Curated Information
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Home > Curated Information Page > PubMed Id: 18438403
Rathert P, et al. (2008) Protein lysine methyltransferase G9a acts on non-histone targets. Nat Chem Biol 4, 344-6 18438403
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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K654-m2 - acinus (human)
Modsite: SASSNSRksLsPGVs SwissProt Entrez-Gene
Orthologous residues
acinus (human): K654‑m2, acinus iso2 (human): , acinus iso5 (human): K654‑m2, acinus (mouse): K654‑m2, acinus iso4 (mouse): K614‑m2, acinus iso5 (mouse): , acinus (rat): K655‑m2, acinus (cow): K648‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K135-m1 - CDYL (human)
Modsite: tsPNNARkQISRSTN SwissProt Entrez-Gene
Orthologous residues
CDYL (human): K135‑m1, CDYL iso2 (human): K81‑m1, CDYL (mouse): K130‑m1, CDYL (rat): K129‑m1
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K135-m2 - CDYL (human)
Modsite: tsPNNARkQISRSTN SwissProt Entrez-Gene
Orthologous residues
CDYL (human): K135‑m2, CDYL iso2 (human): K81‑m2, CDYL (mouse): K130‑m2, CDYL (rat): K129‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K135-m3 - CDYL (human)
Modsite: tsPNNARkQISRSTN SwissProt Entrez-Gene
Orthologous residues
CDYL (human): K135‑m3, CDYL iso2 (human): K81‑m3, CDYL (mouse): K130‑m3, CDYL (rat): K129‑m3
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K70-m2 - DNMT1 (human)
Modsite: DLETkLRkEELSEEG SwissProt Entrez-Gene
Orthologous residues
DNMT1 (human): K70‑m2, DNMT1 iso2 (human): K70‑m2, DNMT1 (mouse): K70‑m2, DNMT1 (rat): K70‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K242-m2 - EHMT2 iso4 (human)
Modsite: PKVHRARkTMSkPGN SwissProt Entrez-Gene
Orthologous residues
EHMT2 (human): K185‑m2, EHMT2 iso2 (human): K185‑m2, EHMT2 iso4 (human): K242‑m2, EHMT2 (mouse): K239‑m2, EHMT2 iso4 (mouse): , EHMT2 (rat): K239‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K242-m3 - EHMT2 iso4 (human)
Modsite: PKVHRARkTMSkPGN SwissProt Entrez-Gene
Orthologous residues
EHMT2 (human): K185‑m3, EHMT2 iso2 (human): K185‑m3, EHMT2 iso4 (human): K242‑m3, EHMT2 (mouse): K239‑m3, EHMT2 iso4 (mouse): , EHMT2 (rat): K239‑m3
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K170-me - ERCC6 (human)
Modsite: TSRDINRkLDsVKRQ SwissProt Entrez-Gene
Orthologous residues
ERCC6 (human): K170‑me, ERCC6 (mouse): K170‑me, ERCC6 (rat): K170‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K297-me - ERCC6 (human)
Modsite: CNKRAARkAPAPVtP SwissProt Entrez-Gene
Orthologous residues
ERCC6 (human): K297‑me, ERCC6 (mouse): K298‑me, ERCC6 (rat): K298‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K448-me - ERCC6 (human)
Modsite: EGGGGGRkVGRYRDD SwissProt Entrez-Gene
Orthologous residues
ERCC6 (human): K448‑me, ERCC6 (mouse): K444‑me, ERCC6 (rat): K421‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K1054-me - ERCC6 (human)
Modsite: DHDVPKRkKFPASNI SwissProt Entrez-Gene
Orthologous residues
ERCC6 (human): K1054‑me, ERCC6 (mouse): K1047‑me, ERCC6 (rat): K955‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K26-me - H1E (human)
Modsite: PVkKKARksAGAAkR SwissProt Entrez-Gene
Orthologous residues
H1E (human): K26‑me, H1E (mouse): K26‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

