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Home > Curated Information Page > Cst Curation Set #18857
Rikova K (2013) CST Curation Set: 18857; Year: 2013; Biosample/Treatment: cell line, H3122/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](PSD)
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
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S668-p - AFAP (human)
Modsite: sGtssPQsPVFRHRt SwissProt Entrez-Gene
Orthologous residues
AFAP (human): S668‑p, AFAP iso2 (human): S752‑p, AFAP (mouse): S669‑p, AFAP (rat): S669‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S187-p - AKAP10 (human)
Modsite: SSLAEPVsPsKKHET SwissProt Entrez-Gene
Orthologous residues
AKAP10 (human): S187‑p, AKAP10 (mouse): S187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S152-p - AKAP2 (human)
Modsite: DsLQVPVsPssTtss SwissProt Entrez-Gene
Orthologous residues
AKAP2 (human): S152‑p, AKAP2 iso4 (human): S383‑p, AKAP2 iso6 (human): S383‑p, AKAP2 (mouse): S152‑p, AKAP2 iso2 (mouse): S152‑p, AKAP2 iso3 (mouse): S152‑p, AKAP2 iso6 (mouse): S193‑p, AKAP2 (rat): S152‑p, AKAP2 (cow): S152‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S301-p - ArgBP2 (human)
Modsite: sFTsssPssPsRAKG SwissProt Entrez-Gene
Orthologous residues
ArgBP2 (human): S301‑p, ArgBP2 iso2 (human): S394‑p, ArgBP2 iso3 (human): S373‑p, ArgBP2 iso4 (human): S419‑p, ArgBP2 iso5 (human): S419‑p, ArgBP2 iso6 (human): S552‑p, ArgBP2 iso7 (human): S459‑p, ArgBP2 iso8 (human): S389‑p, ArgBP2 iso9 (human): S372‑p, ArgBP2 iso11 (human): S401‑p, ArgBP2 (mouse): S381‑p, ArgBP2 iso2 (mouse): S496‑p, ArgBP2 iso5 (mouse): S445‑p, ArgBP2 (rat): S396‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T1599-p - ARID1A (human)
Modsite: PRPMENRtsPsKsPF SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): T1599‑p, ARID1A iso2 (human): T1382‑p, ARID1A (mouse): T1600‑p, ARID1A (rat): T1607‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1602-p - ARID1A (human)
Modsite: MENRtsPsKsPFLHs SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): S1602‑p, ARID1A iso2 (human): S1385‑p, ARID1A (mouse): S1603‑p, ARID1A (rat): S1610‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1609-p - ARID1A (human)
Modsite: sKsPFLHsGMkMQKA SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): S1609‑p, ARID1A iso2 (human): S1392‑p, ARID1A (mouse): S1610‑p, ARID1A (rat): S1617‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S669-p - ataxin-2 (human)
Modsite: PVArtsPsGGtWsSV SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): S669‑p, ataxin‑2 iso2 (human): S669‑p, ataxin‑2 (mouse): A638‑p, ataxin‑2 iso2 (mouse): A568‑p, ataxin‑2 (rat): A201‑p, ataxin‑2 (cow): A651‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T672-p - ataxin-2 (human)
Modsite: rtsPsGGtWsSVVsG SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): T672‑p, ataxin‑2 iso2 (human): T672‑p, ataxin‑2 (mouse): T641‑p, ataxin‑2 iso2 (mouse): T571‑p, ataxin‑2 (rat): T204‑p, ataxin‑2 (cow): T654‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S255-p - ATG2B (human)
Modsite: VEtEPKLsPsWNPKI SwissProt Entrez-Gene
Orthologous residues
ATG2B (human): S255‑p, ATG2B iso100 (human): S255‑p, ATG2B (mouse): S255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S762-p - BCLAF1 (human)
Modsite: sAsPssPssREEKES SwissProt Entrez-Gene
Orthologous residues
