Buschmann T, et al. (2000) p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation. Cancer Res 60, 896-900 10706102

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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S9-p - p53 (human) ▲

Modsite: EEPQsDPsVEPPLsQ SwissProt Entrez-Gene Orthologous residues p53 (human): S9‑p, p53 iso2 (human): S9‑p, p53 iso4 (human): ‑, p53 (mouse): S12‑p, p53 iso2 (mouse): S12‑p, p53 (rat): S9‑p, p53 (rabbit): S9‑p, p53 (green monkey): S9‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S15-p - p53 (human) ▲

Modsite: PsVEPPLsQEtFsDL SwissProt Entrez-Gene Orthologous residues p53 (human): S15‑p, p53 iso2 (human): S15‑p, p53 iso4 (human): ‑, p53 (mouse): S18‑p, p53 iso2 (mouse): S18‑p, p53 (rat): S15‑p, p53 (rabbit): S15‑p, p53 (green monkey): S15‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S20-p - p53 (human) ▲

Modsite: PLsQEtFsDLWkLLP SwissProt Entrez-Gene Orthologous residues p53 (human): S20‑p, p53 iso2 (human): S20‑p, p53 iso4 (human): ‑, p53 (mouse): S23‑p, p53 iso2 (mouse): S23‑p, p53 (rat): S20‑p, p53 (rabbit): S20‑p, p53 (green monkey): S20‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S37-p - p53 (human) ▲

Modsite: NVLsPLPsQAMDDLM SwissProt Entrez-Gene Orthologous residues p53 (human): S37‑p, p53 iso2 (human): S37‑p, p53 iso4 (human): ‑, p53 (mouse): ‑, p53 iso2 (mouse): ‑, p53 (rat): T37‑p, p53 (rabbit): S35‑p, p53 (green monkey): S37‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

K320-ac - p53 (human) ▲

Modsite: sssPQPkkkPLDGEy SwissProt Entrez-Gene Orthologous residues p53 (human): K320‑ac, p53 iso2 (human): K320‑ac, p53 iso4 (human): K281‑ac, p53 (mouse): K317‑ac, p53 iso2 (mouse): K317‑ac, p53 (rat): K318‑ac, p53 (rabbit): K318‑ac, p53 (green monkey): K320‑ac Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S371-p - p53 (human) ▲

Modsite: AHsSHLkskkGQsts SwissProt Entrez-Gene Orthologous residues p53 (human): S371‑p, p53 iso2 (human): ‑, p53 iso4 (human): S332‑p, p53 (mouse): T368‑p, p53 iso2 (mouse): ‑, p53 (rat): T369‑p, p53 (rabbit): A369‑p, p53 (green monkey): S371‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

K372-ac - p53 (human) ▲

Modsite: HsSHLkskkGQstsR SwissProt Entrez-Gene Orthologous residues p53 (human): K372‑ac, p53 iso2 (human): ‑, p53 iso4 (human): K333‑ac, p53 (mouse): K369‑ac, p53 iso2 (mouse): ‑, p53 (rat): K370‑ac, p53 (rabbit): K370‑ac, p53 (green monkey): K372‑ac Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase

S392-p - p53 (human) ▲

Modsite: FktEGPDsD______ SwissProt Entrez-Gene Orthologous residues p53 (human): S392‑p, p53 iso2 (human): ‑, p53 iso4 (human): S353‑p, p53 (mouse): S389‑p, p53 iso2 (mouse): ‑, p53 (rat): S390‑p, p53 (rabbit): S390‑p, p53 (green monkey): S392‑p Characterization Methods used to characterize site in vivo:  modification-specific antibody, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  NHF (fibroblast) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes UV increase