Curated Information
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Home > Curated Information Page > PubMed Id: 26271711
Brunet S, et al. (2015) Phosphorylation sites in the Hook domain of CaVĪ² subunits differentially modulate CaV1.2 channel function. J Mol Cell Cardiol 87, 248-56 26271711
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S152-p - CACNB2 iso2 (human)
Modsite: SGGNSSSsLGDIVPS SwissProt Entrez-Gene
Orthologous residues
CACNB2 (human): S207‑p, CACNB2 iso2 (human): S152‑p, CACNB2 iso3 (human): S153‑p, CACNB2 iso6 (human): S152‑p, CACNB2 iso8 (human): S207‑p, CACNB2 (mouse): S203‑p, CACNB2 (rat): S203‑p, CACNB2 iso2 (rat): S152‑p, CACNB2 (rabbit): S179‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  tsA201 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

T164-p - CACNB2 iso2 (human)
Modsite: VPSSRKStPPSSAID SwissProt Entrez-Gene
Orthologous residues
CACNB2 (human): T219‑p, CACNB2 iso2 (human): T164‑p, CACNB2 iso3 (human): T165‑p, CACNB2 iso6 (human): T164‑p, CACNB2 iso8 (human): T219‑p, CACNB2 (mouse): T215‑p, CACNB2 (rat): T215‑p, CACNB2 iso2 (rat): T164‑p, CACNB2 (rabbit): T191‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  tsA201 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human

S193-p - CACNB1 (rabbit)
Modsite: SGDNSSSsLGDVVTG SwissProt
Orthologous residues
CACNB1 (human): S193‑p, CACNB1 iso2 (human): S193‑p, CACNB1 (mouse): S193‑p, CACNB1 iso2 (mouse): S193‑p, CACNB1 iso5 (mouse): S146‑p, CACNB1 (rat): S193‑p, CACNB1 (rabbit): S193‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mass spectrometry (in vitro)
Relevant cell lines - cell types - tissues:  'muscle, skeletal'
Cellular systems studied:  tissue
Species studied:  rabbit

T205-p - CACNB1 (rabbit)
Modsite: VTGTRRPtPPASGNE SwissProt
Orthologous residues
CACNB1 (human): T205‑p, CACNB1 iso2 (human): T205‑p, CACNB1 (mouse): T205‑p, CACNB1 iso2 (mouse): T205‑p, CACNB1 iso5 (mouse): T158‑p, CACNB1 (rat): T205‑p, CACNB1 (rabbit): T205‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mass spectrometry (in vitro)
Relevant cell lines - cell types - tissues:  'muscle, skeletal'
Cellular systems studied:  tissue
Species studied:  rabbit
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)