BCLAF1 (human): S762‑p, BCLAF1 iso2 (human): S760‑p, BCLAF1 iso3 (human): S760‑p, BCLAF1 iso4 (human): S589‑p, BCLAF1 (mouse): S761‑p, BCLAF1 (rat): S763‑p, BCLAF1 iso3 (rat): S968‑p, BCLAF1 (cow): S763‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S299-p - BMI1 (human)
Modsite: TMNGTSNsPSGNHQS SwissProt Entrez-Gene
Orthologous residues
BMI1 (human): S299‑p, BMI1 (mouse): S297‑p, BMI1 (rat): S297‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S137-p - BMZF-2 (human)
Modsite: SRQPssPsHNTNLRA SwissProt Entrez-Gene
Orthologous residues
BMZF‑2 (human): S137‑p, BMZF‑2 iso2 (human): S140‑p, BMZF‑2 (mouse): S137‑p, BMZF‑2 (rat): S135‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S467-p - BRSK2 (human)
Modsite: PNPtPPssPSVGGVP SwissProt Entrez-Gene
Orthologous residues
BRSK2 (human): S467‑p, BRSK2 iso2 (human): S467‑p, BRSK2 iso3 (human): S467‑p, BRSK2 iso4 (human): S489‑p, BRSK2 iso5 (human): S513‑p, BRSK2 iso6 (human): S407‑p, BRSK2 (mouse): S468‑p, BRSK2 (rat): S468‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T314-p - CAF-1A (human)
Modsite: SstsPFPtstPLRRI SwissProt Entrez-Gene
Orthologous residues
CAF‑1A (human): T314‑p, CAF‑1A iso2 (human): T314‑p, CAF‑1A iso100 (human): T314‑p, CAF‑1A (mouse): P295‑p, CAF‑1A (rat): P295‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T848-p - CASKIN2 (human)
Modsite: tsPSVtPtPArGtPR SwissProt Entrez-Gene
Orthologous residues
CASKIN2 (human): T848‑p, CASKIN2 iso2 (human): T766‑p, CASKIN2 (mouse): T847‑p, CASKIN2 (rat): T847‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2356-p - CBP (human)
Modsite: VQsPrPQsQPPHssP SwissProt Entrez-Gene
Orthologous residues
CBP (human): S2356‑p, CBP iso2 (human): S2318‑p, CBP (mouse): S2355‑p, CBP (rat): S2356‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2361-p - CBP (human)
Modsite: PQsQPPHssPsPRIQ SwissProt Entrez-Gene
Orthologous residues
CBP (human): S2361‑p, CBP iso2 (human): S2323‑p, CBP (mouse): S2360‑p, CBP (rat): S2361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S494-p - CCDC132 (human)
Modsite: KFMEQsRsPsVsPsk SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S494‑p, CCDC132 iso3 (human): S464‑p, CCDC132 (mouse): S494‑p, CCDC132 (rat): S54‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2046-p - CHD-8 (human)
Modsite: QDyEMrVsPsDttPL SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): S2046‑p, CHD‑8 iso2 (human): S1767‑p, CHD‑8 (mouse): G2048‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): A2046‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T2050-p - CHD-8 (human)
Modsite: MrVsPsDttPLVsRS SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): T2050‑p, CHD‑8 iso2 (human): T1771‑p, CHD‑8 (mouse): T2052‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): T2050‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2055-p - CHD-8 (human)
Modsite: sDttPLVsRSVPPVK SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): S2055‑p, CHD‑8 iso2 (human): S1776‑p, CHD‑8 (mouse): S2056‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): S2054‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S805-p - DATF1 (human)
Modsite: AIPDLEDsPPVsDsE SwissProt Entrez-Gene
Orthologous residues
DATF1 (human): S805‑p, DATF1 iso1 (human): S805‑p, DATF1 iso3 (human): , DATF1 (mouse): S802‑p, DATF1 (rat): S645‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S121-p - EHMT2 (human)
