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Home > Curated Information Page > Cst Curation Set #15873
Rikova K (2012) CST Curation Set: 15873; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](PSD)
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
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S187-p - AKAP10 (human)
Modsite: SSLAEPVsPsKKHET SwissProt Entrez-Gene
Orthologous residues
AKAP10 (human): S187‑p, AKAP10 (mouse): S187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S496-p - AMPKA1 (human)
Modsite: AtPQRsGsVsNyRSC SwissProt Entrez-Gene
Orthologous residues
AMPKA1 (human): S496‑p, AMPKA1 iso2 (human): S511‑p, AMPKA1 (mouse): S496‑p, AMPKA1 (rat): S496‑p, AMPKA1 (fruit fly):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S304-p - ArgBP2 (human)
Modsite: sssPssPsRAKGGDD SwissProt Entrez-Gene
Orthologous residues
ArgBP2 (human): S304‑p, ArgBP2 iso2 (human): S397‑p, ArgBP2 iso3 (human): S376‑p, ArgBP2 iso4 (human): S422‑p, ArgBP2 iso5 (human): S422‑p, ArgBP2 iso6 (human): S555‑p, ArgBP2 iso7 (human): S462‑p, ArgBP2 iso8 (human): S392‑p, ArgBP2 iso9 (human): S375‑p, ArgBP2 iso11 (human): S404‑p, ArgBP2 (mouse): S384‑p, ArgBP2 iso2 (mouse): S499‑p, ArgBP2 iso5 (mouse): S448‑p, ArgBP2 (rat): S399‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1029-p - ARHGAP29 (human)
Modsite: VDRLLLAsPPNERNG SwissProt Entrez-Gene
Orthologous residues
ARHGAP29 (human): S1029‑p, ARHGAP29 (mouse): S1039‑p, ARHGAP29 (rat): G1034‑p, ARHGAP29 (cow): S1037‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1604-p - ARID1A (human)
Modsite: NRtsPsKsPFLHsGM SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): S1604‑p, ARID1A iso2 (human): S1387‑p, ARID1A (mouse): S1605‑p, ARID1A (rat): S1612‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1609-p - ARID1A (human)
Modsite: sKsPFLHsGMkMQKA SwissProt Entrez-Gene
Orthologous residues
ARID1A (human): S1609‑p, ARID1A iso2 (human): S1392‑p, ARID1A (mouse): S1610‑p, ARID1A (rat): S1617‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S667-p - ataxin-2 (human)
Modsite: tPPVArtsPsGGtWs SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): S667‑p, ataxin‑2 iso2 (human): S667‑p, ataxin‑2 (mouse): S636‑p, ataxin‑2 iso2 (mouse): S566‑p, ataxin‑2 (rat): S199‑p, ataxin‑2 (cow): S649‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S669-p - ataxin-2 (human)
Modsite: PVArtsPsGGtWsSV SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): S669‑p, ataxin‑2 iso2 (human): S669‑p, ataxin‑2 (mouse): A638‑p, ataxin‑2 iso2 (mouse): A568‑p, ataxin‑2 (rat): A201‑p, ataxin‑2 (cow): A651‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T672-p - ataxin-2 (human)
Modsite: rtsPsGGtWsSVVsG SwissProt Entrez-Gene
Orthologous residues
ataxin‑2 (human): T672‑p, ataxin‑2 iso2 (human): T672‑p, ataxin‑2 (mouse): T641‑p, ataxin‑2 iso2 (mouse): T571‑p, ataxin‑2 (rat): T204‑p, ataxin‑2 (cow): T654‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S255-p - ATG2B (human)
Modsite: VEtEPKLsPsWNPKI SwissProt Entrez-Gene
Orthologous residues
ATG2B (human): S255‑p, ATG2B iso100 (human): S255‑p, ATG2B (mouse): S255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T373-p - BRAF (human)
Modsite: APNVHINtIEPVNID SwissProt Entrez-Gene
Orthologous residues
BRAF (human): T373‑p, BRAF (mouse): T356‑p, BRAF iso1 (mouse): T356‑p, BRAF (rat): T355‑p, BRAF (chicken): T373‑p, BRAF (quail): T373‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T848-p - CASKIN2 (human)
Modsite: tsPSVtPtPArGtPR SwissProt Entrez-Gene
Orthologous residues
CASKIN2 (human): T848‑p, CASKIN2 iso2 (human): T766‑p, CASKIN2 (mouse): T847‑p, CASKIN2 (rat): T847‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S492-p - CCDC132 (human)
