Arnold R, et al. (2005) Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1. Mol Cell Biol 25, 2364-83 15743830

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

T165-p - HPK1 (human) ▲

Modsite: ISAQIGAtLARRLsF SwissProt Entrez-Gene Orthologous residues HPK1 (human): T165‑p, HPK1 (mouse): T165‑p, HPK1 (rat): T165‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte) Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE HPK1 (human) Downstream Regulation Effect of modification (function):  enzymatic activity, induced Effect of modification (process):  transcription, altered

S171-p - HPK1 (human) ▲

Modsite: AtLARRLsFIGtPyW SwissProt Entrez-Gene Orthologous residues HPK1 (human): S171‑p, HPK1 (mouse): S171‑p, HPK1 (rat): S171‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte) Cellular systems studied:  cell lines Species studied:  human Enzymes shown to modify site in vitro:  Type Enzyme KINASE PRKD1 (human) Downstream Regulation Effect of modification (function):  enzymatic activity, induced Effect of modification (process):  transcription, altered

T175-p - HPK1 (human) ▲

Modsite: RRLsFIGtPyWMAPE SwissProt Entrez-Gene Orthologous residues HPK1 (human): T175‑p, HPK1 (mouse): T175‑p, HPK1 (rat): T175‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte) Cellular systems studied:  cell lines Species studied:  human Downstream Regulation Effect of modification (function):  enzymatic activity, induced Effect of modification (process):  transcription, altered