Modsite: ksFPssPskGGSCPS SwissProt Entrez-Gene
Orthologous residues
EHMT2 (human): S121‑p, EHMT2 iso2 (human): S121‑p, EHMT2 iso4 (human): S178‑p, EHMT2 (mouse): S174‑p, EHMT2 iso4 (mouse): , EHMT2 (rat): S174‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1900-p - ELYS (human)
Modsite: VSTVTsPsRMIRKLR SwissProt Entrez-Gene
Orthologous residues
ELYS (human): S1900‑p, ELYS iso2 (human): S1935‑p, ELYS (mouse): D1886‑p, ELYS (rat): G1884‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S243-p - GTSE1 (human)
Modsite: PKKEIPAsPsRTKIP SwissProt Entrez-Gene
Orthologous residues
GTSE1 (human): S243‑p, GTSE1 (mouse): S245‑p, GTSE1 (rat): S254‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S245-p - GTSE1 (human)
Modsite: KEIPAsPsRTKIPAE SwissProt Entrez-Gene
Orthologous residues
GTSE1 (human): S245‑p, GTSE1 (mouse): Q247‑p, GTSE1 (rat): Q256‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S424-p - HDAC3 (human)
Modsite: DHDNDKEsDVEI___ SwissProt Entrez-Gene
Orthologous residues
HDAC3 (human): S424‑p, HDAC3 iso2 (human): S425‑p, HDAC3 (mouse): S424‑p, HDAC3 (rat): S424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S246-p - HDAC4 (human)
Modsite: FPLRkTAsEPNLKLR SwissProt Entrez-Gene
Orthologous residues
HDAC4 (human): S246‑p, HDAC4 (mouse): S245‑p, HDAC4 (rat): S245‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S467-p - HDAC4 (human)
Modsite: RPLGRtQsAPLPQNA SwissProt Entrez-Gene
Orthologous residues
HDAC4 (human): S467‑p, HDAC4 (mouse): S465‑p, HDAC4 (rat): S466‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S259-p - HDAC5 (human)
Modsite: FPLRkTAsEPNLKVR SwissProt Entrez-Gene
Orthologous residues
HDAC5 (human): S259‑p, HDAC5 iso2 (human): S259‑p, HDAC5 iso3 (human): S260‑p, HDAC5 (mouse): S250‑p, HDAC5 (rat): S83‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1108-p - HDAC5 (human)
Modsite: AAAAREHsPRPAEEP SwissProt Entrez-Gene
Orthologous residues
HDAC5 (human): S1108‑p, HDAC5 iso2 (human): S1023‑p, HDAC5 iso3 (human): S1109‑p, HDAC5 (mouse): S1099‑p, HDAC5 (rat): S932‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T678-p - HDAC6 (human)
Modsite: LHRYDHGtFFPMGDE SwissProt Entrez-Gene
Orthologous residues
HDAC6 (human): T678‑p, HDAC6 iso2 (human): T526‑p, HDAC6 (mouse): T677‑p, HDAC6 (rat): T677‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S155-p - HDAC7 (human)
Modsite: FPLRKtVsEPNLkLR SwissProt Entrez-Gene
Orthologous residues
HDAC7 (human): S155‑p, HDAC7 iso3 (human): S155‑p, HDAC7 iso5 (human): S194‑p, HDAC7 iso7 (human): S194‑p, HDAC7 iso8 (human): S211‑p, HDAC7 (mouse): S178‑p, HDAC7 (rat): S156‑p, HDAC7 (cow): S196‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S220-p - HDAC9 (human)
Modsite: FPLRkTAsEPNLKVR SwissProt Entrez-Gene
Orthologous residues
HDAC9 (human): S220‑p, HDAC9 iso3 (human): S220‑p, HDAC9 iso5 (human): S220‑p, HDAC9 iso6 (human): , HDAC9 (mouse): S220‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T2701-p - HERC1 (human)
Modsite: LPTRRAQtPPIssLP SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): T2701‑p, HERC1 (mouse): T2699‑p, HERC1 (rat): T2699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2705-p - HERC1 (human)
Modsite: RAQtPPIssLPtsPS SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2705‑p, HERC1 (mouse): S2703‑p, HERC1 (rat): S2703‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2706-p - HERC1 (human)