Modsite: EFKFMEQsRsPsVsP SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S492‑p, CCDC132 iso3 (human): S462‑p, CCDC132 (mouse): S492‑p, CCDC132 (rat): S52‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S494-p - CCDC132 (human)
Modsite: KFMEQsRsPsVsPsk SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S494‑p, CCDC132 iso3 (human): S464‑p, CCDC132 (mouse): S494‑p, CCDC132 (rat): S54‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S496-p - CCDC132 (human)
Modsite: MEQsRsPsVsPskQP SwissProt Entrez-Gene
Orthologous residues
CCDC132 (human): S496‑p, CCDC132 iso3 (human): S466‑p, CCDC132 (mouse): S496‑p, CCDC132 (rat): S56‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S202-p - CGNL1 (human)
Modsite: PSNsQPtsPsLEDPA SwissProt Entrez-Gene
Orthologous residues
CGNL1 (human): S202‑p, CGNL1 (mouse): S203‑p, CGNL1 (rat): S202‑p, CGNL1 (cow): S202‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S2046-p - CHD-8 (human)
Modsite: QDyEMrVsPsDttPL SwissProt Entrez-Gene
Orthologous residues
CHD‑8 (human): S2046‑p, CHD‑8 iso2 (human): S1767‑p, CHD‑8 (mouse): G2048‑p, CHD‑8 iso2 (mouse): , CHD‑8 (rat): A2046‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S85-p - CRK (human)
Modsite: PPPGVsPsRLRIGDQ SwissProt Entrez-Gene
Orthologous residues
CRK (human): S85‑p, CRK iso2 (human): S85‑p, CRK (mouse): S85‑p, CRK iso3 (mouse): S85‑p, CRK (rat): S85‑p, CRK (chicken): T86‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S121-p - EHMT2 (human)
Modsite: ksFPssPskGGSCPS SwissProt Entrez-Gene
Orthologous residues
EHMT2 (human): S121‑p, EHMT2 iso2 (human): S121‑p, EHMT2 iso4 (human): S178‑p, EHMT2 (mouse): S174‑p, EHMT2 iso4 (mouse): , EHMT2 (rat): S174‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S196-p - FAM114A1 (human)
Modsite: tDQGPAEsPPtsPsS SwissProt Entrez-Gene
Orthologous residues
FAM114A1 (human): S196‑p, FAM114A1 (mouse): G194‑p, FAM114A1 (rat): G192‑p, FAM114A1 (cow): S196‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S245-p - GTSE1 (human)
Modsite: KEIPAsPsRTKIPAE SwissProt Entrez-Gene
Orthologous residues
GTSE1 (human): S245‑p, GTSE1 (mouse): Q247‑p, GTSE1 (rat): Q256‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S424-p - HDAC3 (human)
Modsite: DHDNDKEsDVEI___ SwissProt Entrez-Gene
Orthologous residues
HDAC3 (human): S424‑p, HDAC3 iso2 (human): S425‑p, HDAC3 (mouse): S424‑p, HDAC3 (rat): S424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1108-p - HDAC5 (human)
Modsite: AAAAREHsPRPAEEP SwissProt Entrez-Gene
Orthologous residues
HDAC5 (human): S1108‑p, HDAC5 iso2 (human): S1023‑p, HDAC5 iso3 (human): S1109‑p, HDAC5 (mouse): S1099‑p, HDAC5 (rat): S932‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S155-p - HDAC7 (human)
Modsite: FPLRKtVsEPNLkLR SwissProt Entrez-Gene
Orthologous residues
HDAC7 (human): S155‑p, HDAC7 iso3 (human): S155‑p, HDAC7 iso5 (human): S194‑p, HDAC7 iso7 (human): S194‑p, HDAC7 iso8 (human): S211‑p, HDAC7 (mouse): S178‑p, HDAC7 (rat): S156‑p, HDAC7 (cow): S196‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T2701-p - HERC1 (human)
Modsite: LPTRRAQtPPIssLP SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): T2701‑p, HERC1 (mouse): T2699‑p, HERC1 (rat): T2699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S2705-p - HERC1 (human)
Modsite: RAQtPPIssLPtsPS SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2705‑p, HERC1 (mouse): S2703‑p, HERC1 (rat): S2703‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S2706-p - HERC1 (human)
Modsite: AQtPPIssLPtsPSD SwissProt Entrez-Gene
Orthologous residues
HERC1 (human): S2706‑p, HERC1 (mouse): S2704‑p, HERC1 (rat): S2704‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T188-p - HP1 alpha (human)
