Nanda N, et al. (2005) Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. J Biol Chem 280, 24680-9 15851471

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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Y925-p - PEAR1 (human) ▲

Modsite: SLSSENPyATIRDLP SwissProt Entrez-Gene Orthologous residues PEAR1 (human): Y925‑p, PEAR1 (mouse): Y923‑p, PEAR1 (rat): Y922‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  platelet-blood Cellular systems studied:  primary cells Species studied:  human Comments:  aggregated platelets, induced by TRAP Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes thrombin increase eptifibatide thrombin inhibit treatment-induced increase TRAP increase eptifibatide TRAP inhibit treatment-induced increase collagen increase eptifibatide collagen inhibit treatment-induced increase

S953-p - PEAR1 (human) ▲
Modsite: MKGPPSGsPPRQPPQ SwissProt Entrez-Gene Orthologous residues PEAR1 (human): S953‑p, PEAR1 (mouse): S951‑p, PEAR1 (rat): S950‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  platelet-blood Cellular systems studied:  primary cells Species studied:  human Comments:  aggregated platelets, induced by TRAP

S1029-p - PEAR1 (human) ▲
Modsite: PPVRHPPsPPLRRQD SwissProt Entrez-Gene Orthologous residues PEAR1 (human): S1029‑p, PEAR1 (mouse): S1026‑p, PEAR1 (rat): S1025‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Relevant cell lines - cell types - tissues:  platelet-blood Cellular systems studied:  primary cells Species studied:  human Comments:  aggregated platelets, induced by TRAP