Curated Information
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Home > Curated Information Page > PubMed Id: 27398719
Baruah PS, Beauchemin M, H├ębert J, Bertrand R (2016) Dynamic Bcl-xL (S49) and (S62) Phosphorylation/Dephosphorylation during Mitosis Prevents Chromosome Instability and Aneuploidy in Normal Human Diploid Fibroblasts. PLoS One 11, e0159091 27398719
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S49-p - Bcl-xL (human)
Modsite: ESEMEtPsAINGNPS SwissProt Entrez-Gene
Orthologous residues
Bcl‑xL (human): S49‑p, Bcl‑xL (mouse): S49‑p, Bcl‑xL (rat): S49‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  BJ (fibroblast)
Cellular systems studied:  cell lines
Species studied:  human

S62-p - Bcl-xL (human)
Modsite: PSWHLADsPAVNGAT SwissProt Entrez-Gene
Orthologous residues
Bcl‑xL (human): S62‑p, Bcl‑xL (mouse): S62‑p, Bcl‑xL (rat): S62‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, mutation of modification site, western blotting
Relevant cell lines - cell types - tissues:  BJ (fibroblast)
Cellular systems studied:  cell lines
Species studied:  human