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Home > Curated Information Page > Cst Curation Set #18856
Rikova K (2013) CST Curation Set: 18856; Year: 2013; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](PSD)
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
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S668-p - AFAP (human)
Modsite: sGtssPQsPVFRHRt SwissProt Entrez-Gene
Orthologous residues
AFAP (human): S668‑p, AFAP iso2 (human): S752‑p, AFAP (mouse): S669‑p, AFAP (rat): S669‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S187-p - AKAP10 (human)
Modsite: SSLAEPVsPsKKHET SwissProt Entrez-Gene
Orthologous residues
AKAP10 (human): S187‑p, AKAP10 (mouse): S187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S311-p - APLP2 (human)
Modsite: HDVKAVCsQEAMtGP SwissProt Entrez-Gene
Orthologous residues
APLP2 (human): S311‑p, APLP2 iso2 (human): , APLP2 iso3 (human): S311‑p, APLP2 iso5 (human): , APLP2 (mouse): , APLP2 iso3 (mouse): S311‑p, APLP2 (rat): S313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T316-p - APLP2 (human)
Modsite: VCsQEAMtGPCRAVM SwissProt Entrez-Gene
Orthologous residues
APLP2 (human): T316‑p, APLP2 iso2 (human): , APLP2 iso3 (human): T316‑p, APLP2 iso5 (human): , APLP2 (mouse): , APLP2 iso3 (mouse): T316‑p, APLP2 (rat): T318‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1029-p - ARHGAP29 (human)
Modsite: VDRLLLAsPPNERNG SwissProt Entrez-Gene
Orthologous residues
ARHGAP29 (human): S1029‑p, ARHGAP29 (mouse): S1039‑p, ARHGAP29 (rat): G1034‑p, ARHGAP29 (cow): S1037‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1609-p - ARID1A (human)
Modsite: sKsPFLHsGMkMQKA SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): S1609‑p, ARID1A iso2 (human): S1392‑p, ARID1A (mouse): S1610‑p, ARID1A (rat): S1617‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S669-p - ataxin-2 (human)
Modsite: PVArtsPsGGtWsSV SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): S669‑p, ataxin‑2 iso2 (human): S669‑p, ataxin‑2 (mouse): A638‑p, ataxin‑2 iso2 (mouse): A568‑p, ataxin‑2 (rat): A201‑p, ataxin‑2 (cow): A651‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T672-p - ataxin-2 (human)
Modsite: rtsPsGGtWsSVVsG SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): T672‑p, ataxin‑2 iso2 (human): T672‑p, ataxin‑2 (mouse): T641‑p, ataxin‑2 iso2 (mouse): T571‑p, ataxin‑2 (rat): T204‑p, ataxin‑2 (cow): T654‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S674-p - ataxin-2 (human)
Modsite: sPsGGtWsSVVsGVP SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): S674‑p, ataxin‑2 iso2 (human): S674‑p, ataxin‑2 (mouse): S643‑p, ataxin‑2 iso2 (mouse): S573‑p, ataxin‑2 (rat): S206‑p, ataxin‑2 (cow): S656‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S255-p - ATG2B (human)
Modsite: VEtEPKLsPsWNPKI SwissProt Entrez-Gene
Orthologous residues
ATG2B (human): S255‑p, ATG2B iso100 (human): S255‑p, ATG2B (mouse): S255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S310-p - CAF-1A (human)
Modsite: PKQHSstsPFPtstP SwissProt Entrez-Gene
Orthologous residues
CAF‑1A (human): S310‑p, CAF‑1A iso2 (human): S310‑p, CAF‑1A iso100 (human): S310‑p, CAF‑1A (mouse): S293‑p, CAF‑1A (rat): S293‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T848-p - CASKIN2 (human)
Modsite: tsPSVtPtPArGtPR SwissProt Entrez-Gene
Orthologous residues
