Curated Information
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Home > Curated Information Page > PubMed Id: 20541700
Carretero J, et al. (2010) Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. Cancer Cell 17, 547-59 20541700
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y393-p - Abl (human)
Modsite: RLMtGDtytAHAGAK SwissProt Entrez-Gene
Orthologous residues
Abl (human): Y393‑p, Abl iso2 (human): Y412‑p, Abl (mouse): Y393‑p, Abl iso4 (mouse): Y412‑p, Abl (rat): Y393‑p, Abl iso2 (rat): Y412‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y55-p - ACTA1 (human)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTA1 (human): Y55‑p, ACTA1 (mouse): Y55‑p, ACTA1 (rat): Y55‑p, ACTA1 (rabbit): Y55‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y24-p - ANXA2 (human)
Modsite: HstPPsAyGsVkAyt SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y24‑p, ANXA2 iso2 (human): Y42‑p, ANXA2 (mouse): Y24‑p, ANXA2 (rat): Y24‑p, ANXA2 (dog): Y24‑p, ANXA2 (cow): Y24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y30-p - ANXA2 (human)
Modsite: AyGsVkAytNFDAER SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y30‑p, ANXA2 iso2 (human): Y48‑p, ANXA2 (mouse): Y30‑p, ANXA2 (rat): Y30‑p, ANXA2 (dog): Y30‑p, ANXA2 (cow): Y30‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y702-p - AXL (human)
Modsite: KkIyNGDyyRQGRIA SwissProt Entrez-Gene
Orthologous residues
AXL (human): Y702‑p, AXL iso2 (human): Y693‑p, AXL (mouse): Y696‑p, AXL (rat): Y696‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y707-p - CDCP1 (human)
Modsite: KGPAVGIyNDNINTE SwissProt Entrez-Gene
Orthologous residues
CDCP1 (human): Y707‑p, CDCP1 (mouse): Y705‑p, CDCP1 (rat): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y382-p - DYRK2 (human)
Modsite: EHQRVytyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK2 (human): Y382‑p, DYRK2 iso2 (human): Y309‑p, DYRK2 (mouse): Y380‑p, DYRK2 (rat): Y308‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y525-p - EPS8 (human)
Modsite: NRHIDRNyEPLKtQP SwissProt Entrez-Gene
Orthologous residues
EPS8 (human): Y525‑p, EPS8 (mouse): Y524‑p, EPS8 (rat): Y525‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y576-p - FAK (human)
Modsite: RyMEDstyyKAsKGK SwissProt Entrez-Gene
Orthologous residues
FAK (human): Y576‑p, FAK iso2 (human): Y424‑p, FAK iso5 (human): Y576‑p, FAK (mouse): Y576‑p, FAK iso2 (mouse): Y607‑p, FAK iso4 (mouse): Y576‑p, FAK iso9 (mouse): , FAK (rat): Y576‑p, FAK (chicken): Y576‑p, FAK iso5 (chicken):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y411-p - Hck (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y280-p - JAM-A (human)
Modsite: tSsKkVIysQPsARs SwissProt Entrez-Gene
Orthologous residues
JAM‑A (human): Y280‑p, JAM‑A (mouse): Y281‑p, JAM‑A (rat): Y281‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y1415-p - MYH10 (human)
Modsite: LEEKALAyDKLEKTK SwissProt Entrez-Gene
Orthologous residues
MYH10 (human): Y1415‑p, MYH10 iso2 (human): Y1431‑p, MYH10 iso5 (human): Y1424‑p, MYH10 (mouse): Y1415‑p, MYH10 iso3 (mouse): Y1446‑p, MYH10 (rat): Y1415‑p, MYH10 (cow): Y1415‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y1408-p - MYH9 (human)
Modsite: HEEkVAAyDkLEkTk SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): Y1408‑p, MYH9 iso2 (human): , MYH9 (mouse): Y1408‑p, MYH9 (rat): Y1409‑p, MYH9 (cow): Y1408‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y182-p - P38D (human)
Modsite: ADAEMtGyVVtRWYR SwissProt Entrez-Gene
Orthologous residues
P38D (human): Y182‑p, P38D (mouse): Y182‑p, P38D (rat): Y182‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y301-p - PDHA1 (human)
Modsite: MsDPGVsyRtREEIQ SwissProt Entrez-Gene
Orthologous residues
PDHA1 (human): Y301‑p, PDHA1 iso2 (human): Y308‑p, PDHA1 (mouse): Y301‑p, PDHA1 (rat): Y301‑p, PDHA1 (pig): Y300‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y635-p - PEAK1 (human)
Modsite: IVINPNAyDNLAIyK SwissProt Entrez-Gene