Modsite: AQtPPIssLPtsPSD SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2706‑p, HERC1 (mouse): S2704‑p, HERC1 (rat): S2704‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S412-p - HIVEP2 (human)
Modsite: EsAEQQIsPPNTNAK SwissProt Entrez-Gene
Orthologous residues
HIVEP2 (human): S412‑p, HIVEP2 (mouse): S412‑p, HIVEP2 (rat): S412‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T188-p - HP1 alpha (human)
Modsite: AENkEKEtAKs____ SwissProt Entrez-Gene
Orthologous residues
HP1 alpha (human): T188‑p, HP1 alpha (mouse): S188‑p, HP1 alpha (rat): S188‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1047-p - IARS (human)
Modsite: PLkPyPVsPsDkVLI SwissProt Entrez-Gene
Orthologous residues
IARS (human): S1047‑p, IARS (mouse): P1047‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1162-p - IRS2 (human)
Modsite: TttVtPVsPsFAHNP SwissProt Entrez-Gene
Orthologous residues
IRS2 (human): S1162‑p, IRS2 (mouse): S1151‑p, IRS2 (rat): S1154‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S971-p - KIAA1522 (human)
Modsite: PPVARKPsVGVPPPA SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S971‑p, KIAA1522 iso2 (human): S1030‑p, KIAA1522 (mouse): S952‑p, KIAA1522 iso2 (mouse): S1009‑p, KIAA1522 (rat): S956‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S979-p - KIAA1522 (human)
Modsite: VGVPPPAsPsyPRAE SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S979‑p, KIAA1522 iso2 (human): S1038‑p, KIAA1522 (mouse): S959‑p, KIAA1522 iso2 (mouse): S1016‑p, KIAA1522 (rat): S962‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S933-p - KIF5B (human)
Modsite: PGQHPAAsPtHPsAI SwissProt Entrez-Gene
Orthologous residues
KIF5B (human): S933‑p, KIF5B (mouse): S933‑p, KIF5B (rat): S933‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S48-p - KNOP1 (human)
Modsite: VsPLRAtsPsKsVAH SwissProt Entrez-Gene
Orthologous residues
KNOP1 (human): S48‑p, KNOP1 (mouse): S57‑p, TSG118 iso2 (mouse): S57‑p, KNOP1 (rat): S108‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S608-p - L3MBTL3 (human)
Modsite: sGEMPPAsPsFPRNK SwissProt Entrez-Gene
Orthologous residues
L3MBTL3 (human): S608‑p, L3MBTL3 iso2 (human): S583‑p, L3MBTL3 (mouse): T609‑p, L3MBTL3 (rat): S607‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S610-p - L3MBTL3 (human)
Modsite: EMPPAsPsFPRNKRT SwissProt Entrez-Gene
Orthologous residues
L3MBTL3 (human): S610‑p, L3MBTL3 iso2 (human): S585‑p, L3MBTL3 (mouse): S611‑p, L3MBTL3 (rat): S609‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S69-p - LSD1 (human)
Modsite: KKEPPRAsPPGGLAE SwissProt Entrez-Gene
Orthologous residues
LSD1 (human): S69‑p, LSD1 iso2 (human): S69‑p, LSD1 (mouse): S70‑p, LSD1 iso2 (mouse): S70‑p, LSD1 (rat): S69‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T280-p - MANSC1 (human)
Modsite: TVTSQPPtTLISTVF SwissProt Entrez-Gene
Orthologous residues
MANSC1 (human): T280‑p, MANSC1 (mouse): G275‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S633-p - MARK1 (human)
Modsite: AYNGPPAsPSHETGA SwissProt Entrez-Gene
Orthologous residues
MARK1 (human): S633‑p, MARK1 iso3 (human): S611‑p, MARK1 (mouse): S633‑p, MARK1 (rat): S633‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S222-p - MAVS (human)
Modsite: tPSRGPVsPsVSFQP SwissProt Entrez-Gene
Orthologous residues
