect of modification (process):  cell growth, altered