Matthews LC, et al. (2015) Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy. Proc Natl Acad Sci U S A 112, 5479-84 25847991

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S203-p - GR (human) ▲

Modsite: DLEFSSGsPGkEtNE SwissProt Entrez-Gene Orthologous residues GR (human): S203‑p, GR iso2 (human): S203‑p, GR iso3 (human): S203‑p, GR iso10 (human): S203‑p, GR (mouse): S221‑p, GR (rat): S224‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  HeLa (cervical) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes VX-680 decrease Downstream Regulation Effect of modification (function):  intracellular localization Comments:  recruited to centrosomes and subsequently phosphorylated during mitosis

S211-p - GR (human) ▲

Modsite: PGkEtNEsPWRSDLL SwissProt Entrez-Gene Orthologous residues GR (human): S211‑p, GR iso2 (human): S211‑p, GR iso3 (human): S211‑p, GR iso10 (human): S211‑p, GR (mouse): S229‑p, GR (rat): S232‑p Characterization Methods used to characterize site in vivo:  phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  HeLa (cervical) Cellular systems studied:  cell lines Species studied:  human Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes VX-680 decrease Downstream Regulation Effect of modification (function):  intracellular localization Comments:  recruited to centrosomes and subsequently phosphorylated during mitosis