Curated Information
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Home > Curated Information Page > PubMed Id: 29541418
Yang S, et al. (2018) Parallel comparative proteomics and phosphoproteomics reveal that cattleregulates phosphorylation of key enzymes in glycogen metabolism and glycolysis pathway. Oncotarget 9, 11352-11370 29541418
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S641-p - GYS1 (human)
Modsite: YRyPRPAsVPPsPsL SwissProt Entrez-Gene
Orthologous residues
GYS1 (human): S641‑p, GYS1 iso2 (human): S577‑p, GYS1 (mouse): S641‑p, GYS1 (rat): S641‑p, GYS1 (rabbit): S641‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  'muscle, skeletal'
Cellular systems studied:  tissue
Species studied:  cow
Comments:  Gluteal muscle
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
MSTN (human) decrease MSTN -/- increase
Downstream Regulation
Effect of modification (function):  enzymatic activity, inhibited

S645-p - GYS1 (human)
Modsite: RPAsVPPsPsLsRHs SwissProt Entrez-Gene
Orthologous residues
GYS1 (human): S645‑p, GYS1 iso2 (human): S581‑p, GYS1 (mouse): S645‑p, GYS1 (rat): S645‑p, GYS1 (rabbit): S645‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  'muscle, skeletal'
Cellular systems studied:  tissue
Species studied:  cow
Comments:  Gluteal muscle
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
MSTN (human) decrease MSTN -/- increase
Downstream Regulation
Effect of modification (function):  enzymatic activity, inhibited

S1018-p - PHKA1 (human)
Modsite: QVEFRRLsIsAESQS SwissProt Entrez-Gene
Orthologous residues
PHKA1 (human): S1018‑p, PHKA1 iso2 (human): , PHKA1 iso3 (human): , PHKA1 (mouse): S1019‑p, PHKA1 iso3 (mouse): S960‑p, PHKA1 (rat): S1020‑p, PHKA1 (rabbit): S1018‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Relevant cell lines - cell types - tissues:  'muscle, skeletal'
Cellular systems studied:  tissue
Species studied:  cow
Comments:  Gluteal muscle
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
MSTN (human) decrease MSTN -/- increase