Orthologous residues
PEAK1 (human): Y635‑p, PEAK1 (mouse): Y632‑p, PEAK1 (rat): Y631‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y452-p - PIK3R1 (human)
Modsite: VGKKLHEyNtQFQEk SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y452‑p, PIK3R1 iso2 (human): Y182‑p, PIK3R1 (mouse): Y452‑p, PIK3R1 (rat): Y452‑p, PIK3R1 (cow): Y452‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y467-p - PIK3R1 (human)
Modsite: SREyDRLyEEytRTS SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y467‑p, PIK3R1 iso2 (human): Y197‑p, PIK3R1 (mouse): Y467‑p, PIK3R1 (rat): Y467‑p, PIK3R1 (cow): Y467‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y313-p - PKCD (human)
Modsite: ssEPVGIyQGFEKKT SwissProt Entrez-Gene
Orthologous residues
PKCD (human): Y313‑p, PKCD iso2 (human): Y313‑p, PKCD (mouse): Y311‑p, PKCD iso2 (mouse): Y311‑p, PKCD (rat): Y311‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y798-p - PTPRA (human)
Modsite: yIDAFsDyANFK___ SwissProt Entrez-Gene
Orthologous residues
PTPRA (human): Y798‑p, PTPRA iso2 (human): Y789‑p, PTPRA (mouse): Y825‑p, PTPRA (rat): Y792‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y308-p - PTRF (human)
Modsite: FtPDHVVyARSktAV SwissProt Entrez-Gene
Orthologous residues
PTRF (human): Y308‑p, PTRF iso2 (human): Y218‑p, PTRF (mouse): Y310‑p, PTRF iso3 (mouse): , PTRF (rat): Y310‑p, PTRF (cow): Y308‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y118-p - PXN (human)
Modsite: VGEEEHVysFPNKQK SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN iso6 (human): Y125‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y347-p - RAIG1 (human)
Modsite: AHAWPsPykDyEVKK SwissProt Entrez-Gene
Orthologous residues
RAIG1 (human): Y347‑p, RAIG1 (mouse): Y346‑p, RAIG1 (rat): Y178‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y350-p - RAIG1 (human)
Modsite: WPsPykDyEVKKEGs SwissProt Entrez-Gene
Orthologous residues
RAIG1 (human): Y350‑p, RAIG1 (mouse): Y349‑p, RAIG1 (rat): Y181‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y986-p - SHIP-2 (human)
Modsite: NsFNNPAyyVLEGVP SwissProt Entrez-Gene
Orthologous residues
SHIP‑2 (human): Y986‑p, SHIP‑2 iso2 (human): Y744‑p, SHIP‑2 (mouse): Y987‑p, SHIP‑2 (rat): Y987‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y62-p - SHP-2 (human)
Modsite: KIQNtGDyyDLyGGE SwissProt Entrez-Gene
Orthologous residues
SHP‑2 (human): Y62‑p, SHP‑2 iso2 (human): Y62‑p, SHP‑2 (mouse): Y62‑p, SHP‑2 (rat): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLKtKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown], NCI-H358 (pulmonary) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y694-p - STAT5A (human)
Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): Y711‑p, STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y1326-p - tensin 1 (human)
Modsite: RHVAyGGystPEDRR SwissProt Entrez-Gene
Orthologous residues
tensin 1 (human): Y1326‑p, tensin 1 (mouse): Y1480‑p, tensin 1 (rat): Y1499‑p, tensin 1 (cow): Y1305‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y692-p - Vinculin (human)
Modsite: NPGNQAAyEHFEtMk SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): Y692‑p, Vinculin iso2 (human): Y692‑p, Vinculin (mouse): Y692‑p, Vinculin (rat): Y692‑p, Vinculin (chicken): Y692‑p, Vinculin (dog): Y692‑p, Vinculin (cow): Y692‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  BEAS-2B (epithelial) [LKB1 (human), knockdown]
Cellular systems studied:  cell lines
Species studied:  human
Comments:  quantitation represents log2 ratio of LKB1 knockdown vs control

Y393-p - Abl (mouse)
Modsite: RLMTGDTytAHAGAK SwissProt Entrez-Gene
Orthologous residues
Abl (human): Y393‑p, Abl iso2 (human): Y412‑p, Abl (mouse): Y393‑p, Abl iso4 (mouse): Y412‑p, Abl (rat): Y393‑p, Abl iso2 (rat): Y412‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y55-p - ACTA1 (mouse)
Modsite: GMGQkDsyVGDEAQs SwissProt Entrez-Gene
Orthologous residues
