Gupta N, Madapura MP, Bhat UA, Rao MR (2015) Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2, and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2. J Biol Chem 290, 12101-22 25818198

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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R5-me - TP1 (rat) ▲
Modsite: ___MSTSrkLKTHGM SwissProt Entrez-Gene Orthologous residues TP1 (human): R5‑me, TP1 (mouse): R5‑me, TP1 (rat): R5‑me, TP1 (sheep): R4‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K6-ac - TP1 (rat) ▲
Modsite: __MSTSrkLKTHGMr SwissProt Entrez-Gene Orthologous residues TP1 (human): K6‑ac, TP1 (mouse): K6‑ac, TP1 (rat): K6‑ac, TP1 (sheep): K5‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

R13-m2 - TP1 (rat) ▲
Modsite: kLKTHGMrRGKNrAP SwissProt Entrez-Gene Orthologous residues TP1 (human): R13‑m2, TP1 (mouse): R13‑m2, TP1 (rat): R13‑m2, TP1 (sheep): R12‑m2 Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

R18-me - TP1 (rat) ▲
Modsite: GMrRGKNrAPHkGVk SwissProt Entrez-Gene Orthologous residues TP1 (human): R18‑me, TP1 (mouse): R18‑me, TP1 (rat): R18‑me, TP1 (sheep): R17‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K22-ac - TP1 (rat) ▲
Modsite: GKNrAPHkGVkRGGS SwissProt Entrez-Gene Orthologous residues TP1 (human): K22‑ac, TP1 (mouse): K22‑ac, TP1 (rat): K22‑ac, TP1 (sheep): K21‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K25-me - TP1 (rat) ▲
Modsite: rAPHkGVkRGGSKRk SwissProt Entrez-Gene Orthologous residues TP1 (human): K25‑me, TP1 (mouse): K25‑me, TP1 (rat): K25‑me, TP1 (sheep): K24‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K32-ac - TP1 (rat) ▲
Modsite: kRGGSKRkYrkssLk SwissProt Entrez-Gene Orthologous residues TP1 (human): K32‑ac, TP1 (mouse): K32‑ac, TP1 (rat): K32‑ac, TP1 (sheep): K31‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

R34-me - TP1 (rat) ▲
Modsite: GGSKRkYrkssLkSr SwissProt Entrez-Gene Orthologous residues TP1 (human): R34‑me, TP1 (mouse): R34‑me, TP1 (rat): R34‑me, TP1 (sheep): R33‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K35-ac - TP1 (rat) ▲
Modsite: GSKRkYrkssLkSrk SwissProt Entrez-Gene Orthologous residues TP1 (human): K35‑ac, TP1 (mouse): K35‑ac, TP1 (rat): K35‑ac, TP1 (sheep): K34‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S36-p - TP1 (rat) ▲
Modsite: SKRkYrkssLkSrkR SwissProt Entrez-Gene Orthologous residues TP1 (human): G36‑p, TP1 (mouse): S36‑p, TP1 (rat): S36‑p, TP1 (sheep): S35‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S37-p - TP1 (rat) ▲
Modsite: KRkYrkssLkSrkRG SwissProt Entrez-Gene Orthologous residues TP1 (human): N37‑p, TP1 (mouse): V37‑p, TP1 (rat): S37‑p, TP1 (sheep): S36‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K39-ac - TP1 (rat) ▲
Modsite: kYrkssLkSrkRGDD SwissProt Entrez-Gene Orthologous residues TP1 (human): K39‑ac, TP1 (mouse): K39‑ac, TP1 (rat): K39‑ac, TP1 (sheep): K38‑ac

K39-me - TP1 (rat) ▲
Modsite: kYrkssLkSrkRGDD SwissProt Entrez-Gene Orthologous residues TP1 (human): K39‑me, TP1 (mouse): K39‑me, TP1 (rat): K39‑me, TP1 (sheep): K38‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