CASKIN2 (human): T848‑p, CASKIN2 iso2 (human): T766‑p, CASKIN2 (mouse): T847‑p, CASKIN2 (rat): T847‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S494-p - CCDC132 (human)
Modsite: KFMEQsRsPsVsPsk SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S494‑p, CCDC132 iso3 (human): S464‑p, CCDC132 (mouse): S494‑p, CCDC132 (rat): S54‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S496-p - CCDC132 (human)
Modsite: MEQsRsPsVsPskQP SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S496‑p, CCDC132 iso3 (human): S466‑p, CCDC132 (mouse): S496‑p, CCDC132 (rat): S56‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S498-p - CCDC132 (human)
Modsite: QsRsPsVsPskQPVs SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S498‑p, CCDC132 iso3 (human): S468‑p, CCDC132 (mouse): S498‑p, CCDC132 (rat): S58‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

Y115-p - CDC23 (human)
Modsite: GCNSkKAyFLYMysR SwissProt Entrez-Gene
Orthologous residues
CDC23 (human): Y115‑p, CDC23 (mouse): Y115‑p, CDC23 (rat): Y115‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2046-p - CHD-8 (human)
Modsite: QDyEMrVsPsDttPL SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): S2046‑p, CHD‑8 iso2 (human): S1767‑p, CHD‑8 (mouse): G2048‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): A2046‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2048-p - CHD-8 (human)
Modsite: yEMrVsPsDttPLVs SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): S2048‑p, CHD‑8 iso2 (human): S1769‑p, CHD‑8 (mouse): S2050‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): S2048‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T2050-p - CHD-8 (human)
Modsite: MrVsPsDttPLVsRS SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): T2050‑p, CHD‑8 iso2 (human): T1771‑p, CHD‑8 (mouse): T2052‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): T2050‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S121-p - EHMT2 (human)
Modsite: ksFPssPskGGSCPS SwissProt Entrez-Gene
Orthologous residues
EHMT2 (human): S121‑p, EHMT2 iso2 (human): S121‑p, EHMT2 iso4 (human): S178‑p, EHMT2 (mouse): S174‑p, EHMT2 iso4 (mouse): , EHMT2 (rat): S174‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1900-p - ELYS (human)
Modsite: VSTVTsPsRMIRKLR SwissProt Entrez-Gene
Orthologous residues
ELYS (human): S1900‑p, ELYS iso2 (human): S1935‑p, ELYS (mouse): D1886‑p, ELYS (rat): G1884‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T396-p - FAM117B (human)
Modsite: tRsIDTQtPGGADRG SwissProt Entrez-Gene
Orthologous residues
FAM117B (human): T396‑p, FAM117B (mouse): T391‑p, FAM117B (rat): T152‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S138-p - FETUA (human)
Modsite: kCDssPDsAEDVrkV SwissProt Entrez-Gene
Orthologous residues
FETUA (human): S138‑p, FETUA (mouse): S138‑p, FETUA (rat): S138‑p, FETUA (cow): S138‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T1020-p - FMNL1 (human)
Modsite: AQEAGADtPGKGEPP SwissProt Entrez-Gene
Orthologous residues
FMNL1 (human): T1020‑p, FMNL1 iso2 (human): T1020‑p, FMNL1 (mouse): T1010‑p, FMNL1 iso2 (mouse): T984‑p, FMNL1 (rat): T954‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1031-p - FMNL1 (human)
Modsite: GEPPAPKsPPKARRP SwissProt Entrez-Gene
Orthologous residues
FMNL1 (human): S1031‑p, FMNL1 iso2 (human): S1031‑p, FMNL1 (mouse): S1021‑p, FMNL1 iso2 (mouse): S995‑p, FMNL1 (rat): S965‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T229-p - GANAB (human)