MAVS (human): S222‑p, MAVS iso4 (human): S81‑p, MAVS (mouse): S220‑p, MAVS (rat): S220‑p, MAVS (cow): S221‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S154-p - MCMBP (human)
Modsite: NANQARVsPStsytP SwissProt Entrez-Gene
Orthologous residues
MCMBP (human): S154‑p, MCMBP iso2 (human): S154‑p, MCMBP (mouse): S154‑p, MCMBP (rat): S154‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S444-p - MEF2D (human)
Modsite: SIkSEPVsPsRERsP SwissProt Entrez-Gene
Orthologous residues
MEF2D (human): S444‑p, MEF2D iso2 (human): S443‑p, MEF2D iso4 (human): S437‑p, MEF2D (mouse): S437‑p, MEF2D iso2 (mouse): S437‑p, MEF2D (rat): S430‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S446-p - MEF2D (human)
Modsite: kSEPVsPsRERsPAP SwissProt Entrez-Gene
Orthologous residues
MEF2D (human): S446‑p, MEF2D iso2 (human): S445‑p, MEF2D iso4 (human): S439‑p, MEF2D (mouse): S439‑p, MEF2D iso2 (mouse): S439‑p, MEF2D (rat): S432‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S326-p - MIG-6 (human)
Modsite: VPPREPLsPSNsRTP SwissProt Entrez-Gene
Orthologous residues
MIG‑6 (human): S326‑p, MIG‑6 (mouse): S325‑p, MIG‑6 (rat): S324‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S330-p - MIG-6 (human)
Modsite: EPLsPSNsRTPsPKS SwissProt Entrez-Gene
Orthologous residues
MIG‑6 (human): S330‑p, MIG‑6 (mouse): S329‑p, MIG‑6 (rat): S328‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S2296-p - MLL4 (human)
Modsite: KEELGAssPsyGPPN SwissProt Entrez-Gene
Orthologous residues
MLL4 (human): S2296‑p, MLL4 iso3 (human): S2299‑p, MLL4 (mouse): S2253‑p, MLL4 (rat): S2245‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S593-p - MTM1 (human)
Modsite: PtsPssPsQMMPHVQ SwissProt Entrez-Gene
Orthologous residues
MTM1 (human): S593‑p, MTM1 (mouse): S593‑p, MTM1 (rat): A592‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S525-p - MYPT1 (human)
Modsite: DSsSLRTsSSytRRK SwissProt Entrez-Gene
Orthologous residues
MYPT1 (human): S525‑p, MYPT1 iso2 (human): S525‑p, MYPT1 iso3 (human): S525‑p, MYPT1 iso4 (human): S525‑p, MYPT1 (mouse): S525‑p, MYPT1 (rat): S525‑p, MYPT1 (pig): S525‑p, MYPT1 (chicken): G522‑p, MYPT1 (cow): S525‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S473-p - NFI-C (human)
Modsite: GGATSPtsPsysPPD SwissProt Entrez-Gene
Orthologous residues
NFI‑C (human): S473‑p, NFI‑C iso2 (human): S464‑p, NFI‑C (mouse): , NFI‑C (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T903-p - NUP188 (human)
Modsite: AIRDAFLtRLQskIE SwissProt Entrez-Gene
Orthologous residues
NUP188 (human): T903‑p, NUP188 iso2 (human): T792‑p, NUP188 (mouse): T903‑p, NUP188 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S907-p - NUP188 (human)
Modsite: AFLtRLQskIEDMRI SwissProt Entrez-Gene
Orthologous residues
NUP188 (human): S907‑p, NUP188 iso2 (human): S796‑p, NUP188 (mouse): S907‑p, NUP188 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S315-p - PHC3 (human)
Modsite: HQQIPLHsPPsKVSH SwissProt Entrez-Gene
Orthologous residues
PHC3 (human): S315‑p, PHC3 iso2 (human): S296‑p, PHC3 iso4 (human): , PHC3 iso7 (human): S327‑p, PHC3 (mouse): S312‑p, PHC3 (rat): S313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1796-p - PHF3 (human)
Modsite: PrTSTNFsPMrPQQP SwissProt Entrez-Gene
Orthologous residues
PHF3 (human): S1796‑p, PHF3 iso2 (human): S1708‑p, PHF3 (mouse): S1780‑p, PHF3 (rat): S1777‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S461-p - PHLDB1 (human)