R8-m2 - H3 (human)
Modsite: ArtkQtArkstGGkA SwissProt Entrez-Gene
Orthologous residues
H3 (human): R8‑m2, H3 (mouse): R8‑m2, H3 iso2 (mouse): R8‑m2, H3 iso3 (mouse): R8‑m2, H3 (rat): R8‑m2, H3 iso3 (rat): R8‑m2, H3 (pig): R8‑m2, H3 (chicken): R8‑m2, H3 (cow): R8‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K9-m2 - H3 (human)
Modsite: rtkQtArkstGGkAP SwissProt Entrez-Gene
Orthologous residues
H3 (human): K9‑m2, H3 (mouse): K9‑m2, H3 iso2 (mouse): K9‑m2, H3 iso3 (mouse): K9‑m2, H3 (rat): K9‑m2, H3 iso3 (rat): K9‑m2, H3 (pig): K9‑m2, H3 (chicken): K9‑m2, H3 (cow): K9‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K9-m3 - H3 (human)
Modsite: rtkQtArkstGGkAP SwissProt Entrez-Gene
Orthologous residues
H3 (human): K9‑m3, H3 (mouse): K9‑m3, H3 iso2 (mouse): K9‑m3, H3 iso3 (mouse): K9‑m3, H3 (rat): K9‑m3, H3 iso3 (rat): K9‑m3, H3 (pig): K9‑m3, H3 (chicken): K9‑m3, H3 (cow): K9‑m3
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

S10-p - H3 (human)
Modsite: tkQtArkstGGkAPr SwissProt Entrez-Gene
Orthologous residues
H3 (human): S10‑p, H3 (mouse): S10‑p, H3 iso2 (mouse): S10‑p, H3 iso3 (mouse): S10‑p, H3 (rat): S10‑p, H3 iso3 (rat): S10‑p, H3 (pig): S10‑p, H3 (chicken): S10‑p, H3 (cow): S10‑p
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K27-me - H3 (human)
Modsite: LATkAArksAPATGG SwissProt Entrez-Gene
Orthologous residues
H3 (human): K27‑me, H3 (mouse): K27‑me, H3 iso2 (mouse): K27‑me, H3 iso3 (mouse): K27‑me, H3 (rat): K27‑me, H3 iso3 (rat): K27‑me, H3 (pig): K27‑me, H3 (chicken): K27‑me, H3 (cow): K27‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K432-me - HDAC1 (human)
Modsite: EEGEGGRkNssNFkk SwissProt Entrez-Gene
Orthologous residues
HDAC1 (human): K432‑me, HDAC1 (mouse): K432‑me, HDAC1 (rat): K432‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K313-me - KLF12 (human)
Modsite: SEsPDSRkRRIHRCD SwissProt Entrez-Gene
Orthologous residues
KLF12 (human): K313‑me, KLF12 (mouse): K313‑me, KLF12 (rat): K320‑me
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K1162-m2 - WIZ (human)
Modsite: sPPPtARkMFPGLAA SwissProt Entrez-Gene
Orthologous residues
WIZ (human): K1162‑m2, WIZ iso2 (human): K305‑m2, WIZ iso3 (human): K476‑m2, WIZ (mouse): K1195‑m2, WIZ (rat): K473‑m2
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)

K1162-m3 - WIZ (human)
Modsite: sPPPtARkMFPGLAA SwissProt Entrez-Gene
Orthologous residues
WIZ (human): K1162‑m3, WIZ iso2 (human): K305‑m3, WIZ iso3 (human): K476‑m3, WIZ (mouse): K1195‑m3, WIZ (rat): K473‑m3
Characterization
Methods used to characterize site in vivo mass spectrometry (in vitro)
Enzymes shown to modify site in vitro
Type Enzyme
METHYLTRANSFERASE EHMT2 (human)