Qi H, et al. (2016) Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase. J Biol Chem 291, 7742-53 26858248

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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T153-p - Tau iso8 (human) ▲

Modsite: DGKtKIAtPRGAAPP SwissProt Entrez-Gene Orthologous residues Tau (human): T470‑p, Tau iso2 (human): T95‑p, Tau iso3 (human): T59‑p, Tau iso4 (human): T124‑p, Tau iso5 (human): T153‑p, Tau iso6 (human): T95‑p, Tau iso7 (human): T124‑p, Tau iso8 (human): T153‑p, Tau (mouse): T445‑p, Tau iso3 (mouse): T142‑p, Tau iso7 (mouse): T84‑p, Tau (rat): T464‑p, Tau (cow): T144‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

T175-p - Tau iso8 (human) ▲

Modsite: AtRIPAktPPAPktP SwissProt Entrez-Gene Orthologous residues Tau (human): T492‑p, Tau iso2 (human): T117‑p, Tau iso3 (human): T81‑p, Tau iso4 (human): T146‑p, Tau iso5 (human): T175‑p, Tau iso6 (human): T117‑p, Tau iso7 (human): T146‑p, Tau iso8 (human): T175‑p, Tau (mouse): T467‑p, Tau iso3 (mouse): T164‑p, Tau iso7 (mouse): T106‑p, Tau (rat): T486‑p, Tau (cow): T166‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

T181-p - Tau iso8 (human) ▲

Modsite: ktPPAPktPPssGEP SwissProt Entrez-Gene Orthologous residues Tau (human): T498‑p, Tau iso2 (human): T123‑p, Tau iso3 (human): T87‑p, Tau iso4 (human): T152‑p, Tau iso5 (human): T181‑p, Tau iso6 (human): T123‑p, Tau iso7 (human): T152‑p, Tau iso8 (human): T181‑p, Tau (mouse): T473‑p, Tau iso3 (mouse): T170‑p, Tau iso7 (mouse): T112‑p, Tau (rat): T492‑p, Tau (cow): T172‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

S191-p - Tau iso8 (human) ▲

Modsite: ssGEPPKsGDRsGys SwissProt Entrez-Gene Orthologous residues Tau (human): S508‑p, Tau iso2 (human): S133‑p, Tau iso3 (human): S97‑p, Tau iso4 (human): S162‑p, Tau iso5 (human): S191‑p, Tau iso6 (human): S133‑p, Tau iso7 (human): S162‑p, Tau iso8 (human): S191‑p, Tau (mouse): S483‑p, Tau iso3 (mouse): S180‑p, Tau iso7 (mouse): S140‑p, Tau (rat): S502‑p, Tau (cow): S198‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

T205-p - Tau iso8 (human) ▲

Modsite: ssPGsPGtPGsRsRt SwissProt Entrez-Gene Orthologous residues Tau (human): T522‑p, Tau iso2 (human): T147‑p, Tau iso3 (human): T111‑p, Tau iso4 (human): T176‑p, Tau iso5 (human): T205‑p, Tau iso6 (human): T147‑p, Tau iso7 (human): T176‑p, Tau iso8 (human): T205‑p, Tau (mouse): T497‑p, Tau iso3 (mouse): T194‑p, Tau iso7 (mouse): T154‑p, Tau (rat): T516‑p, Tau (cow): T212‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

T231-p - Tau iso8 (human) ▲

Modsite: KKVAVVRtPPKsPss SwissProt Entrez-Gene Orthologous residues Tau (human): T548‑p, Tau iso2 (human): T173‑p, Tau iso3 (human): T137‑p, Tau iso4 (human): T202‑p, Tau iso5 (human): T231‑p, Tau iso6 (human): T173‑p, Tau iso7 (human): T202‑p, Tau iso8 (human): T231‑p, Tau (mouse): T523‑p, Tau iso3 (mouse): T220‑p, Tau iso7 (mouse): T180‑p, Tau (rat): T542‑p, Tau (cow): T238‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

S235-p - Tau iso8 (human) ▲

Modsite: VVRtPPKsPssAKsR SwissProt Entrez-Gene Orthologous residues Tau (human): S552‑p, Tau iso2 (human): S177‑p, Tau iso3 (human): S141‑p, Tau iso4 (human): S206‑p, Tau iso5 (human): S235‑p, Tau iso6 (human): S177‑p, Tau iso7 (human): S206‑p, Tau iso8 (human): S235‑p, Tau (mouse): S527‑p, Tau iso3 (mouse): S224‑p, Tau iso7 (mouse): S184‑p, Tau (rat): S546‑p, Tau (cow): S242‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

S404-p - Tau iso8 (human) ▲

Modsite: PVVsGDtsPRHLsNV SwissProt Entrez-Gene Orthologous residues Tau (human): S721‑p, Tau iso2 (human): S315‑p, Tau iso3 (human): S279‑p, Tau iso4 (human): S344‑p, Tau iso5 (human): S373‑p, Tau iso6 (human): S346‑p, Tau iso7 (human): S375‑p, Tau iso8 (human): S404‑p, Tau (mouse): S696‑p, Tau iso3 (mouse): S393‑p, Tau iso7 (mouse): S353‑p, Tau (rat): S715‑p, Tau (cow): S411‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

S422-p - Tau iso8 (human) ▲

Modsite: GsIDMVDsPQLAtLA SwissProt Entrez-Gene Orthologous residues Tau (human): S739‑p, Tau iso2 (human): S333‑p, Tau iso3 (human): S297‑p, Tau iso4 (human): S362‑p, Tau iso5 (human): S391‑p, Tau iso6 (human): S364‑p, Tau iso7 (human): S393‑p, Tau iso8 (human): S422‑p, Tau (mouse): S714‑p, Tau iso3 (mouse): S411‑p, Tau iso7 (mouse): S371‑p, Tau (rat): S733‑p, Tau (cow): S429‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)