Modsite: AENkEKEtAKs____ SwissProt Entrez-Gene
Orthologous residues
HP1 alpha (human): T188‑p, HP1 alpha (mouse): S188‑p, HP1 alpha (rat): S188‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

Y1044-p - IARS (human)
Modsite: IKAPLkPyPVsPsDk SwissProt Entrez-Gene
Orthologous residues
IARS (human): Y1044‑p, IARS (mouse): Y1044‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S971-p - KIAA1522 (human)
Modsite: PPVARKPsVGVPPPA SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S971‑p, KIAA1522 iso2 (human): S1030‑p, KIAA1522 (mouse): S952‑p, KIAA1522 iso2 (mouse): S1009‑p, KIAA1522 (rat): S956‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S979-p - KIAA1522 (human)
Modsite: VGVPPPAsPsyPRAE SwissProt Entrez-Gene
Orthologous residues
KIAA1522 (human): S979‑p, KIAA1522 iso2 (human): S1038‑p, KIAA1522 (mouse): S959‑p, KIAA1522 iso2 (mouse): S1016‑p, KIAA1522 (rat): S962‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S608-p - L3MBTL3 (human)
Modsite: sGEMPPAsPsFPRNK SwissProt Entrez-Gene
Orthologous residues
L3MBTL3 (human): S608‑p, L3MBTL3 iso2 (human): S583‑p, L3MBTL3 (mouse): T609‑p, L3MBTL3 (rat): S607‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T551-p - liprin beta 1 (human)
Modsite: LAEtEkEtAEHLDLA SwissProt Entrez-Gene
Orthologous residues
liprin beta 1 (human): T551‑p, liprin beta 1 iso2 (human): T545‑p, liprin beta 1 iso3 (human): T398‑p, liprin beta 1 iso4 (human): T520‑p, liprin beta 1 (mouse): T511‑p, liprin beta 1 iso4 (mouse): T110‑p, liprin beta 1 (rat): T471‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S69-p - LSD1 (human)
Modsite: KKEPPRAsPPGGLAE SwissProt Entrez-Gene
Orthologous residues
LSD1 (human): S69‑p, LSD1 iso2 (human): S69‑p, LSD1 (mouse): S70‑p, LSD1 iso2 (mouse): S70‑p, LSD1 (rat): S69‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S446-p - MEF2D (human)
Modsite: kSEPVsPsRERsPAP SwissProt Entrez-Gene
Orthologous residues
MEF2D (human): S446‑p, MEF2D iso2 (human): S445‑p, MEF2D iso4 (human): S439‑p, MEF2D (mouse): S439‑p, MEF2D iso2 (mouse): S439‑p, MEF2D (rat): S432‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T260-p - MTSS1L (human)
Modsite: DYSWsyQtPPssPsS SwissProt Entrez-Gene
Orthologous residues
MTSS1L (human): T260‑p, MTSS1L (mouse): T257‑p, MTSS1L (rat): T260‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S264-p - MTSS1L (human)
Modsite: syQtPPssPsSSsSR SwissProt Entrez-Gene
Orthologous residues
MTSS1L (human): S264‑p, MTSS1L (mouse): S261‑p, MTSS1L (rat): S264‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S310-p - occludin (human)
Modsite: AGtQDVPsPPsDyVE SwissProt Entrez-Gene
Orthologous residues
occludin (human): S310‑p, occludin iso2 (human): S256‑p, occludin iso3 (human): S310‑p, occludin (mouse): P308‑p, occludin (rat): P310‑p, occludin (chicken): A295‑p, occludin (cow): P310‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1796-p - PHF3 (human)
Modsite: PrTSTNFsPMrPQQP SwissProt Entrez-Gene
Orthologous residues
PHF3 (human): S1796‑p, PHF3 iso2 (human): S1708‑p, PHF3 (mouse): S1780‑p, PHF3 (rat): S1777‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1845-p - POLR2A (human)
Modsite: KytPtsPsysPssPE SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): S1845‑p, POLR2A iso100 (human): S1845‑p, POLR2A (mouse): S1845‑p, POLR2A (rat): S1845‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

Y1846-p - POLR2A (human)
Modsite: ytPtsPsysPssPEy SwissProt Entrez-Gene
Orthologous residues
POLR2A (human): Y1846‑p, POLR2A iso100 (human): Y1846‑p, POLR2A (mouse): Y1846‑p, POLR2A (rat): Y1846‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T714-p - PPFIA3 (human)
