Curated Information
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Kang C, et al. (2012) The natively disordered loop of Bcl-2 undergoes phosphorylation-dependent conformational change and interacts with Pin1. PLoS One 7, e52047 23272207
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S87-p - Bcl-2 (human)
Modsite: AAAGPALsPVPPVVH SwissProt Entrez-Gene
Orthologous residues
Bcl‑2 (human): S87‑p, Bcl‑2 (mouse): S84‑p, Bcl‑2 (rat): S84‑p
Downstream Regulation
Effect of modification (function):  molecular association, regulation, protein conformation
Effect of modification (process):  apoptosis, inhibited
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
PIN1 (human) WW Induces NMR spectroscopy
Comments:  loop becomes less disordered