Modsite: EPGAWEEtFkTHSDS SwissProt Entrez-Gene
Orthologous residues
GANAB (human): T229‑p, GANAB iso2 (human): T251‑p, GANAB (mouse): T229‑p, GANAB iso2 (mouse): T251‑p, GANAB (rat): T82‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T16-p - GNPAT (human)
Modsite: SYFSVGPtsPSAVVL SwissProt Entrez-Gene
Orthologous residues
GNPAT (human): T16‑p, GNPAT (mouse): A16‑p, GNPAT (rat): A16‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S243-p - GTSE1 (human)
Modsite: PKKEIPAsPsRTKIP SwissProt Entrez-Gene
Orthologous residues
GTSE1 (human): S243‑p, GTSE1 (mouse): S245‑p, GTSE1 (rat): S254‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S245-p - GTSE1 (human)
Modsite: KEIPAsPsRTKIPAE SwissProt Entrez-Gene
Orthologous residues
GTSE1 (human): S245‑p, GTSE1 (mouse): Q247‑p, GTSE1 (rat): Q256‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S424-p - HDAC3 (human)
Modsite: DHDNDKEsDVEI___ SwissProt Entrez-Gene
Orthologous residues
HDAC3 (human): S424‑p, HDAC3 iso2 (human): S425‑p, HDAC3 (mouse): S424‑p, HDAC3 (rat): S424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1108-p - HDAC5 (human)
Modsite: AAAAREHsPRPAEEP SwissProt Entrez-Gene
Orthologous residues
HDAC5 (human): S1108‑p, HDAC5 iso2 (human): S1023‑p, HDAC5 iso3 (human): S1109‑p, HDAC5 (mouse): S1099‑p, HDAC5 (rat): S932‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S155-p - HDAC7 (human)
Modsite: FPLRKtVsEPNLkLR SwissProt Entrez-Gene
Orthologous residues
HDAC7 (human): S155‑p, HDAC7 iso3 (human): S155‑p, HDAC7 iso5 (human): S194‑p, HDAC7 iso7 (human): S194‑p, HDAC7 iso8 (human): S211‑p, HDAC7 (mouse): S178‑p, HDAC7 (rat): S156‑p, HDAC7 (cow): S196‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T2701-p - HERC1 (human)
Modsite: LPTRRAQtPPIssLP SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): T2701‑p, HERC1 (mouse): T2699‑p, HERC1 (rat): T2699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2705-p - HERC1 (human)
Modsite: RAQtPPIssLPtsPS SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2705‑p, HERC1 (mouse): S2703‑p, HERC1 (rat): S2703‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2706-p - HERC1 (human)
Modsite: AQtPPIssLPtsPSD SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2706‑p, HERC1 (mouse): S2704‑p, HERC1 (rat): S2704‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1047-p - IARS (human)
Modsite: PLkPyPVsPsDkVLI SwissProt Entrez-Gene
Orthologous residues
IARS (human): S1047‑p, IARS (mouse): P1047‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T435-p - IFI16 (human)
Modsite: tPQMPPttPssSFFT SwissProt Entrez-Gene
Orthologous residues
IFI16 (human): T435‑p, IFI16 iso2 (human): T435‑p, IFI16 iso3 (human): T435‑p, IFI16 (mouse): , IFI16 iso6 (mouse):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S600-p - INT4 (human)
Modsite: KLVSSAVsPSIIPQE SwissProt Entrez-Gene
Orthologous residues
INT4 (human): S600‑p, INT4 iso2 (human): , INT4 iso3 (human): S452‑p, INT4 (mouse): P601‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S348-p - IRS1 (human)
Modsite: sVDGsPVsPstNRTH SwissProt Entrez-Gene
Orthologous residues
IRS1 (human): S348‑p, IRS1 (mouse): S343‑p, IRS1 (rat): S343‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1162-p - IRS2 (human)
Modsite: TttVtPVsPsFAHNP SwissProt Entrez-Gene
Orthologous residues