Modsite: GPAIPGDtPPPtPRs SwissProt Entrez-Gene
Orthologous residues
PPFIA3 (human): T714‑p, PPFIA3 iso2 (human): T714‑p, PPFIA3 (mouse): T714‑p, PPFIA3 (rat): T712‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T340-p - PRIC285 (human)
Modsite: AsGPIsPtNYRQRMH SwissProt Entrez-Gene
Orthologous residues
PRIC285 (human): T340‑p, PRIC285 iso2 (human): , PRIC285 (mouse): S586‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1103-p - RAP140 (human)
Modsite: GGNLPPVsPNDsGAK SwissProt Entrez-Gene
Orthologous residues
RAP140 (human): S1103‑p, RAP140 iso2 (human): S666‑p, RAP140 iso3 (human): S1103‑p, RAP140 (mouse): S1059‑p, RAP140 iso2 (mouse): S1089‑p, RAP140 (rat): S1097‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S1066-p - SETDB1 (human)
Modsite: RNYGYNPsPVkPEGL SwissProt Entrez-Gene
Orthologous residues
SETDB1 (human): S1066‑p, SETDB1 iso3 (human): S1066‑p, SETDB1 (mouse): , SETDB1 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T303-p - SF3B1 (human)
Modsite: tPKtERDtPGHGsGW SwissProt Entrez-Gene
Orthologous residues
SF3B1 (human): T303‑p, SF3B1 (mouse): T303‑p, SF3B1 (rat): T303‑p, SF3B1 (cow): T303‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S338-p - SIRT6 (human)
Modsite: PKRERPtsPAPHRPP SwissProt Entrez-Gene
Orthologous residues
SIRT6 (human): S338‑p, SIRT6 iso2 (human): S311‑p, SIRT6 (mouse): S317‑p, SIRT6 (rat): S313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T61-p - SMCR7L (human)
Modsite: IsAPtsPtRLSHSGk SwissProt Entrez-Gene
Orthologous residues
SMCR7L (human): T61‑p, SMCR7L iso2 (human): T61‑p, SMCR7L (mouse): T61‑p, SMCR7L (rat): T61‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S391-p - SUV39H1 (human)
Modsite: GLAGLPGsPKKRVRI SwissProt Entrez-Gene
Orthologous residues
SUV39H1 (human): S391‑p, SUV39H1 (mouse): S391‑p, SUV39H1 (rat): S392‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S203-p - TERF2IP (human)
Modsite: LLGDAPVsPssQkLK SwissProt Entrez-Gene
Orthologous residues
TERF2IP (human): S203‑p, TERF2IP (mouse): S200‑p, TERF2IP (rat): S200‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S52-p - VGLL4 (human)
Modsite: RtGPPPIsPsKRKFs SwissProt Entrez-Gene
Orthologous residues
VGLL4 (human): S52‑p, VGLL4 iso2 (human): S21‑p, VGLL4 iso4 (human): S58‑p, VGLL4 (mouse): S58‑p, VGLL4 (rat): S58‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

T212-p - WIRE (human)
Modsite: REKPLPPtPGQRLHP SwissProt Entrez-Gene
Orthologous residues
WIRE (human): T212‑p, WIRE iso2 (human): T62‑p, WIRE (mouse): T212‑p, WIRE (rat): T212‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S235-p - WIRE (human)
Modsite: PPVKPPPsPVNIRTG SwissProt Entrez-Gene
Orthologous residues
WIRE (human): S235‑p, WIRE iso2 (human): S85‑p, WIRE (mouse): S235‑p, WIRE (rat): S235‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S620-p - ZC3H14 (human)
Modsite: CAYHHPIsPCkAFPN SwissProt Entrez-Gene
Orthologous residues
ZC3H14 (human): S620‑p, ZC3H14 iso2 (human): S620‑p, ZC3H14 iso3 (human): S464‑p, ZC3H14 iso4 (human): S455‑p, ZC3H14 iso5 (human): S595‑p, ZC3H14 iso6 (human): S191‑p, ZC3H14 iso9 (human): S615‑p, ZC3H14 (mouse): S620‑p, ZC3H14 (rat): S620‑p, ZC3H14 (cow): S620‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2

S125-p - ZO1 (human)
Modsite: RPDPEPVsDNEEDsy SwissProt Entrez-Gene
Orthologous residues
ZO1 (human): S125‑p, ZO1 iso2 (human): S125‑p, ZO1 (mouse): S125‑p, ZO1 iso2 (mouse): S125‑p, ZO1 (rat): S113‑p, ZO1 (cow): S100‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H3255 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Comments:  1hr 1uM iressa, 24hr 1uM iressa, 3hr 1uM iressa, 6hr 1uM iressa, control1, control2