Young SA, et al. (2015) CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis. Int J Mol Sci 16, 24732-50 26501274

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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S124-p - DNAI1 (mouse) ▲

Modsite: RDEMVAGsQEsIKVV SwissProt Entrez-Gene Orthologous residues DNAI1 (human): S131‑p, DNAI1 (mouse): S124‑p, DNAI1 (rat): S124‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  mouse Comments:  CRISPR/Cas9 system to generate mutation Downstream Regulation Comments:  not essential for male fertility

S127-p - DNAI1 (mouse) ▲

Modsite: MVAGsQEsIKVVTSE SwissProt Entrez-Gene Orthologous residues DNAI1 (human): S134‑p, DNAI1 (mouse): S127‑p, DNAI1 (rat): S127‑p Characterization Methods used to characterize site in vivo:  mutation of modification site Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  mouse Comments:  CRISPR/Cas9 system to generate mutation Downstream Regulation Comments:  not essential for male fertility