Bohnsack JP, Carlson SL, Morrow AL (2016) Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons. Neuropharmacology 105, 124-32 26767953

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S432-p - GABRB3 (rat) ▲

Modsite: KTHLRRRssQLKIKI SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S432‑p, GABRB3 iso2 (human): S432‑p, GABRB3 (mouse): S432‑p, GABRB3 (rat): S432‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  'neuron, cortical' Cellular systems studied:  primary cells Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester no change compared to control Sp-cAMPS increase

S433-p - GABRB3 (rat) ▲

Modsite: THLRRRssQLKIKIP SwissProt Entrez-Gene Orthologous residues GABRB3 (human): S433‑p, GABRB3 iso2 (human): S433‑p, GABRB3 (mouse): S433‑p, GABRB3 (rat): S433‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  'neuron, cortical' Cellular systems studied:  primary cells Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester no change compared to control Sp-cAMPS increase

S365-p - GABRG2 (rat) ▲

Modsite: FVSNRKPsKDKDKKK SwissProt Entrez-Gene Orthologous residues GABRG2 (human): S366‑p, GABRG2 iso3 (human): S406‑p, GABRG2 (mouse): S365‑p, GABRG2 iso2 (mouse): S365‑p, GABRG2 (rat): S365‑p, GABRG2 iso2 (rat): S365‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  'neuron, cortical' Cellular systems studied:  primary cells Species studied:  rat Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase Sp-cAMPS no change compared to control phorbol_ester no change compared to control Sp-cAMPS increase