Kobayashi T, et al. (1998) Isoform specific phosphorylation of protein phosphatase 2C expressed in COS7 cells. FEBS Lett 430, 222-6 9688543

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S375-p - PPPM1A (mouse) ▲

Modsite: YKNDDtDsAstDDMW SwissProt Entrez-Gene Orthologous residues PPPM1A (human): S375‑p, PPPM1A iso2 (human): ‑, PPPM1A iso3 (human): S448‑p, PPPM1A (mouse): S375‑p, PPPM1A (rat): S375‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (mouse) Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes okadaic_acid increase ciclosporin no change compared to control

S377-p - PPPM1A (mouse) ▲

Modsite: NDDtDsAstDDMW__ SwissProt Entrez-Gene Orthologous residues PPPM1A (human): S377‑p, PPPM1A iso2 (human): ‑, PPPM1A iso3 (human): S450‑p, PPPM1A (mouse): S377‑p, PPPM1A (rat): S377‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Species studied:  green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (mouse) Comments:  Minor phosphorylation site. Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes okadaic_acid increase ciclosporin no change compared to control