Curated Information
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Home > Curated Information Page > PubMed Id: 10644707
Zhou TH, et al. (2000) Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. J Biol Chem 275, 2513-9 10644707
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T18-p - MST3 (human)
Modsite: ALNKRRAtLPHPGGS SwissProt Entrez-Gene
Orthologous residues
MST3 (human): T18‑p, MST3 iso2 (human): , MST3 (mouse): , MST3 (rat):
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mutation of modification site
Relevant cell lines - cell types - tissues:  293 (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE PKACA (human) pharmacological inhibitor of upstream enzyme, pharmacological activator of upstream enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
colforsin increase
H-89 colforsin inhibit treatment-induced increase
Downstream Regulation
Effect of modification (function):  activity, induced