ACTA1 (human): Y55‑p, ACTA1 (mouse): Y55‑p, ACTA1 (rat): Y55‑p, ACTA1 (rabbit): Y55‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y24-p - ANXA2 (mouse)
Modsite: HStPPsAyGsVKPyt SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y24‑p, ANXA2 iso2 (human): Y42‑p, ANXA2 (mouse): Y24‑p, ANXA2 (rat): Y24‑p, ANXA2 (dog): Y24‑p, ANXA2 (cow): Y24‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y30-p - ANXA2 (mouse)
Modsite: AyGsVKPytNFDAER SwissProt Entrez-Gene
Orthologous residues
ANXA2 (human): Y30‑p, ANXA2 iso2 (human): Y48‑p, ANXA2 (mouse): Y30‑p, ANXA2 (rat): Y30‑p, ANXA2 (dog): Y30‑p, ANXA2 (cow): Y30‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y696-p - AXL (mouse)
Modsite: KKIyNGDyyRQGRIA SwissProt Entrez-Gene
Orthologous residues
AXL (human): Y702‑p, AXL iso2 (human): Y693‑p, AXL (mouse): Y696‑p, AXL (rat): Y696‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y705-p - CDCP1 (mouse)
Modsite: KGPAVGIyNGNVNTQ SwissProt Entrez-Gene
Orthologous residues
CDCP1 (human): Y707‑p, CDCP1 (mouse): Y705‑p, CDCP1 (rat): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y15-p - CDK1 (mouse)
Modsite: EKIGEGtyGVVyKGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y321-p - DYRK1A (mouse)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y380-p - DYRK2 (mouse)
Modsite: EHQRVYtyIQSRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK2 (human): Y382‑p, DYRK2 iso2 (human): Y309‑p, DYRK2 (mouse): Y380‑p, DYRK2 (rat): Y308‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y524-p - EPS8 (mouse)
Modsite: NHQVDRNyDAVKTQP SwissProt Entrez-Gene
Orthologous residues
EPS8 (human): Y525‑p, EPS8 (mouse): Y524‑p, EPS8 (rat): Y525‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y205-p - ERK1 (mouse)
Modsite: HtGFLtEyVAtRWyR SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y185-p - ERK2 (mouse)
Modsite: HtGFLtEyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y607-p - FAK iso2 (mouse)
Modsite: RyMEDstyyKAsKGK SwissProt Entrez-Gene
Orthologous residues
FAK (human): Y576‑p, FAK iso2 (human): Y424‑p, FAK iso5 (human): Y576‑p, FAK (mouse): Y576‑p, FAK iso2 (mouse): Y607‑p, FAK iso4 (mouse): Y576‑p, FAK iso9 (mouse): , FAK (rat): Y576‑p, FAK (chicken): Y576‑p, FAK iso5 (chicken):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y1105-p - GRF-1 (mouse)
Modsite: RNEEENIysVPHDST SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y409-p - Hck (mouse)
Modsite: RIIEDNEytAREGAK SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y352-p - HIPK1 (mouse)
Modsite: SKAVCStyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y281-p - JAM-A (mouse)
Modsite: APGKkVIysQPstRs SwissProt Entrez-Gene
Orthologous residues
JAM‑A (human): Y280‑p, JAM‑A (mouse): Y281‑p, JAM‑A (rat): Y281‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y1415-p - MYH10 (mouse)
Modsite: LEEKVLAyDKLEKTK SwissProt Entrez-Gene
Orthologous residues
MYH10 (human): Y1415‑p, MYH10 iso2 (human): Y1431‑p, MYH10 iso5 (human): Y1424‑p, MYH10 (mouse): Y1415‑p, MYH10 iso3 (mouse): Y1446‑p, MYH10 (rat): Y1415‑p, MYH10 (cow): Y1415‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y1408-p - MYH9 (mouse)
Modsite: LEEkVAAyDkLEkTK SwissProt Entrez-Gene
Orthologous residues
MYH9 (human): Y1408‑p, MYH9 iso2 (human): , MYH9 (mouse): Y1408‑p, MYH9 (rat): Y1409‑p, MYH9 (cow): Y1408‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y182-p - P38A (mouse)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y182-p - P38D (mouse)
Modsite: TDTEMtGyVVTRWYR SwissProt Entrez-Gene
Orthologous residues
P38D (human): Y182‑p, P38D (mouse): Y182‑p, P38D (rat): Y182‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y301-p - PDHA1 (mouse)
Modsite: MsDPGVsyRtREEIQ SwissProt Entrez-Gene
Orthologous residues
PDHA1 (human): Y301‑p, PDHA1 iso2 (human): Y308‑p, PDHA1 (mouse): Y301‑p, PDHA1 (rat): Y301‑p, PDHA1 (pig): Y300‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y632-p - PEAK1 (mouse)