Modsite: MRELPPLsPsLsRRA SwissProt Entrez-Gene
Orthologous residues
PHLDB1 (human): S461‑p, PHLDB1 iso2 (human): S461‑p, PHLDB1 (mouse): S463‑p, PHLDB1 (rat): S462‑p, PHLDB1 (cow): S463‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1847-p - POLR2A (human)
Modsite: tPtsPsysPssPEyt SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): S1847‑p, POLR2A iso100 (human): S1847‑p, POLR2A (mouse): S1847‑p, POLR2A (rat): S1847‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T714-p - PPFIA3 (human)
Modsite: GPAIPGDtPPPtPRs SwissProt Entrez-Gene
Orthologous residues
PPFIA3 (human): T714‑p, PPFIA3 iso2 (human): T714‑p, PPFIA3 (mouse): T714‑p, PPFIA3 (rat): T712‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S334-p - PRIC285 (human)
Modsite: FNRSSVAsGPIsPtN SwissProt Entrez-Gene
Orthologous residues
PRIC285 (human): S334‑p, PRIC285 iso2 (human): , PRIC285 (mouse): W580‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T340-p - PRIC285 (human)
Modsite: AsGPIsPtNYRQRMH SwissProt Entrez-Gene
Orthologous residues
PRIC285 (human): T340‑p, PRIC285 iso2 (human): , PRIC285 (mouse): S586‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T210-p - PYGB (human)
Modsite: FyGRVEHtPDGVKWL SwissProt Entrez-Gene
Orthologous residues
PYGB (human): T210‑p, PYGB (mouse): T210‑p, PYGB (rat): T210‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1103-p - RAP140 (human)
Modsite: GGNLPPVsPNDsGAK SwissProt Entrez-Gene
Orthologous residues
RAP140 (human): S1103‑p, RAP140 iso2 (human): S666‑p, RAP140 iso3 (human): S1103‑p, RAP140 (mouse): S1059‑p, RAP140 iso2 (mouse): S1089‑p, RAP140 (rat): S1097‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S841-p - RASAL2 (human)
Modsite: FTKRsTQsEDFSRRH SwissProt Entrez-Gene
Orthologous residues
RASAL2 (human): S841‑p, RASAL2 iso2 (human): S982‑p, RASAL2 (mouse): S988‑p, RASAL2 (rat): S639‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1695-p - RBBP6 (human)
Modsite: SRNQsHssPsVsPsR SwissProt Entrez-Gene
Orthologous residues
RBBP6 (human): S1695‑p, RBBP6 iso2 (human): S1661‑p, RBBP6 (mouse): S1695‑p, RBBP6 iso2 (mouse): S1661‑p, RBBP6 (rat): S1694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S1066-p - SETDB1 (human)
Modsite: RNYGYNPsPVkPEGL SwissProt Entrez-Gene
Orthologous residues
SETDB1 (human): S1066‑p, SETDB1 iso3 (human): S1066‑p, SETDB1 (mouse): , SETDB1 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S338-p - SIRT6 (human)
Modsite: PKRERPtsPAPHRPP SwissProt Entrez-Gene
Orthologous residues
SIRT6 (human): S338‑p, SIRT6 iso2 (human): S311‑p, SIRT6 (mouse): S317‑p, SIRT6 (rat): S313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T78-p - STX7 (human)
Modsite: kEFGsLPttPsEQRQ SwissProt Entrez-Gene
Orthologous residues
STX7 (human): T78‑p, STX7 iso2 (human): T78‑p, STX7 (mouse): T78‑p, STX7 (rat): T78‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S391-p - SUV39H1 (human)
Modsite: GLAGLPGsPKKRVRI SwissProt Entrez-Gene
Orthologous residues
SUV39H1 (human): S391‑p, SUV39H1 (mouse): S391‑p, SUV39H1 (rat): S392‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T86-p - TAX1BP3 (human)
Modsite: QVNGWDMtMVTHDQA SwissProt Entrez-Gene
Orthologous residues
TAX1BP3 (human): T86‑p, TAX1BP3 (mouse): T86‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S386-p - TCF12 (human)
Modsite: PGGQAPssPsYENsL SwissProt Entrez-Gene
