Curated Information
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Home > Curated Information Page > Cst Curation Set #5202
Guo A (2008) CST Curation Set: 5202; Year: 2008; Biosample/Treatment: cell line, PC-12/NGF; Disease: pheochromocytoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T14-p - CDK1 (rat)
Modsite: IEKIGEGtyGVVyKG SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): T14‑p, CDK1 iso2 (human): T14‑p, CDK1 (mouse): T14‑p, CDK1 (rat): T14‑p, CDK1 (chicken): T14‑p, CDK1 (fruit fly): T14‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y15-p - CDK1 (rat)
Modsite: EKIGEGtyGVVyKGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

T14-p - CDK2 (rat)
Modsite: VEKIGEGtyGVVyKA SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): T14‑p, CDK2 iso2 (human): T14‑p, CDK2 (mouse): T14‑p, CDK2 (rat): T14‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y15-p - CDK2 (rat)
Modsite: EKIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y171-p - CHGB (rat)
Modsite: EEEEGKIyPKGEHRG SwissProt Entrez-Gene
Orthologous residues
CHGB (human): Y173‑p, CHGB (mouse): Y171‑p, CHGB (rat): Y171‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y424-p - CHGB (rat)
Modsite: RGREPGAyPALDsRQ SwissProt Entrez-Gene
Orthologous residues
CHGB (human): Y429‑p, CHGB (mouse): H427‑p, CHGB (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y321-p - DYRK1A (rat)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y273-p - DYRK1B (rat)
Modsite: LGQRIYQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y1109-p - EGFR (rat)
Modsite: GsVQNPVyHNQPLHP SwissProt Entrez-Gene
Orthologous residues
EGFR (human): Y1110‑p, EGFR iso2 (human): , EGFR iso5 (human): , EGFR (mouse): Y1110‑p, EGFR (rat): Y1109‑p, EGFR (pig): Y1109‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y1171-p - EGFR (rat)
Modsite: MSLDNPDyQQDFFPK SwissProt Entrez-Gene
Orthologous residues
EGFR (human): Y1172‑p, EGFR iso2 (human): , EGFR iso5 (human): , EGFR (mouse): Y1172‑p, EGFR (rat): Y1171‑p, EGFR (pig): Y1171‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y1196-p - EGFR (rat)
Modsite: PTAENAEyLRVAPPS SwissProt Entrez-Gene
Orthologous residues
EGFR (human): Y1197‑p, EGFR iso2 (human): , EGFR iso5 (human): , EGFR (mouse): Y1197‑p, EGFR (rat): Y1196‑p, EGFR (pig): Y1196‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

T203-p - ERK1 (rat)
Modsite: HDHTGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): T202‑p, ERK1 iso2 (human): T202‑p, ERK1 iso3 (human): T202‑p, ERK1 (mouse): T203‑p, ERK1 (rat): T203‑p, ERK1 (hamster): T192‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y205-p - ERK1 (rat)
Modsite: HTGFLtEyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y279-p - GSK3A (rat)
Modsite: RGEPNVsyICsRyYR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y216-p - GSK3B (rat)
Modsite: RGEPNVsyICsRyYR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y409-p - Hck (rat)
Modsite: RIIEDNEytAREGAK SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y70-p - IRAP (rat)
Modsite: MDEDEEDyESSAKLL SwissProt Entrez-Gene
Orthologous residues
IRAP (human): Y70‑p, IRAP (mouse): Y70‑p, IRAP (rat): Y70‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y784-p - ITGB1 (rat)
Modsite: DTGENPIyKSAVTTV SwissProt Entrez-Gene
Orthologous residues
ITGB1 (human): Y783‑p, ITGB1 iso2 (human): , ITGB1 iso3 (human): , ITGB1 iso5 (human): , ITGB1 (mouse): Y783‑p, ITGB1 iso5 (mouse): , ITGB1 (rat): Y784‑p, ITGB1 (hamster): Y783‑p, ITGB1 (chicken): Y788‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

S385-p - PARP8 (rat)
Modsite: KLLSKSYsSAPKSSK SwissProt Entrez-Gene
Orthologous residues
PARP8 (human): S434‑p, PARP8 iso2 (human): S434‑p, PARP8 (mouse): S433‑p, PARP8 (rat): S385‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y171-p - PTTG1IP (rat)
Modsite: LFKEQNPyEKF____ SwissProt Entrez-Gene
Orthologous residues
PTTG1IP (human): Y174‑p, PTTG1IP (mouse): Y171‑p, PTTG1IP (rat): Y171‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y75-p - SYP (rat)
Modsite: PFRLHQVyFDAPSCV SwissProt Entrez-Gene
Orthologous residues
SYP (human): Y81‑p, SYP (mouse): Y81‑p, SYP (rat): Y75‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y774-p - TMEM63A (rat)
Modsite: SPQQQQTyGAIRNIS SwissProt Entrez-Gene
Orthologous residues
TMEM63A (human): Y777‑p, TMEM63A (mouse): Y774‑p, TMEM63A (rat): Y774‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

S82-p - TRA2A (rat)
Modsite: SHRRRsRsRsYtPEY GenPept Entrez-Gene
Orthologous residues
TRA2A (human): S84‑p, TRA2A (mouse): S82‑p, TRA2A (rat): S82‑p, TRA2A (cow): S84‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y679-p - TrkA (rat)
Modsite: FGMSRDIySTDyyRV SwissProt Entrez-Gene
Orthologous residues
TrkA (human): Y676‑p, TrkA iso2 (human): Y670‑p, TrkA (mouse): Y679‑p, TrkA (rat): Y679‑p, TrkA iso2 (rat): Y673‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat

Y683-p - TrkA (rat)
Modsite: RDIySTDyyRVGGRT SwissProt Entrez-Gene
Orthologous residues
TrkA (human): Y680‑p, TrkA iso2 (human): Y674‑p, TrkA (mouse): Y683‑p, TrkA (rat): Y683‑p, TrkA iso2 (rat): Y677‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  adrenal cancer, pheochromocytoma
Relevant cell lines - cell types - tissues:  PC-12 (chromaffin)
Cellular systems studied:  cell lines
Species studied:  rat