Modsite: IVINPNAyDNLAIyK SwissProt Entrez-Gene
Orthologous residues
PEAK1 (human): Y635‑p, PEAK1 (mouse): Y632‑p, PEAK1 (rat): Y631‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y452-p - PIK3R1 (mouse)
Modsite: VGKKLHEyNTQFQEK SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y452‑p, PIK3R1 iso2 (human): Y182‑p, PIK3R1 (mouse): Y452‑p, PIK3R1 (rat): Y452‑p, PIK3R1 (cow): Y452‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y467-p - PIK3R1 (mouse)
Modsite: SREyDRLyEEyTRTS SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y467‑p, PIK3R1 iso2 (human): Y197‑p, PIK3R1 (mouse): Y467‑p, PIK3R1 (rat): Y467‑p, PIK3R1 (cow): Y467‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y311-p - PKCD (mouse)
Modsite: TTEsVGIyQGFEKKP SwissProt Entrez-Gene
Orthologous residues
PKCD (human): Y313‑p, PKCD iso2 (human): Y313‑p, PKCD (mouse): Y311‑p, PKCD iso2 (mouse): Y311‑p, PKCD (rat): Y311‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y849-p - PRP4 (mouse)
Modsite: ADNDItPyLVsRFYR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y825-p - PTPRA (mouse)
Modsite: YIDAFsDyANFK___ SwissProt Entrez-Gene
Orthologous residues
PTPRA (human): Y798‑p, PTPRA iso2 (human): Y789‑p, PTPRA (mouse): Y825‑p, PTPRA (rat): Y792‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y310-p - PTRF (mouse)
Modsite: FtPDHVVyARSKtAV SwissProt Entrez-Gene
Orthologous residues
PTRF (human): Y308‑p, PTRF iso2 (human): Y218‑p, PTRF (mouse): Y310‑p, PTRF iso3 (mouse): , PTRF (rat): Y310‑p, PTRF (cow): Y308‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y118-p - PXN (mouse)
Modsite: AGEEEHVysFPNKQk SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN iso6 (human): Y125‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y346-p - RAIG1 (mouse)
Modsite: AQAPAsPyNDyEGRK SwissProt Entrez-Gene
Orthologous residues
RAIG1 (human): Y347‑p, RAIG1 (mouse): Y346‑p, RAIG1 (rat): Y178‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y349-p - RAIG1 (mouse)
Modsite: PAsPyNDyEGRKGDs SwissProt Entrez-Gene
Orthologous residues
RAIG1 (human): Y350‑p, RAIG1 (mouse): Y349‑p, RAIG1 (rat): Y181‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y987-p - SHIP-2 (mouse)
Modsite: NSFNNPAyyVLEGVP SwissProt Entrez-Gene
Orthologous residues
SHIP‑2 (human): Y986‑p, SHIP‑2 iso2 (human): Y744‑p, SHIP‑2 (mouse): Y987‑p, SHIP‑2 (rat): Y987‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y62-p - SHP-2 (mouse)
Modsite: KIQNTGDyyDLyGGE SwissProt Entrez-Gene
Orthologous residues
SHP‑2 (human): Y62‑p, SHP‑2 iso2 (human): Y62‑p, SHP‑2 (mouse): Y62‑p, SHP‑2 (rat): Y62‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y424-p - Src (mouse)
Modsite: RLIEDNEytARQGAK SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y705-p - STAT3 (mouse)
Modsite: DPGsAAPyLktkFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y694-p - STAT5A (mouse)
Modsite: LAKAVDGyVKPQIKQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): Y711‑p, STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y1480-p - tensin 1 (mouse)
Modsite: RHAAyGGystPEDRR SwissProt Entrez-Gene
Orthologous residues
tensin 1 (human): Y1326‑p, tensin 1 (mouse): Y1480‑p, tensin 1 (rat): Y1499‑p, tensin 1 (cow): Y1305‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors

Y692-p - Vinculin (mouse)
Modsite: NPGNQAAyEHFEtMk SwissProt Entrez-Gene
Orthologous residues
Vinculin (human): Y692‑p, Vinculin iso2 (human): Y692‑p, Vinculin (mouse): Y692‑p, Vinculin (rat): Y692‑p, Vinculin (chicken): Y692‑p, Vinculin (dog): Y692‑p, Vinculin (cow): Y692‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  lung
Cellular systems studied:  tissue
Species studied:  mouse
Comments:  NSCLC metastases; quantitation represents log2 ratio of LKB1-deficient, KRas-activated mets vs Kras-activated primary tumors, primary NSCLC tumors; quantitation represents log2 ratio of LKB1-deficient, KRas-activated tumors vs Kras-activated tumors