IRS2 (human): S1162‑p, IRS2 (mouse): S1151‑p, IRS2 (rat): S1154‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S971-p - KIAA1522 (human)
Modsite: PPVARKPsVGVPPPA SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S971‑p, KIAA1522 iso2 (human): S1030‑p, KIAA1522 (mouse): S952‑p, KIAA1522 iso2 (mouse): S1009‑p, KIAA1522 (rat): S956‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S979-p - KIAA1522 (human)
Modsite: VGVPPPAsPsyPRAE SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S979‑p, KIAA1522 iso2 (human): S1038‑p, KIAA1522 (mouse): S959‑p, KIAA1522 iso2 (mouse): S1016‑p, KIAA1522 (rat): S962‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S933-p - KIF5B (human)
Modsite: PGQHPAAsPtHPsAI SwissProt Entrez-Gene
Orthologous residues
KIF5B (human): S933‑p, KIF5B (mouse): S933‑p, KIF5B (rat): S933‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S608-p - L3MBTL3 (human)
Modsite: sGEMPPAsPsFPRNK SwissProt Entrez-Gene
Orthologous residues
L3MBTL3 (human): S608‑p, L3MBTL3 iso2 (human): S583‑p, L3MBTL3 (mouse): T609‑p, L3MBTL3 (rat): S607‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S222-p - MAVS (human)
Modsite: tPSRGPVsPsVSFQP SwissProt Entrez-Gene
Orthologous residues
MAVS (human): S222‑p, MAVS iso4 (human): S81‑p, MAVS (mouse): S220‑p, MAVS (rat): S220‑p, MAVS (cow): S221‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S154-p - MCMBP (human)
Modsite: NANQARVsPStsytP SwissProt Entrez-Gene
Orthologous residues
MCMBP (human): S154‑p, MCMBP iso2 (human): S154‑p, MCMBP (mouse): S154‑p, MCMBP (rat): S154‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S444-p - MEF2D (human)
Modsite: SIkSEPVsPsRERsP SwissProt Entrez-Gene
Orthologous residues
MEF2D (human): S444‑p, MEF2D iso2 (human): S443‑p, MEF2D iso4 (human): S437‑p, MEF2D (mouse): S437‑p, MEF2D iso2 (mouse): S437‑p, MEF2D (rat): S430‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S446-p - MEF2D (human)
Modsite: kSEPVsPsRERsPAP SwissProt Entrez-Gene
Orthologous residues
MEF2D (human): S446‑p, MEF2D iso2 (human): S445‑p, MEF2D iso4 (human): S439‑p, MEF2D (mouse): S439‑p, MEF2D iso2 (mouse): S439‑p, MEF2D (rat): S432‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S326-p - MIG-6 (human)
Modsite: VPPREPLsPSNsRTP SwissProt Entrez-Gene
Orthologous residues
MIG‑6 (human): S326‑p, MIG‑6 (mouse): S325‑p, MIG‑6 (rat): S324‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2296-p - MLL4 (human)
Modsite: KEELGAssPsyGPPN SwissProt Entrez-Gene
Orthologous residues
MLL4 (human): S2296‑p, MLL4 iso3 (human): S2299‑p, MLL4 (mouse): S2253‑p, MLL4 (rat): S2245‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S593-p - MTM1 (human)
Modsite: PtsPssPsQMMPHVQ SwissProt Entrez-Gene
Orthologous residues
MTM1 (human): S593‑p, MTM1 (mouse): S593‑p, MTM1 (rat): A592‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T260-p - MTSS1L (human)
Modsite: DYSWsyQtPPssPsS SwissProt Entrez-Gene
Orthologous residues
MTSS1L (human): T260‑p, MTSS1L (mouse): T257‑p, MTSS1L (rat): T260‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S701-p - NAV1 (human)
Modsite: VSSsIDPsLLSTkQG SwissProt Entrez-Gene
Orthologous residues
NAV1 (human): S701‑p, NAV1 iso2 (human): S701‑p, NAV1 iso5 (human): S310‑p, NAV1 (mouse): S703‑p, NAV1 (rat): S703‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S473-p - NFI-C (human)
Modsite: GGATSPtsPsysPPD SwissProt Entrez-Gene
