Solan JL, Fry MD, TenBroek EM, Lampe PD (2003) Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation. J Cell Sci 116, 2203-11 12697837

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S369-p - GJA1 (rat) ▲

Modsite: RPssRAssRAssRPR SwissProt Entrez-Gene Orthologous residues GJA1 (human): S369‑p, GJA1 (mouse): S369‑p, GJA1 (rat): S369‑p, GJA1 (rabbit): S369‑p, GJA1 (pig): S369‑p, GJA1 (hamster): S369‑p, GJA1 (cow): S370‑p Characterization Methods used to characterize site in vivo:  immunoprecipitation, microscopy-colocalization with upstream kinase, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  CHO (fibroblast), HeLa (cervical), NRK (fibroblast) Cellular systems studied:  cell lines Species studied:  rat Upstream Regulation Potential in vivo enzymes for site:  Type Enzyme Evidence Notes KINASE PKCA (rat) modification site within consensus motif, phospho-motif antibody, pharmacological activator of upstream enzyme Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase Downstream Regulation Effect of modification (function):  intracellular localization Comments:  altered intracellular localization during cell cycle