R41-me - TP1 (rat) ▲
Modsite: rkssLkSrkRGDDAs SwissProt Entrez-Gene Orthologous residues TP1 (human): R41‑me, TP1 (mouse): R41‑me, TP1 (rat): R41‑me, TP1 (sheep): R40‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K42-ac - TP1 (rat) ▲
Modsite: kssLkSrkRGDDAsR SwissProt Entrez-Gene Orthologous residues TP1 (human): K42‑ac, TP1 (mouse): K42‑ac, TP1 (rat): K42‑ac, TP1 (sheep): K41‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S48-p - TP1 (rat) ▲
Modsite: rkRGDDAsRNYRSHL SwissProt Entrez-Gene Orthologous residues TP1 (human): N48‑p, TP1 (mouse): S48‑p, TP1 (rat): S48‑p, TP1 (sheep): N47‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K4-ac - TP2 (rat) ▲
Modsite: ____MDTkMQsLPTT SwissProt Entrez-Gene Orthologous residues TP2 (human): Q4‑ac, TP2 (mouse): K4‑ac, TP2 (rat): K4‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S7-ac - TP2 (rat) ▲
Modsite: _MDTkMQsLPTTHPH SwissProt Entrez-Gene Orthologous residues TP2 (human): S7‑ac, TP2 (mouse): S7‑ac, TP2 (rat): S7‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S17-p - TP2 (rat) ▲
Modsite: TTHPHPHsSSRPQsH SwissProt Entrez-Gene Orthologous residues TP2 (human): S17‑p, TP2 (mouse): S17‑p, TP2 (rat): S17‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S23-p - TP2 (rat) ▲
Modsite: HsSSRPQsHTNNQCA SwissProt Entrez-Gene Orthologous residues TP2 (human): S23‑p, TP2 (mouse): S23‑p, TP2 (rat): S23‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S37-ac - TP2 (rat) ▲
Modsite: ACSHHCRsCsQAGHP SwissProt Entrez-Gene Orthologous residues TP2 (human): T32‑ac, TP2 (mouse): S40‑ac, TP2 (rat): S37‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S51-p - TP2 (rat) ▲
Modsite: PSSSSSPsPGPPTkH SwissProt Entrez-Gene Orthologous residues TP2 (human): N74‑p, TP2 (mouse): S54‑p, TP2 (rat): S51‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K57-ac - TP2 (rat) ▲
Modsite: PsPGPPTkHPKTPMH SwissProt Entrez-Gene Orthologous residues TP2 (human): K80‑ac, TP2 (mouse): K60‑ac, TP2 (rat): K57‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S68-p - TP2 (rat) ▲
Modsite: TPMHSRYsPsrPSHr SwissProt Entrez-Gene Orthologous residues TP2 (human): S91‑p, TP2 (mouse): S71‑p, TP2 (rat): S68‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

S70-p - TP2 (rat) ▲
Modsite: MHSRYsPsrPSHrGS SwissProt Entrez-Gene Orthologous residues TP2 (human): M93‑p, TP2 (mouse): A73‑p, TP2 (rat): S70‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

R71-me - TP2 (rat) ▲

Modsite: HSRYsPsrPSHrGSC SwissProt Entrez-Gene Orthologous residues TP2 (human): R94‑me, TP2 (mouse): R74‑me, TP2 (rat): R71‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme METHYLTRANSFERASE CARM1 (human)

R75-me - TP2 (rat) ▲

Modsite: sPsrPSHrGSCPKNR SwissProt Entrez-Gene Orthologous residues TP2 (human): H99‑me, TP2 (mouse): R78‑me, TP2 (rat): R75‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme METHYLTRANSFERASE CARM1 (human)

K83-ac - TP2 (rat) ▲
Modsite: GSCPKNRktLEGkVs SwissProt Entrez-Gene Orthologous residues TP2 (human): K107‑ac, TP2 (mouse): K86‑ac, TP2 (rat): K83‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K83-m2 - TP2 (rat) ▲
Modsite: GSCPKNRktLEGkVs SwissProt Entrez-Gene Orthologous residues TP2 (human): K107‑m2, TP2 (mouse): K86‑m2, TP2 (rat): K83‑m2 Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

T84-p - TP2 (rat) ▲
Modsite: SCPKNRktLEGkVsk SwissProt Entrez-Gene Orthologous residues TP2 (human): N108‑p, TP2 (mouse): T87‑p, TP2 (rat): T84‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K88-ac - TP2 (rat) ▲
Modsite: NRktLEGkVskrkAV SwissProt Entrez-Gene Orthologous residues TP2 (human): K112‑ac, TP2 (mouse): K91‑ac, TP2 (rat): K88‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K88-me - TP2 (rat) ▲

Modsite: NRktLEGkVskrkAV SwissProt Entrez-Gene Orthologous residues TP2 (human): K112‑me, TP2 (mouse): K91‑me, TP2 (rat): K88‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme METHYLTRANSFERASE SETD7 (human)

S90-p - TP2 (rat) ▲
Modsite: ktLEGkVskrkAVRR SwissProt Entrez-Gene Orthologous residues TP2 (human): K114‑p, TP2 (mouse): S93‑p, TP2 (rat): S90‑p Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K91-ac - TP2 (rat) ▲
Modsite: tLEGkVskrkAVRRR SwissProt Entrez-Gene Orthologous residues TP2 (human): K115‑ac, TP2 (mouse): K94‑ac, TP2 (rat): K91‑ac Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat

K91-me - TP2 (rat) ▲

Modsite: tLEGkVskrkAVRRR SwissProt Entrez-Gene Orthologous residues TP2 (human): K115‑me, TP2 (mouse): K94‑me, TP2 (rat): K91‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme METHYLTRANSFERASE SETD7 (human)

R92-me - TP2 (rat) ▲

Modsite: LEGkVskrkAVRRRK SwissProt Entrez-Gene Orthologous residues TP2 (human): K116‑me, TP2 (mouse): R95‑me, TP2 (rat): R92‑me Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat Enzymes shown to modify site in vitro:  Type Enzyme METHYLTRANSFERASE CARM1 (human)

R92-m2 - TP2 (rat) ▲
Modsite: LEGkVskrkAVRRRK SwissProt Entrez-Gene Orthologous residues TP2 (human): K116‑m2, TP2 (mouse): R95‑m2, TP2 (rat): R92‑m2 Characterization Methods used to characterize site in vivo:  flow cytometry, mass spectrometry Relevant cell lines - cell types - tissues:  testis Cellular systems studied:  tissue Species studied:  rat