Orthologous residues
NFI‑C (human): S473‑p, NFI‑C iso2 (human): S464‑p, NFI‑C (mouse): , NFI‑C (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T903-p - NUP188 (human)
Modsite: AIRDAFLtRLQskIE SwissProt Entrez-Gene
Orthologous residues
NUP188 (human): T903‑p, NUP188 iso2 (human): T792‑p, NUP188 (mouse): T903‑p, NUP188 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S907-p - NUP188 (human)
Modsite: AFLtRLQskIEDMRI SwissProt Entrez-Gene
Orthologous residues
NUP188 (human): S907‑p, NUP188 iso2 (human): S796‑p, NUP188 (mouse): S907‑p, NUP188 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1796-p - PHF3 (human)
Modsite: PrTSTNFsPMrPQQP SwissProt Entrez-Gene
Orthologous residues
PHF3 (human): S1796‑p, PHF3 iso2 (human): S1708‑p, PHF3 (mouse): S1780‑p, PHF3 (rat): S1777‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S461-p - PHLDB1 (human)
Modsite: MRELPPLsPsLsRRA SwissProt Entrez-Gene
Orthologous residues
PHLDB1 (human): S461‑p, PHLDB1 iso2 (human): S461‑p, PHLDB1 (mouse): S463‑p, PHLDB1 (rat): S462‑p, PHLDB1 (cow): S463‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T1842-p - POLR2A (human)
Modsite: AsPKytPtsPsysPs SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): T1842‑p, POLR2A iso100 (human): T1842‑p, POLR2A (mouse): T1842‑p, POLR2A (rat): T1842‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1843-p - POLR2A (human)
Modsite: sPKytPtsPsysPss SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): S1843‑p, POLR2A iso100 (human): S1843‑p, POLR2A (mouse): S1843‑p, POLR2A (rat): S1843‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1845-p - POLR2A (human)
Modsite: KytPtsPsysPssPE SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): S1845‑p, POLR2A iso100 (human): S1845‑p, POLR2A (mouse): S1845‑p, POLR2A (rat): S1845‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T1856-p - POLR2A (human)
Modsite: ssPEytPtsPKysPt SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): T1856‑p, POLR2A iso100 (human): T1856‑p, POLR2A (mouse): A1856‑p, POLR2A (rat): T1856‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T714-p - PPFIA3 (human)
Modsite: GPAIPGDtPPPtPRs SwissProt Entrez-Gene
Orthologous residues
PPFIA3 (human): T714‑p, PPFIA3 iso2 (human): T714‑p, PPFIA3 (mouse): T714‑p, PPFIA3 (rat): T712‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T210-p - PYGB (human)
Modsite: FyGRVEHtPDGVKWL SwissProt Entrez-Gene
Orthologous residues
PYGB (human): T210‑p, PYGB (mouse): T210‑p, PYGB (rat): T210‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1103-p - RAP140 (human)
Modsite: GGNLPPVsPNDsGAK SwissProt Entrez-Gene
Orthologous residues
RAP140 (human): S1103‑p, RAP140 iso2 (human): S666‑p, RAP140 iso3 (human): S1103‑p, RAP140 (mouse): S1059‑p, RAP140 iso2 (mouse): S1089‑p, RAP140 (rat): S1097‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S841-p - RASAL2 (human)
Modsite: FTKRsTQsEDFSRRH SwissProt Entrez-Gene
Orthologous residues
RASAL2 (human): S841‑p, RASAL2 iso2 (human): S982‑p, RASAL2 (mouse): S988‑p, RASAL2 (rat): S639‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1695-p - RBBP6 (human)
Modsite: SRNQsHssPsVsPsR SwissProt Entrez-Gene
Orthologous residues
RBBP6 (human): S1695‑p, RBBP6 iso2 (human): S1661‑p, RBBP6 (mouse): S1695‑p, RBBP6 iso2 (mouse): S1661‑p, RBBP6 (rat): S1694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1066-p - SETDB1 (human)