Orthologous residues
TCF12 (human): S386‑p, TCF12 iso2 (human): S216‑p, TCF12 iso3 (human): S386‑p, TCF12 iso4 (human): S150‑p, TCF12 (mouse): S386‑p, TCF12 iso2 (mouse): S386‑p, TCF12 (rat): S387‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

Y389-p - TCF12 iso3 (human)
Modsite: QAPssPsyENsLHSL SwissProt Entrez-Gene
Orthologous residues
TCF12 (human): Y389‑p, TCF12 iso2 (human): Y219‑p, TCF12 iso3 (human): Y389‑p, TCF12 iso4 (human): Y153‑p, TCF12 (mouse): Y389‑p, TCF12 iso2 (mouse): Y389‑p, TCF12 (rat): Y390‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S203-p - TERF2IP (human)
Modsite: LLGDAPVsPssQkLK SwissProt Entrez-Gene
Orthologous residues
TERF2IP (human): S203‑p, TERF2IP (mouse): S200‑p, TERF2IP (rat): S200‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S205-p - TERF2IP (human)
Modsite: GDAPVsPssQkLKRK SwissProt Entrez-Gene
Orthologous residues
TERF2IP (human): S205‑p, TERF2IP (mouse): S202‑p, TERF2IP (rat): S202‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T440-p - TMEM201 (human)
Modsite: LFRSPRRtsPssLPG SwissProt Entrez-Gene
Orthologous residues
TMEM201 (human): T440‑p, TMEM201 (mouse): V440‑p, TMEM201 (rat): V440‑p, TMEM201 (cow): A443‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T553-p - TMEM201 (human)
Modsite: PPGEAPTtPSSSDEH SwissProt Entrez-Gene
Orthologous residues
TMEM201 (human): T553‑p, TMEM201 (mouse): T552‑p, TMEM201 (rat): T552‑p, TMEM201 (cow): T556‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S952-p - USP36 (human)
Modsite: DPEAMEEsPRKKKKR SwissProt Entrez-Gene
Orthologous residues
USP36 (human): S952‑p, USP36 iso2 (human): S952‑p, USP36 (mouse): L931‑p, USP36 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S52-p - VGLL4 (human)
Modsite: RtGPPPIsPsKRKFs SwissProt Entrez-Gene
Orthologous residues
VGLL4 (human): S52‑p, VGLL4 iso2 (human): S21‑p, VGLL4 iso4 (human): S58‑p, VGLL4 (mouse): S58‑p, VGLL4 (rat): S58‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

T212-p - WIRE (human)
Modsite: REKPLPPtPGQRLHP SwissProt Entrez-Gene
Orthologous residues
WIRE (human): T212‑p, WIRE iso2 (human): T62‑p, WIRE (mouse): T212‑p, WIRE (rat): T212‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S620-p - ZC3H14 (human)
Modsite: CAYHHPIsPCkAFPN SwissProt Entrez-Gene
Orthologous residues
ZC3H14 (human): S620‑p, ZC3H14 iso2 (human): S620‑p, ZC3H14 iso3 (human): S464‑p, ZC3H14 iso4 (human): S455‑p, ZC3H14 iso5 (human): S595‑p, ZC3H14 iso6 (human): S191‑p, ZC3H14 iso9 (human): S615‑p, ZC3H14 (mouse): S620‑p, ZC3H14 (rat): S620‑p, ZC3H14 (cow): S620‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S125-p - ZO1 (human)
Modsite: RPDPEPVsDNEEDsy SwissProt Entrez-Gene
Orthologous residues
ZO1 (human): S125‑p, ZO1 iso2 (human): S125‑p, ZO1 (mouse): S125‑p, ZO1 iso2 (mouse): S125‑p, ZO1 (rat): S113‑p, ZO1 (cow): S100‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved

S404-p - ZO1 (human)
Modsite: VDLPVsPsDGVLPNS SwissProt Entrez-Gene
Orthologous residues
ZO1 (human): S404‑p, ZO1 iso2 (human): S404‑p, ZO1 (mouse): S404‑p, ZO1 iso2 (mouse): S404‑p, ZO1 (rat): S392‑p, ZO1 (cow): S373‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3122 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  15hr 100nM geldanamycin, 1hr 1uM crizotinib, 24hr 100nM geldanamycin, 3hr 1uM crizotinib, Control Starved, Control Unstarved