Modsite: RNYGYNPsPVkPEGL SwissProt Entrez-Gene
Orthologous residues
SETDB1 (human): S1066‑p, SETDB1 iso3 (human): S1066‑p, SETDB1 (mouse): , SETDB1 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S338-p - SIRT6 (human)
Modsite: PKRERPtsPAPHRPP SwissProt Entrez-Gene
Orthologous residues
SIRT6 (human): S338‑p, SIRT6 iso2 (human): S311‑p, SIRT6 (mouse): S317‑p, SIRT6 (rat): S313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S391-p - SUV39H1 (human)
Modsite: GLAGLPGsPKKRVRI SwissProt Entrez-Gene
Orthologous residues
SUV39H1 (human): S391‑p, SUV39H1 (mouse): S391‑p, SUV39H1 (rat): S392‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1053-p - SYNJ1 (human)
Modsite: PRtsPCQsPTIsEGP SwissProt Entrez-Gene
Orthologous residues
SYNJ1 (human): S1053‑p, SYNJ1 iso2 (human): S1053‑p, SYNJ1 iso3 (human): S1053‑p, SYNJ1 (mouse): S1053‑p, SYNJ1 iso3 (mouse): S1093‑p, SYNJ1 iso6 (mouse): , SYNJ1 (rat): S1053‑p, SYNJ1 iso4 (rat): S1053‑p, SYNJ1 iso5 (rat): S1053‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T86-p - TAX1BP3 (human)
Modsite: QVNGWDMtMVTHDQA SwissProt Entrez-Gene
Orthologous residues
TAX1BP3 (human): T86‑p, TAX1BP3 (mouse): T86‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S386-p - TCF12 (human)
Modsite: PGGQAPssPsYENsL SwissProt Entrez-Gene
Orthologous residues
TCF12 (human): S386‑p, TCF12 iso2 (human): S216‑p, TCF12 iso3 (human): S386‑p, TCF12 iso4 (human): S150‑p, TCF12 (mouse): S386‑p, TCF12 iso2 (mouse): S386‑p, TCF12 (rat): S387‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S203-p - TERF2IP (human)
Modsite: LLGDAPVsPssQkLK SwissProt Entrez-Gene
Orthologous residues
TERF2IP (human): S203‑p, TERF2IP (mouse): S200‑p, TERF2IP (rat): S200‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T46-p - VGLL4 (human)
Modsite: SALSSHRtGPPPIsP SwissProt Entrez-Gene
Orthologous residues
VGLL4 (human): T46‑p, VGLL4 iso2 (human): T15‑p, VGLL4 iso4 (human): T52‑p, VGLL4 (mouse): T52‑p, VGLL4 (rat): T52‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S52-p - VGLL4 (human)
Modsite: RtGPPPIsPsKRKFs SwissProt Entrez-Gene
Orthologous residues
VGLL4 (human): S52‑p, VGLL4 iso2 (human): S21‑p, VGLL4 iso4 (human): S58‑p, VGLL4 (mouse): S58‑p, VGLL4 (rat): S58‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T212-p - WIRE (human)
Modsite: REKPLPPtPGQRLHP SwissProt Entrez-Gene
Orthologous residues
WIRE (human): T212‑p, WIRE iso2 (human): T62‑p, WIRE (mouse): T212‑p, WIRE (rat): T212‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S620-p - ZC3H14 (human)
Modsite: CAYHHPIsPCkAFPN SwissProt Entrez-Gene
Orthologous residues
ZC3H14 (human): S620‑p, ZC3H14 iso2 (human): S620‑p, ZC3H14 iso3 (human): S464‑p, ZC3H14 iso4 (human): S455‑p, ZC3H14 iso5 (human): S595‑p, ZC3H14 iso6 (human): S191‑p, ZC3H14 iso9 (human): S615‑p, ZC3H14 (mouse): S620‑p, ZC3H14 (rat): S620‑p, ZC3H14 (cow): S620‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1617-p - ZO1 (human)
Modsite: VPKAIPVsPsAVEED SwissProt Entrez-Gene
Orthologous residues
ZO1 (human): S1617‑p, ZO1 iso2 (human): S1537‑p, ZO1 (mouse): S1614‑p, ZO1 iso2 (mouse): S1534‑p, ZO1 (rat): S1602‑p, ZO1 (cow): S1581‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer, non-small cell lung adenocarcinoma
Relevant cell lines - cell types - tissues:  NCI-H2228 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved